Patents by Inventor Sonu SHUKLA

Sonu SHUKLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of boronic acid esters
    Patent number: 11667654
    Abstract: The present invention relates to an improved process for the preparation of a compound of formula (I), wherein PG1 may be independently selected from tert-butyloxycarbonyl (Boc), phthaloyl, 9-fluorenylmethyloxycarbonyl (Fmoc), triphenylmethyl (Trityl), carboxybenzyl (Cbz), trifluoroacetyl, benzyl (Bn), benzylidene, methanesulfonyl (Mesyl), toluene sulfonyl (Tosyl) or acyl; its isolation as solid and use for the preparation of the compound of formula (IV), in particular the compound of formula (IV) i.e. [(1R)-3-methyl-1[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid with more than 99.95% chiral purity, as measured by HPLC.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: June 6, 2023
    Assignee: Fresenius Kabi Oncology Ltd.
    Inventors: Maneesh Kumar Pandey, Raj Narayan Tiwari, Sonu Shukla, Sarbjot Singh Sokhi, Govind Singh, Saswata Lahiri, Walter Cabri
  • Process for the preparation of ribociclib and its salts
    Patent number: 11440912
    Abstract: The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: September 13, 2022
    Assignee: FRESENIUS KABI ONCOLOGY LTD
    Inventors: Sarbjot Singh Sokhi, Govind Singh, Saswata Lahiri, Maneesh Kumar Pandey, Raj Narayan Tiwari, Sonu Shukla, Sachin Musmade, Heena Dua, Walter Cabri
  • AN IMPROVED PROCESS FOR THE PREPARATION OF RIBOCICLIB AND ITS SALTS
    Publication number: 20200277295
    Abstract: The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.
    Type: Application
    Filed: October 26, 2018
    Publication date: September 3, 2020
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Sarbjot Singh SOKHI, Govind SINGH, Saswata LAHIRI, Maneesh Kumar PANDEY, Raj Narayan TIWARI, Sonu SHUKLA, Sachin MUSMADE, Heena DUA, Walter CABRI
  • AN IMPROVED PROCESS FOR THE PREPARATION OF BORONIC ACID ESTERS
    Publication number: 20200031850
    Abstract: The present invention relates to an improved process for the preparation of a compound of formula (I), wherein PG1 may be independently selected from tert-butyloxycarbonyl (Boc), phthaloyl, 9-fluorenylmethyloxycarbonyl (Fmoc), triphenylmethyl (Trityl), carboxybenzyl (Cbz), trifluoroacetyl, benzyl (Bn), benzylidene, methanesulfonyl (Mesyl), toluene sulfonyl (Tosyl) or acyl; its isolation as solid and use for the preparation of the compound of formula (IV), in particular the compound of formula (IV) i.e. [(1R)-3-methyl-1[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid with more than 99.95% chiral purity, as measured by HPLC.
    Type: Application
    Filed: February 19, 2018
    Publication date: January 30, 2020
    Applicant: FRESENIUS KABI ONCOLOGY LIMITED
    Inventors: Maneesh Kumar PANDEY, Raj Narayan TIWARI, Sonu SHUKLA, Sarbjot Singh SOKHI, Govind SINGH, Saswata LAHIRI, Walter CABRI