Abstract: The present specification relates to a transgenic animal and a transgenic embryo producing components of an engineered nuclease. According to the disclosure of the present specification, the transgenic animal (or embryo) producing components of an engineered nuclease is a transgenic animal (or embryo) which includes a first cell having a genome including a first toolbox; and a second cell having a genome including a second toolbox, wherein the first toolbox and the second toolbox include at least one of a polynucleotide encoding an RNA-guided endonuclease and a polynucleotide encoding a guide nucleic acid that is able to specifically bind to a target site, respectively, wherein the first toolbox is present in a first locus of the genome of the first cell; the second toolbox is present in a second locus of the genome of the second cell; and the first locus is different from the second locus.

Abstract: A substrate transfer robot for transferring a substrate in a vacuum chamber, includes: a transfer arm platform having coupling holes, each compartmentalized into a lower and an upper space, wherein a link connecting member with blades is engaged at a front area of the transfer arm platform and a support shaft of a lower support is inserted into the lower space of one of the coupling holes; and a first and a second transfer arm part each including an end effector for supporting the substrate, multiple transfer link arms and subordinate link arms, and a common link arm that are connected to each other or to the transfer arm platform, wherein, for each transfer arm part, drive shafts, interlocked with transfer driving motors or speed reducers installed on one of the transfer link arms, and output shafts interlocked with the drive shafts are installed on the transfer link arms.

Abstract: A system for aligning items, which includes a packaging box transfer device to transfer a packaging box accommodating items therein, a fixing device to fix, at a withdrawal position where the items are taken out of the packaging box, the packaging box transferred by the packaging box transfer device with its top open, a withdrawal device to move to a space in which the items are accommodated in the packaging box so as to suck and take out the items, an item transfer device to transfer the items taken out by the withdrawal device with the items placed on the item transfer device, a sensor mounted on the withdrawal device to detect directions of the items taken out by the withdrawal device, and a rotating device to rotate the items taken out by the withdrawal device with the items placed on the rotating device.

Abstract: A packing box folding system, and the packing box folding system including a transfer conveyor on which transfers the packing box from a packing box introducing position to a folded packing box discharging position; a fixed guide panel which extends between the packing box introducing position and the packing box discharging position and is disposed on one side of the transfer conveyor in the width-direction; and a movable suction device which is disposed on the side opposite to the fixed guide panel in the width-direction of the transfer conveyor and is movable between the packing box introducing position and the packing box discharging position, wherein the movable suction device suctions the side surface of the packing box, which faces the side surface in contact with the fixed guide panel, and presses the suctioned side surface inward in the width-direction.

Abstract: The present application relates to a method of producing or purifying an FGF21 protein by using the heat-elasticity of FGF21. The method of producing or purifying the FGF21 protein according to an embodiment of the present application utilizes the heat stability and heat-elasticity of the FGF21 protein that is not denatured or precipitated even upon heat treatment and returns to the original structure when re-cooled after heat treatment, resulting in advantages of improving efficiency by simplifying a protein production process.

Abstract: A display apparatus and a method of manufacturing the same are discussed. In one example, the display apparatus includes a flexible display panel having a curved portion, a cover member attached to a display surface of the display panel, and a flexible plate adhered to a rear surface of the display panel. Further, the flexible plate includes a flexible thin sheet and at least one plate.

Abstract: An embodiment is a seat height gear system including a monopost apparatus configured to be mounted under a seat, the monopost apparatus comprising a lower post and an upper post, and a direct drive motor apparatus within the monopost apparatus, the direct drive motor apparatus including a motor and a gear unit, the gear unit including a pinion and a rack bar, the rack bar being configured to be engaged with the pinion, the motor being fixed to the lower post of the monopost apparatus, the pinion being coupled to the motor, the rack bar being fixed to an upper post of the monopost apparatus, the motor being configured to rotate the pinion, and the rack bar being configured to convert the rotation of the pinion into the linear motion.

Abstract: A medical instrument positioning tracking system includes: a bar-type medical instrument which has a bar shape front end part and an identification segment formed on the rear end part; a tracking multi-camera including a plurality of cameras provided at a plurality of locations so that the identification segment can be photographed in a plurality of time points; a display device for displaying an augmented reality image with the medical instrument as an augmented object and also displaying relevant information including location and angle of the medical instrument; and a control device for acquiring, in real time, a tracking image captured by the tracking multi-camera for every frame, estimating a three-dimensional segment by using the acquired image, estimating the actual three-dimensional positioning of the medical instrument by using the location relationship between a pre-measured location of the medical instrument and the three-dimensional segment, and displaying the estimated three-dimensional positioni

Abstract: The present disclosure provides a platform system for transmitting a video in real time with ultra-low latency, the platform system including: a caster unit (100) configured to encode and transmits a video signal provided from one or a plurality of video sources (110) through a network communication network; a platform server (200) configured to provide the video signal transmitted from the caster unit in a streaming manner; and a user terminal (300) configured to be provided with the video signal from the platform server in a streaming manner. The platform system and method for transmitting a video in real time with ultra-low latency according to the present disclosure has the advantage that it is possible to provide an ultra-low latency service anytime anywhere as long as the internet is connected by enabling real-time transmission of an end-to-end video signal.

Abstract: An apparatus for video representation learning according to an embodiment may extract video features from video data to generate a video embedding, extract image features from image data extracted from the video data to generate an image embedding, and extract audio features from audio data extracted from the video data to generate an audio embedding. Further, contrastive learning may be performed by generating a first compositional embedding based on the video embedding and the audio embedding, generating a second compositional embedding based on the video embedding and the audio embedding, generating a positive sample and a negative sample based on a correlation between the image embedding and the audio embedding, and then using the data.

Abstract: An apparatus for video representation learning according to an embodiment may extract video features from video data to generate a video embedding, extract image features from image data extracted from the video data to generate an image embedding, and extract audio features from audio data extracted from the video data to generate an audio embedding. Further, contrastive learning may be performed by generating a first compositional embedding based on the video embedding and the audio embedding, generating a second compositional embedding based on the video embedding and the audio embedding, generating a positive sample and a negative sample based on a correlation between the image embedding and the audio embedding, and then using the data.

Abstract: The present disclosure provides a platform system for transmitting a video in real time with ultra-low latency, the platform system including: a caster unit (100) configured to encode and transmits a video signal provided from one or a plurality of video sources (110) through a network communication network; a platform server (200) configured to provide the video signal transmitted from the caster unit in a streaming manner; and a user terminal (300) configured to be provided with the video signal from the platform server in a streaming manner. The platform system and method for transmitting a video in real time with ultra-low latency according to the present disclosure has the advantage that it is possible to provide an ultra-low latency service anytime anywhere as long as the internet is connected by enabling real-time transmission of an end-to-end video signal.

Abstract: The present disclosure provides an apparatus and method for encoding a video with ultra-low latency, the apparatus including: one or a plurality of video sources configured to provide a video signal; an encoder configured to encode the video signal provided through the video source and provided for each of the video sources; and a caster configured to transmit video data encoded by the encoder to the outside through a network communication network. Accordingly, the present disclosure can transmit a video with ultra-low latency, so a video service is possible in real time anytime anywhere as long as the internet is connected, whereby there is the advantage that the present disclosure can be applied to various fields of 4th industry such as autonomous driving, unmanned drone operation, driving of unmanned heavy equipment, robot control, a remote medical service, VR/AR, an intelligent CCTV, a smart city?factory, provision of traffic information, etc.

Abstract: A computer-implemented system and method of application topology visualization of a computing environment is disclosed. The application topology visualization obtains relationship data for a plurality of managed components, wherein the plurality of managed components have an application operating thereon. Event data for the plurality of managed components is also obtained. An application topology visualizer is used to generate the application topology visualization of the computing environment including the plurality of managed components, wherein the application topology visualization uses the relationship data and the event data for the plurality of managed components. A graphical user interface is used to display the application topology visualization of the computing environment as a single page.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer comprising an antiviral agent and an antidepressant as an active ingredient and to which a biguanide-based compound can be added, and more specifically, efavirenz, etravirine, rilpivirine, lopinavir, atazanavir, darunavir, and ritonavir as an antiviral agent, and fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, amitriptyline, clomipramine, nortriptyline, desipramine, amoxapine, maprotilline, trimipramine, protriptyline, and melithracene as an antidepressant, in complex, mixture, or combination administration, or efavirenz and fluoxetine with metformin, a biguanide compound, in complex, mixture, or combination administration, shows the significant synergistic anti-cancer activity than when each was administered alone, and so, finally the antiviral agent and antidepressant according to the present invention can be effectively used as an active ingredient in a composition for preventing or treating cancer.

Abstract: The present invention relates to a pharmaceutical composition comprising trimethobenzamide or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating neuropathy. Trimethobenzamide, when administered in combination with tramadol, exhibits the effect of significantly reducing pain in a neuropathy animal model and as such, can be advantageously used for treatment of neuropathy.

Abstract: A combined reflectance confocal and two-photon microscopy system for non-invasive high-speed/high-contrast examination of living tissue and a method for non-invasive high-speed/high-contrast examination of living tissue using the same, wherein the combined reflectance confocal and two-photon microscopy system enables high speed imaging while providing extracellular matrix/cell contrast together with information of existing reflectance confocal microscopy.

Abstract: A display device includes a substrate, a first pixel electrode disposed on the substrate, and including a first region and a second region electrically connected to each other without overlapping each other, a pixel defining layer disposed on the substrate on which the first pixel electrode is disposed, the pixel defining layer defining a first opening penetrating the pixel defining layer in a thickness direction and exposing the first region of the first pixel electrode, and a second opening penetrating the pixel defining layer in the thickness direction, exposing the second region of the first pixel electrode and separated from the first opening, and a light emitting layer disposed in the first opening exposing the first region of the first pixel electrode and the second opening exposing the second region of the first pixel electrode.

Abstract: Embodiments provide a process for purifying an alkylene oxide composition, which comprises (1) obtaining a crude alkylene oxide composition comprising an ionic component; (2) passing the crude alkylene oxide composition through a molecular sieve; and (3) obtaining a purified alkylene oxide composition. A purified alkylene oxide composition suitable for a subsequent process can be obtained.

Abstract: Disclosed are a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract, and more particularly, to a pharmaceutical composition for preventing or treating a skin disease containing a purple corn extract that has a potent effect of preventing or treating at least one skin disease selected from the group consisting of atopy, psoriasis, eczema, keratosis, prurigo and warts, using the purple corn extract.