Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: Disclosed are an ultra-high sensitivity target signal detection method based on analysis of a noise signal of a sensor using deep learning based anomaly detection and a system using the same. More particularly, disclosed are a method and apparatus for receiving a noise signal from a sensor and inputting data to an artificial neural network trained with a normal noise signal to determine whether or not a target signal is present. The target signal detection method is capable of detecting a target signal having a very low concentration that can be detected by a conventional sensor, whereby the target signal detection method is useful in developing an ultra-high sensitivity sensor.

Abstract: The present disclosure relates to a sensor including a nanostructure and a method for manufacturing the same.