Patents by Inventor Soo Yong LAU
Soo Yong LAU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11920191Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.Type: GrantFiled: January 18, 2021Date of Patent: March 5, 2024Assignee: Life Technologies CorporationInventors: Mingsong Chen, Kuan Moon Boo, Tiong Han Toh, Mauro Aguanno, Soo Yong Lau, Huei Yeo, Wei Fuh Teo
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Patent number: 11815460Abstract: A method of analyzing a plurality of biological sample volumes comprises emitting, along an excitation optical path toward a sample holder holding the plurality of biological sample volumes, electromagnetic radiation from a broadband LED, wherein the broadband LED emits the electromagnetic radiation across a range of wavelengths at a total output power of at least 5 watts and at a maximum intensity at a wavelength less than 600 nanometers and at an intensity less than 30 percent of the maximum intensity at a wavelength of 650 or 670 nanometers, and receiving, by a sensor, an electromagnetic emission transmitted from the sample holder along an emission optical path.Type: GrantFiled: May 26, 2022Date of Patent: November 14, 2023Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Kevin Maher, Mingsong Chen, Jacob K. Freudenthal, Kuan Moon Boo, Soo Yong Lau, David Fortescue, Ming Shen, Woon Liang Terence Soh
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Publication number: 20230221343Abstract: A biological analysis system for performing a performing an assay or experiment includes one or more of a carrier, base, or tray. The carrier, base, or tray is/are configured to interchangeably receive (1) a first block and a corresponding first cover placed over the first block or (2) a second block and a corresponding second cover placed over the second block; The system also includes a computer readable memory comprising instructions for detecting when the second cover is placed over the first block and/or for detecting when the first cover is placed over the second block based on lack of electrical continuity along an electrical path comprising one of the blocks and one of the covers.Type: ApplicationFiled: May 8, 2021Publication date: July 13, 2023Applicant: Life Technologies Holdings PTE LimitedInventors: Kuan Moon Boo, Wei Fuh Teo, Zeqi Tan, Ming Tiong Sia, Ching Yee Lam, Shan Hua Dong, Woon Liang Soh, Soo Yong Lau
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Publication number: 20230221280Abstract: A gel electrophoresis system includes a base module and a camera module. The base module includes a cassette slot for receiving a gel electrophoresis cassette, and a light element that functions to illuminate the gel electrophoresis cassette. The camera module is selectively attachable to and detachable from the base module. When attached to the base module, the camera module facilitates imaging of the gel electrophoresis cassette and provides additional imaging capabilities.Type: ApplicationFiled: December 20, 2022Publication date: July 13, 2023Inventors: Beng Heng LIM, Wuh Ken LOH, Hwee Siong KUAH, Jing Han WONG, Jefferson Cruz GANGCUANGCO, Jin Xin ONG, Soo Yong LAU, Yanping XU, Victor SHAPIRO, Zhi Da TEH, Chee Woei CHONG, Kuan Moon BOO
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Publication number: 20230031117Abstract: A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.Type: ApplicationFiled: October 14, 2022Publication date: February 2, 2023Applicants: Life Technologies Holdings PTE Limited, Life Technologies CorporationInventors: Kuan Moon Boo, Wei Fuh Teo, Zeqi Tan, Soo Yong Lau, Ming Tiong Sia, Woon Liang Soh, Ching Yee Lam, Shan Hua Dong, Marc Haberstroh, Michael C. Pallas, Hardeep Sangha
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Publication number: 20220412890Abstract: An instrument for processing and/or measuring a biological process comprises a plurality of filter assemblies configured to be interchangeably located along at least one of the optical paths. The plurality of filter components includes a first filter assembly characterized by a first optical power and a first filter having a first filter function, the first filter function characterized by at least one of a first low-pass wavelength or a first high-pass wavelength. The second filter assembly is characterized by a second optical power and a second filter having a second filter function, the second filter function comprising at least one of a second low-pass wavelength that is different than the first low-pass wavelength or a second high-pass wavelength that is different than the first high-pass wavelength.Type: ApplicationFiled: May 26, 2022Publication date: December 29, 2022Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Kevin MAHER, Mingsong CHEN, Jacob K. FREUDENTHAL, Kuan Moon BOO, Soo Yong LAU, David FORTESCUE, Ming SHEN, Woon Liang Terence SOH
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Patent number: 11480584Abstract: A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.Type: GrantFiled: January 30, 2020Date of Patent: October 25, 2022Assignees: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED, LIFE TECHNOLOGIES CORPORATIONInventors: Kuan Moon Boo, Wei Fuh Teo, Zeqi Tan, Soo Yong Lau, Ming Tiong Sia, Woon Liang Soh, Ching Yee Lam, Shan Hua Dong, Marc Haberstroh, Michael C. Pallas, Hardeep Sangha
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Patent number: 11339425Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lends can be a bi-convex lens.Type: GrantFiled: April 12, 2019Date of Patent: May 24, 2022Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Jacob K. Freudenthal, Geoffrey Dahlhoff, Kevin Maher, Ming Song Chen, Gary Lim, Ronald Danehy, David Fortescue, Ming Shen, Woon Liang Soh, Francis T. Cheng, Ruoyun Wu, Thiam Chye Lee, Gary A. Chappell, Chee Kiong Lim, Jeff Dere, Ted Straub, Jorge Fonseca, Kuan Moon Boo, Soo Yong Lau
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Publication number: 20210214771Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.Type: ApplicationFiled: January 18, 2021Publication date: July 15, 2021Inventors: Mingsong CHEN, Kuan Moon BOO, Tiong Han TOH, Mauro AGUANNO, Soo Yong LAU, Huei YEO, Wei Fuh TEO
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Publication number: 20200241023Abstract: A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.Type: ApplicationFiled: January 30, 2020Publication date: July 30, 2020Inventors: Kuan Moon BOO, Wei Fuh TEO, Zeqi TAN, Soo Yong LAU, Ming Tiong SIA, Woon Liang SOH, Ching Yee LAM, Shan Hua DONG, Marc HABERSTROH, Michael C. PALLAS, Hardeep Sangha
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Publication number: 20200101461Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.Type: ApplicationFiled: September 26, 2019Publication date: April 2, 2020Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Chee Kiong LIM, Way Xuang LEE, Wuh Ken LOH, Chee Wee CHING, Chin Yong KOO, Siew Ying KOH, Tiong Han TOH, Kuan Moon BOO, Soo Yong LAU
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Patent number: 10471431Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.Type: GrantFiled: February 4, 2015Date of Patent: November 12, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Chee Kiong Lim, Way Xuang Lee, Wuh Ken Loh, Chee Wee Ching, Chin Yong Koo, Siew Ying Koh, Tiong Han Toh, Kuan Moon Boo, Soo Yong Lau
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Publication number: 20190300936Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lends can be a bi-convex lens.Type: ApplicationFiled: April 12, 2019Publication date: October 3, 2019Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jacob K. FREUDENTHAL, Geoffrey DAHLHOFF, Kevin MAHER, Ming Song CHEN, Gary LIM, Ronald DANEHY, David FORTESCUE, Ming SHEN, Woon Liang Soh, Francis T. CHENG, Ruoyun WU, Thiam Chye LEE, Gary A. CHAPPELL, Chee Kiong LIM, Jeff DERE, Ted E. STRAUB, Jorge FONSECA, Kuan Moon BOO, Soo Yong LAU
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Publication number: 20190193081Abstract: A thermal cycler is provided. The thermal cycler comprises a tray assembly. The tray assembly comprises a main body made of a first material having a first thermal conductivity. The tray assembly further comprises an adaptor made of a second material having a thermal conductivity that is greater than the thermal conductivity of the first material. The thermal cycler also includes a control block configured to control the temperature of the one or more nucleotide samples. The thermal cycler further includes a thermal cover sized and positioned to at least partially cover the plurality of vessels. The thermal cycler further includes a sample block including one or more depressions configured to receive a plurality of vessels containing one or more nucleotide samples.Type: ApplicationFiled: December 20, 2018Publication date: June 27, 2019Inventors: Huei Steven YEO, Soo Yong LAU, Cong JIANG
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Patent number: 10323274Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.Type: GrantFiled: September 28, 2012Date of Patent: June 18, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Jacob K. Freudenthal, Kevin Maher, Ming Song Chen, Theodore E. Straub, Kuan Moon Boo, Soo Yong Lau
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Publication number: 20190126281Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: August 29, 2018Publication date: May 2, 2019Inventors: Yong CHU, Jeffrey MARKS, Jacob FREUDENTHAL, Mingsong CHEN, Tiong Han TOH, Mauro AGUANNO, Lik Seng LAU, Lian Seng LOH, Kok Siong TEO, Zeng Wei CHU, Xin MATHERS, Michael UY, Huei Steven YEO, Kuan Moon BOO, Way Xuang LEE, Chin Yong KOO, Wei Fuh TEO, Soo Yong LAU, Hon Siu SHIN, Zeqi TAN, Thomas WESSEL, David WOO
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Patent number: 10159982Abstract: A thermal cycler is provided. The thermal cycler comprises a tray assembly. The tray assembly comprises a main body made of a first material having a first thermal conductivity. The tray assembly further comprises an adaptor made of a second material having a thermal conductivity that is greater than the thermal conductivity of the first material. The thermal cycler also includes a control block configured to control the temperature of the one or more nucleotide samples. The thermal cycler further includes a thermal cover sized and positioned to at least partially cover the plurality of vessels. The thermal cycler further includes a sample block including one or more depressions configured to receive a plurality of vessels containing one or more nucleotide samples.Type: GrantFiled: December 8, 2011Date of Patent: December 25, 2018Assignee: Applied Biosystems B.V.Inventors: Huei Yeo, Soo Yong Lau, Cong Jiang
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Publication number: 20170307529Abstract: An instrument for processing and/or measuring a biological process contains an excitation source, a sample holder, an optical sensor, an excitation optical system, and an emission optical system. The sample holder is configured to receive a plurality of biological samples. The optical sensor is configured to receive an emission from the biological samples. The excitation optical system is disposed along an excitation optical path and is configured to direct the electromagnetic radiation from the excitation source to the biological samples. The emission optical system is disposed along an emission optical path and is configured to direct electromagnetic emissions from the biological samples to the optical sensor. The instrument further contains a plurality of filter assemblies configured to be interchangeably located along at least one of the optical paths.Type: ApplicationFiled: July 7, 2017Publication date: October 26, 2017Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Kevin MAHER, Mingsong CHEN, Jacob K. FREUDENTHAL, Kuan Moon BOO, Soo Yong LAU, David FORTESCUE, Ming SHEN, Woon Liang Terence SOH
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Patent number: 9702823Abstract: An instrument for processing and/or measuring a biological process contains an excitation source, a sample holder, an optical sensor, an excitation optical system, and an emission optical system. The sample holder is configured to receive a plurality of biological samples. The optical sensor is configured to receive an emission from the biological samples. The excitation optical system is disposed along an excitation optical path and is configured to direct the electromagnetic radiation from the excitation source to the biological samples. The emission optical system is disposed along an emission optical path and is configured to direct electromagnetic emissions from the biological samples to the optical sensor. The instrument further contains a plurality of filter assemblies configured to be interchangeably located along at least one of the optical paths.Type: GrantFiled: September 28, 2012Date of Patent: July 11, 2017Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Kevin Maher, Mingsong Chen, Jacob Freudenthal, Kuan Moon Boo, Soo Yong Lau, David Fortescue, Ming Shen, Woon Liang Terence Soh
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Publication number: 20160228876Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: February 5, 2016Publication date: August 11, 2016Inventors: Yong Chu, Jeffrey Marks, Jacob Freudenthal, Mingsong Chen, Tiong Han Toh, Mauro Aguanno, Lik Seng Lau, Lian Seng Loh, Kok Siong Teo, Zeng Wei Chu, Xin Mathers, Michael Uy, Huei Yeo, Kuan Moon Boo, Way Xuang Lee, Chin Yong Koo, Wei Fuh Teo, Soo Yong Lau, Hon Siu Shin, Zeqi Tan, Thomas Wessel, Woo David