Patents by Inventor Soohee Lee

Soohee Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250075187
    Abstract: The present invention relates to a medium composition for preparing an intestinal organoid. In addition, the present invention relates to: a method for preparing an intestinal organoid, comprising a step of culturing using the medium composition; and an intestinal organoid prepared by the preparation method. The medium for preparing an intestinal organoid can promote the proliferation of the intestinal organoid and maintain the stemness of the intestinal organoid. Therefore, the medium can be used in preparing a large amount of intestinal organoids of excellent quality, and intestinal organoids prepared using the medium can be used as agents for preventing or treating intestine-associated diseases, alternatives to animal experimental models of intestine-associated diseases, and the like.
    Type: Application
    Filed: November 11, 2022
    Publication date: March 6, 2025
    Applicant: ORGANOIDSCIENCES LTD.
    Inventors: Hyokyung LEE, Soohee CHOI, Eunseo KANG, Ji Hye TAK, Jun-Hyeok PARK, Yong-II KIM
  • Publication number: 20250023192
    Abstract: A separator for a rechargeable lithium battery and a rechargeable lithium battery including the same, the separator includes a substrate; and a coating layer on at least one surface of the substrate, wherein the coating layer includes cube-shaped inorganic particles having a D50 particle diameter of greater than or equal to about 0.15 ?m and less than about 0.4 ?m, and a D99 particle diameter of greater than or equal to about 0.4 ?m and less than or equal to about 1.0 ?m, and the coating layer has a thickness of greater than 0 ?m and less than about 2.0 ?m.
    Type: Application
    Filed: January 22, 2024
    Publication date: January 16, 2025
    Inventors: Jungyoon Lee, Soohee Kim, Changhong Ko, Sam-Jin Park, Jinweon Seo
  • Patent number: 6063592
    Abstract: A method for cleaving polypeptides includes contacting a polypeptide with a recombinant or isolated Kell protein having proteolytic activity for the polypeptide. A method for converting big endothelins-1, -2 and -3 to endothelins-1, -2 and -3 respectively comprises contacting the big endothelin with Kell protein having proteolytic activity for cleaving big endothelin-1, -2 and -3 to endothelin-1, -2 or -3 respectively. In another embodiment, the Kell protein cleaves vasoactive intestinal peptide.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: May 16, 2000
    Assignee: New York Blood Center, Inc.
    Inventor: Soohee Lee
  • Patent number: 5804379
    Abstract: The invention provides a diagnostic method of determining Kell genotype by the identification of the molecular basis of a Kell polymorphism. Specifically, the invention provides a method for determining K1/K2 genotype with great accuracy, overcoming problems associated with traditional serological typing methods. The diagnostic method of the invention preferably employs amplification of K1/K2 nucleic acid sequences, and optionally employs differential cleavage of K1- and K2-specific nucleic acid sequences by a restriction enzyme. Also provided are nucleic acid oligomers useful as probes or primers for the method of the invention. Furthermore, diagnostic kits for the determination of Kell genotype are provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 8, 1998
    Assignee: New York Blood Center, Inc.
    Inventors: Soohee Lee, Colvin M. Redman
  • Patent number: 5589336
    Abstract: The invention provides a diagnostic method of determining Kell genotype by the identification of the molecular basis of a Kell polymorphism. Specifically, the invention provides a method for determining K1/K2 genotype with great accuracy, overcoming problems associated with traditional serological typing methods. The diagnostic method of the invention preferably employs amplification of K1/K2 nucleic acid sequences, and optionally employs differential cleavage of K1- and K2-specific nucleic acid sequences by a restriction enzyme. Also provided are nucleic acid oligomers useful as probes or primers for the method of the invention. Furthermore, diagnostic kits for the determination of Kell genotype are provided.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: December 31, 1996
    Assignee: New York Blood Center
    Inventors: Soohee Lee, Colvin Redman