Abstract: Provided is a chemical storage apparatus including a reservoir including a chemical tank configured to store a chemical, a first fixing member disposed on an upper surface of the chemical tank, and a second fixing member disposed on a lower surface of the chemical tank, a sensor configured to measure a specific parameter of the chemical stored in the reservoir, a receptacle having a space in which the sensor is accommodated, and coupling members for attaching or detaching the receptacle to or from the first fixing member and the second fixing member, respectively.

Abstract: A computing system may include a circuit design access engine configured to access a circuit design. The computing system may also include a duplicate section processing engine configured to partition the circuit design into multiple circuit sections and determine, from among the multiple circuit sections, an identical section set based on duplicate criteria. Circuit sections of the identical section set may satisfy the duplicate criteria with respect to one another. The duplicate section processing engine may further be configured to perform an OPC processing operation on a selected circuit section of the identical section set and apply an OPC result of the performed OPC processing operation for other circuit sections of the identical section set instead of or without performing the OPC processing operation on the other circuit sections of the identical section set.

Abstract: According to one aspect, a medical device may be configured to couple to a body. The medical device may comprise a material layer; a plurality of adhesive layers coupled to the material layer and configured to couple to a user's skin, wherein each adhesive layer of the plurality of adhesive layers includes a plurality of micro passages; a channel extending between two adjacent adhesive layers of the plurality of adhesive layers; and a superhydrophobic coating covering at least a portion of each of the two adjacent adhesive layers and the material layer forming the channel.

Abstract: The microfluidic devices and systems disclosed herein reduce sample loss and help decrease sample processing bottlenecks for applications such as next generation sequencing (NGS). The microfluidic devices include a plurality of reaction modules. Each reaction module may comprise one or more reaction circuits. Each reaction circuit may comprise a single reaction flow channel with each reaction circuit connected by a bridge flow channel. Alternatively, each reaction circuit may comprise two or more reaction flow channels connected by two or more bridge flow channels. The combination of any two bridge flow channels and a portion of the two or more reaction flow channels between the any two bridge flow channels defining may define the reaction circuit. The reaction module may be arranged as nodes connected by bridge flow channels or each reaction module may be arranged in a parallel fashion on the microfluidic device.

Abstract: A lateral flow diagnostic testing apparatus including a measurement assembly in which a cartridge is loaded and which is inclined with respect to a main body housing in a lateral flow direction of the cartridge is disclosed. The main body housing and the measurement assembly is rotatably hinge-coupled to adjust an inclination angle. The inclination of the measurement assembly is adjustable by an inclination driving unit. A vibration actuator can be further included on a cartridge loading surface. In addition, a heating unit fixed to face the cartridge can be further included.

Abstract: A computing system may include a circuit design access engine configured to access a circuit design. The computing system may also include a duplicate section processing engine configured to partition the circuit design into multiple circuit sections and determine, from among the multiple circuit sections, an identical section set based on duplicate criteria. Circuit sections of the identical section set may satisfy the duplicate criteria with respect to one another. The duplicate section processing engine may further be configured to perform an OPC processing operation on a selected circuit section of the identical section set and apply an OPC result of the performed OPC processing operation for other circuit sections of the identical section set instead of or without performing the OPC processing operation on the other circuit sections of the identical section set.

Abstract: The microfluidic devices and systems disclosed herein reduce sample loss and help decrease sample processing bottlenecks for applications such as next generation sequencing (NGS). The microfluidic devices include a plurality of reaction modules. Each reaction module may comprise one or more reaction circuits. Each reaction circuit may comprise a single reaction flow channel with each reaction circuit connected by a bridge flow channel. Alternatively, each reaction circuit may comprise two or more reaction flow channels connected by two or more bridge flow channels. The combination of any two bridge flow channels and a portion of the two or more reaction flow channels between the any two bridge flow channels defining may define the reaction circuit. The reaction module may be arranged as nodes connected by bridge flow channels or each reaction module may be arranged in a parallel fashion on the microfluidic device.

Abstract: A lateral flow diagnostic testing apparatus including a measurement assembly in which a cartridge is loaded and which is inclined with respect to a main body housing in a lateral flow direction of the cartridge is disclosed. The main body housing and the measurement assembly is rotatably hinge-coupled to adjust an inclination angle. The inclination of the measurement assembly is adjustable by an inclination driving unit. A vibration actuator can be further included on a cartridge loading surface. In addition, a heating unit fixed to face the cartridge can be further included.

Abstract: Most somatic mutations are harmless, but some lead to a phenotypic consequence. The present invention provides methods and tools to elucidate exactly how mutations appear in the genome using detection of mutations in a cell lineage. The present invention also provides for determining the effect of environmental stimuli and drugs on somatic mutations. Finally, the present invention provides for personalized medicine by determining the effect of drugs on somatic mutations in cells obtained from a subject in need thereof.

Abstract: Provided are an image display apparatus and an operating method of the same. The image display apparatus includes a display displaying image content, a memory storing one or more instructions; and a processor configured to execute the one or more instructions stored in the memory, and the processor is configured to execute the one or more instructions to acquire actual size information of at least one object included in the image content and to control the display to display the at least one object in its actual size based on the actual size information.

Abstract: The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane; A microfluidic circuit including one or more sieve valves. In particular embodiments, the circuit comprises one or more input/output valves. The one or one or more input/output valves can include one or more input valves and one or more output valves. The microfluidic circuit can further include a mixing circuit. At least one of the sieve valves can be positioned between the one or more input/output valves and the mixing circuit. The invention further provides methods of using the device for the analysis of samples comprising cells.

Abstract: The microfluidic devices and systems disclosed herein reduce sample loss and help decrease sample processing bottlenecks for applications such as next generation sequencing (NGS). The microfluidic devices include a plurality of reaction modules. Each reaction module may comprise one or more reaction circuits. Each reaction circuit may comprise a single reaction flow channel with each reaction circuit connected by a bridge flow channel. Alternatively, each reaction circuit may comprise two or more reaction flow channels connected by two or more bridge flow channels. The combination of any two bridge flow channels and a portion of the two or more reaction flow channels between the any two bridge flow channels defining may define the reaction circuit. The reaction module may be arranged as nodes connected by bridge flow channels or each reaction module may be arranged in a parallel fashion on the microfluidic device.

Abstract: The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane; A microfluidic circuit including one or more sieve valves. In particular embodiments, the circuit comprises one or more input/output valves. The one or one or more input/output valves can include one or more input valves and one or more output valves. The microfluidic circuit can further include a mixing circuit. At least one of the sieve valves can be positioned between the one or more input/output valves and the mixing circuit. The invention further provides methods of using the device for the analysis of samples comprising cells.

Abstract: The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane; A microfluidic circuit including one or more sieve valves. In particular embodiments, the circuit comprises one or more input/output valves. The one or one or more input/output valves can include one or more input valves and one or more output valves. The microfluidic circuit can further include a mixing circuit. At least one of the sieve valves can be positioned between the one or more input/output valves and the mixing circuit. The invention further provides methods of using the device for the analysis of samples comprising cells.

Abstract: The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane; A microfluidic circuit including one or more sieve valves. In particular embodiments, the circuit comprises one or more input/output valves. The one or one or more input/output valves can include one or more input valves and one or more output valves. The microfluidic circuit can further include a mixing circuit. At least one of the sieve valves can be positioned between the one or more input/output valves and the mixing circuit. The invention further provides methods of using the device for the analysis of samples comprising cells.

Abstract: Various embodiments identify some constraints for multiple mask designs of multi-patterning lithography processes for manufacturing an electronic design and colors multiple routing tracks in a layer of the electronic design with certain colors. These embodiments color fixed object(s) in the design with one or more of these certain colors based on coloring of the multiple routing tracks. Some embodiments further color movable object(s) based on results of coloring the fixed object(s) or coloring routing track(s). Some embodiments route the physical design with coloring of fixed object(s), coloring of movable object(s), or routing connectivity. Multiple-patterning conflicts may be detected based on the coloring of fixed object(s), coloring of movable object(s), or routing connectivity. Some embodiments route with search-and-repair strategy(ies) to improve or resolve conflict(s). Some embodiments color objects upon their creation, and the layout is thus multiple-patterning design rule clean as constructed.

Abstract: Techniques are described which decrease DRC (design rule check) marking time, e.g., in a circuit interconnect router, by capitalizing on repetitious relationships between interconnect elements (and/or circuit components) in a circuit design, by recording previously calculated markings and reusing the markings on subsequent marking iterations or processes. Marking information corresponding to each marking point includes indications of what types of interconnect elements or circuit components can be positioned at the marking point location without violating a design rule. With a dynamic caching process, once the marking computations have been completed for an element and the corresponding points in the vicinity, those values are stored in a cache. The next time the router encounters another instance of a known element-to-point relationship, the stored values are reloaded and applied to the current point.

Abstract: Techniques are described which decrease DRC (design rule check) marking time, e.g., in a circuit interconnect router, by capitalizing on repetitious relationships between interconnect elements (and/or circuit components) in a circuit design, by recording previously calculated markings and reusing the markings on subsequent marking iterations or processes. Marking information corresponding to each marking point includes indications of what types of interconnect elements or circuit components can be positioned at the marking point location without violating a design rule. With a dynamic caching process, once the marking computations have been completed for an element and the corresponding points in the vicinity, those values are stored in a cache. The next time the router encounters another instance of a known element-to-point relationship, the stored values are reloaded and applied to the current point.