Patents by Inventor Sophia George Antimisiaris

Sophia George Antimisiaris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liposomes containing particulate materials
    Patent number: 6451338
    Abstract: A method is provided for the formation of liposomes of 0.1 &mgr;m to 50 &mgr;m in diameter having unilamella or multilamella structure and containing water insoluble or undissolved particulate materials comprising (a) forming liposomes and removing substantially all of any organic solvent used in their preparation, (b) freeze drying the liposomes so formed and then (c) rehydrating them in intimate admixture with the particulate material. Preferred encapsulated materials are particulate materials, most preferably microorganisms, plant or animal cells or water insoluble structures having organic solvent labile biochemical or immunological activity, but any water insoluble particulate may be encapsulated using the method. For example catalysts or drugs that are sparingly soluble may also be so incorporated such that slow release into the a patients body may be provided while release of detergents included in the many liposome preparation protocols may be avoided.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: September 17, 2002
    Assignee: The Secretary of State for Defence in Her Britannic Majest's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: Gregory Gregoriadis, Sophia George Antimisiaris, Ishan Gursel
  • Liposomes containing particulate materials
    Publication number: 20020041895
    Abstract: A method is provided for the formation of liposomes of 0.1 &mgr;m to 50 &mgr;m in diameter having unilamella or multilamella structure and containing water insoluble or undissolved particulate materials comprising (a) forming liposomes and removing substantially all of any organic solvent used in their preparation, (b) freeze drying the liposomes so formed and then (c) rehydrating them in intimate admixture with the particulate material.
    Type: Application
    Filed: September 27, 2001
    Publication date: April 11, 2002
    Applicant: Unite Kingdom Defence Evaluation and Research Agency.
    Inventors: Gregory Gregoriadis, Sophia George Antimisiaris, Ishan Gursel
  • Liposomes containing particulate materials
    Patent number: 6322809
    Abstract: A method is provided for the formation of liposomes of 0.1 &mgr;m to 50 &mgr;m in diameter having unilamella or multilamella structure and containing water insoluble or undissolved particulate materials comprising (a) forming liposomes and removing substantially all of any organic solvent used in their preparation, (b) freeze drying the liposomes so formed and then (c) rehydrating them in intimate admixture with the particulate material. Preferred encapsulated materials are particulate materials, most preferably microorganisms, plant or animals cells or water insoluble structures having organic solvent labile biochemical or immunological activity, but any water insoluble particulate may be encapsulated using the method. For example, catalysts or drugs that are sparingly soluble may also be so incorporated such that slow release into the patient's body may be provided while release of detergents included in the many lipoome preparation protocols may be avoided.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: November 27, 2001
    Assignee: The Secretary of State for Defence in Her Brittanic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: Gregory Gregoriadis, Sophia George Antimisiaris, Ihsan Gursel