Patents by Inventor Sophia Mundle

Sophia Mundle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN METAPNEUMOVIRUS VACCINES
    Publication number: 20230310571
    Abstract: The present disclosure provides antigenic prefusion hMPV F polypeptides, nucleic acid sequences (e.g., RNA sequences, e.g., mRNA sequences) encoding prefusion hMPV F polypeptides, compositions comprising antigenic prefusion hMPV F polypeptides, compositions comprising nucleic acid sequences encoding prefusion hMPV F polypeptides, and hMPV vaccines.
    Type: Application
    Filed: November 29, 2022
    Publication date: October 5, 2023
    Inventors: Yvonne Chan, Sukanya Sasmal, Antonia Stuebler, Michael Kishko, Sophia Mundle, Linong Zhang, Josh DiNapoli, Judith Alamares-Sapuay, Natalie Anosova, Sudha Chivukula, Hillary Danz, Tod Strugnell, Rachel Groppo
  • HERPESVIRUS COMPOSITIONS AND RELATED METHODS
    Publication number: 20220133881
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compostions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Application
    Filed: January 14, 2022
    Publication date: May 5, 2022
    Inventors: Stephen ANDERSON, Simon DELAGRAVE, John HAMBERGER, Qinglian LI, Sophia MUNDLE, Nausheen RAHMAN
  • Herpesvirus compositions and related methods
    Patent number: 11260123
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable exctpients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: March 1, 2022
    Assignees: SANOFI PASTEUR LIMITED, SANOFI PASTEUR BIOLOGICS, LLC
    Inventors: Stephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
  • Purification of herpes virus
    Patent number: 11224650
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 18, 2022
    Assignee: SANOFI PASTEUR BIOLOGICS, LLC
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave
  • PURIFICATION OF HERPES VIRUS
    Publication number: 20190328866
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Application
    Filed: July 8, 2019
    Publication date: October 31, 2019
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave
  • Purification of herpes virus
    Patent number: 10363304
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: July 30, 2019
    Assignee: SANOFI PASTEUR BIOLOGICS, LLC
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave
  • PURIFICATION OF HERPES VIRUS
    Publication number: 20160331832
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Application
    Filed: May 16, 2016
    Publication date: November 17, 2016
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave
  • Purification of herpes virus
    Patent number: 9365832
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: June 14, 2016
    Assignee: SANOFI PASTEUR BIOLOGICS, LLC
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave
  • HERPESVIRUS COMPOSITIONS AND RELATED METHODS
    Publication number: 20150150964
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Application
    Filed: May 21, 2013
    Publication date: June 4, 2015
    Inventors: Stephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
  • PURIFICATION OF FLAVIVIRUSES
    Publication number: 20150030565
    Abstract: The present invention provides a method to prepare purified enveloped (e.g., flavivirus) viral particle preparations employing ion exchange chromatography and tangential flow filtration.
    Type: Application
    Filed: January 8, 2013
    Publication date: January 29, 2015
    Applicant: Sanofi Pasteur Biologics, LLC
    Inventors: Sophia Mundle, Stephen Anderson
  • PURIFICATION OF HERPES VIRUS
    Publication number: 20150004195
    Abstract: The present disclosure provides a method to prepare purified enveloped viral particle preparations employing ion ex change chromatography and tangential flow filtration.
    Type: Application
    Filed: January 9, 2013
    Publication date: January 1, 2015
    Inventors: Sophia Mundle, Stephen Anderson, Simon Delagrave