Patents by Inventor Sophie Andree Lelièvre

Sophie Andree Lelièvre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ultrasonic device
    Patent number: 11561202
    Abstract: The present disclosure relates to an ultrasonic device for real-time and nondestructive assessment of extracellular matrix stiffness, and the method of making and using the novel ultrasonic device.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: January 24, 2023
    Assignee: Purdue Research Foundation
    Inventors: Rahim Rahimi, Sophie Andree Lelievre, Amin Zareei, Shirisha Chittiboyina
  • ULTRASONIC DEVICE
    Publication number: 20210382012
    Abstract: The present disclosure relates to an ultrasonic device for real-time and nondestructive assessment of extracellular matrix stiffness, and the method of making and using the novel ultrasonic device.
    Type: Application
    Filed: March 8, 2021
    Publication date: December 9, 2021
    Applicant: Purdue Research Foundation
    Inventors: Rahim Rahimi, Sophie Andree Lelievre, Amin Zareei, Shirisha Chittiboyina
  • Gradient-on-a-chip
    Patent number: 10940475
    Abstract: Disclosed herein is a cell culture device and its applications of creating gradient of chemicals or gradient of cells to mimic the in vivo physiological conditions of homeostasis.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: March 9, 2021
    Assignee: Purdue Research Foundation
    Inventors: Sophie Andree Lelièvre, Babak Ziaie, Manuel P. Ochoa, Rahim Rahimi, Farzaneh Atrian, Shirisha Chittiboyina
  • MACROTUMOR ENGINEERING
    Publication number: 20200399589
    Abstract: A collagen-fibronectin-based method enables the production of tumors of centimeter size with recognizable pathological traits. The method supports reproducing tumor heterogeneity with preinvasive and invasive phenotypes and stacking of tumor portions using a paper-scaffold with 80 ?m-punched holes for larger nodule creation and easy separation of tumor portions for analysis. Macrotumors are convenient for testing drug delivery and therapeutic tools that necessitate a minimum tumor size relevant to in vivo.
    Type: Application
    Filed: June 9, 2020
    Publication date: December 24, 2020
    Applicant: Purdue Research Foundation
    Inventors: Sophie Andree Lelievre, Rahim Rahimi, Tim Kwok
  • GRADIENT-ON-A-CHIP
    Publication number: 20180280976
    Abstract: Disclosed herein is a cell culture device and its applications of creating gradient of chemicals or gradient of cells to mimic the in vivo physiological conditions of homeostasis.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: Purdue Research Foundation
    Inventors: Sophie Andree Lelièvre, Babak Ziaie, Manuel P. Ochoa, Rahim Rahimi, Farzaneh Atrian, Shirisha Chittiboyina
  • Disease-on-a-chip
    Patent number: 9969964
    Abstract: The invention generally relates to a cell culture system for coculturing non-neoplastic and neoplastic cells on a planar member which more faithfully mimics the in vivo geometry of a lumen or a cavity.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 15, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Sophie Andree Lelievre, Pierre-Alexandre Vidi, James Francis Leary, Teimour Maleki-Jafarabadi
  • Disease-on-a-Chip
    Publication number: 20150177226
    Abstract: The invention generally relates to a cell culture system for coculturing non-neoplastic and neoplastic cells on a planar member which more faithfully mimics the in vivo geometry of a lumen or a cavity.
    Type: Application
    Filed: December 19, 2014
    Publication date: June 25, 2015
    Applicant: Purdue Research Foundation
    Inventors: Sophie Andree Lelievre, Pierre-Alexandre Vidi, James Francis Leary, Teimour Maleki-Jafarabadi