Patents by Inventor Sophie Eva Bogdan

Sophie Eva Bogdan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-(2-imidazolinylamino)-benzimidazole derivatives, their preparation and their use as .alpha.-adrenoceptor agonists with improved metabolic stability
    Patent number: 6486190
    Abstract: Benzimidazole compounds having the generic structure: are used to treat alpha-2 mediated disorders, including nasal congestion, glaucoma, asthma, migraine, and diarrhea.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: November 26, 2002
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Nick Nikolaides, Sheri Ann Gilbert, Michael Gazda, Roy Lee Dobson, Charles Andrew III Cruze
  • Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Publication number: 20020128481
    Abstract: This invention involves compounds having the following structure: 1
    Type: Application
    Filed: February 8, 2002
    Publication date: September 12, 2002
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinylamino heterocycle compounds useful as &agr;-2 adrenoceptor agonists
    Patent number: 6436978
    Abstract: This invention involves compounds having the following structure: as described in the Claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: August 20, 2002
    Assignee: The Procter & Gamble Co.
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Publication number: 20020095039
    Abstract: This invention involves compounds having the following structure: 1
    Type: Application
    Filed: December 14, 2001
    Publication date: July 18, 2002
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Patent number: 6391878
    Abstract: This invention involves compounds having the following structure: as described in the Claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: May 21, 2002
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinylamino heterocycle compunds useful as alpha-2 adrenoceptor agonists
    Publication number: 20020028950
    Abstract: This invention involves compounds having the following structure: 1
    Type: Application
    Filed: July 31, 2001
    Publication date: March 7, 2002
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Patent number: 6306877
    Abstract: This invention involves compounds having the following structure as described in the Claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: October 23, 2001
    Assignee: The Procter & Gamble Co.
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Patent number: 6225331
    Abstract: This invention involves compounds having the following structure: as described in the claims; and enantiomers, optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmaceutical compositions comprising such novel compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: May 1, 2001
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Publication number: 20010000345
    Abstract: This invention involves compounds having the following structure: 1
    Type: Application
    Filed: December 1, 2000
    Publication date: April 19, 2001
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
    Patent number: 6172095
    Abstract: This invention involves compounds having the structure (I) as described in the claims, and enantiomers,optical isomers, stereoisomers, diastereomers, tautomers, addition salts, biohydrolyzable amides and esters thereof, as well as pharmaceutical compositions comprising such noved compounds. The invention also relates to the use of such compounds for preventing or treating disorders modulated by alpha-2 adrenoceptors.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: January 9, 2001
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan, Raymond Todd Henry, Russell James Sheldon, William Lee Seibel, Jeffrey Joseph Ares
  • 7-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
    Patent number: 5716966
    Abstract: The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: ##STR1## wherein: (a) R is unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; and(b) R' is selected from hydrogen; unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; unsubstituted C.sub.1 -C.sub.3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo.The subject invention also involves the use of such compounds for preventing or treating other respiratory, ocular and/or gastrointestinal disorders. The subject invention also involves novel compounds having the above structure wherein R' is hydrogen or fluoro or cyano.
    Type: Grant
    Filed: June 29, 1995
    Date of Patent: February 10, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan
  • 5-(2-imidazolinylamino)benzimidazole compounds useful as alpha-2-adrenoceptor agonists
    Patent number: 5691370
    Abstract: The subject invention involves compounds having the following structure: ##STR1## wherein: (a) R is unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl;(b) R' is selected from hydrogen; unsubstituted C.sub.1 -C.sub.3 alkanyl or alkenyl; unsubstituted C.sub.1 -C.sub.3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo; and(c) R" is selected from hydrogen, methyl, ethyl and i-propyl.The subject invention also involves pharmaceutical compositions containing such novel compounds, compositions thereof and the use of such compounds for preventing or treating respiratory, ocular and/or gastrointestinal disorders.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: November 25, 1997
    Assignee: The Procter & Gamble Company
    Inventors: Thomas Lee Cupps, Sophie Eva Bogdan