Patents by Inventor Sophie KHEM

Sophie KHEM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240013388
    Abstract: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
    Type: Application
    Filed: September 22, 2023
    Publication date: January 11, 2024
    Inventors: Timothy A. FONTE, Leo J. GRADY, Zhongle WU, Michiel SCHAAP, Stanley C. HUNLEY, Souma SENGUPTA, Sophie KHEM
  • Patent number: 11803965
    Abstract: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
    Type: Grant
    Filed: May 9, 2022
    Date of Patent: October 31, 2023
    Assignee: HeartFlow, Inc.
    Inventors: Timothy A. Fonte, Leo J. Grady, Zhongle Wu, Michiel Schaap, Stanley C. Hunley, Souma Sengupta, Sophie Khem
  • Publication number: 20230301720
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Application
    Filed: March 8, 2023
    Publication date: September 28, 2023
    Inventors: Leo John GRADY, Michiel SCHAAP, Sophie KHEM, Sarah WILKES, Ying BAI
  • Publication number: 20230277247
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Application
    Filed: April 21, 2023
    Publication date: September 7, 2023
    Inventors: Charles A. TAYLOR, Hyun Jin KIM, Sophie KHEM, Sethuraman SANKARAN, David SPAIN, Nan XIAO
  • Patent number: 11660143
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: May 30, 2023
    Assignee: HeartFlow, Inc.
    Inventors: Charles A. Taylor, Hyun Jin Kim, Sophie Khem, Sethuraman Sankaran, David Spain, Nan Xiao
  • Patent number: 11622812
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: April 11, 2023
    Assignee: HeartFlow, Inc.
    Inventors: Leo Grady, Michiel Schaap, Sophie Khem, Sarah Wilkes, Ying Bai
  • Patent number: 11494904
    Abstract: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: November 8, 2022
    Assignee: HeartFlow, Inc.
    Inventors: Timothy A. Fonte, Leo Grady, Zhongle Wu, Michiel Schaap, Stanley C. Hunley, Souma Sengupta, Sophie Khem
  • Publication number: 20220277446
    Abstract: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
    Type: Application
    Filed: May 9, 2022
    Publication date: September 1, 2022
    Inventors: Timothy A. FONTE, Leo J. GRADY, Zhongle WU, Michiel SCHAAP, Stanley C. HUNLEY, Souma SENGUPTA, Sophie KHEM
  • Publication number: 20220079681
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Application
    Filed: November 24, 2021
    Publication date: March 17, 2022
    Inventors: Leo GRADY, Michiel SCHAAP, Sophie KHEM, Sarah WILKES, Ying BAI
  • Patent number: 11213354
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: January 4, 2022
    Assignee: HeartFlow, Inc.
    Inventors: Leo Grady, Michiel Schaap, Sophie Khem, Sarah Wilkes, Ying Bai
  • Publication number: 20210196391
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Application
    Filed: March 10, 2021
    Publication date: July 1, 2021
    Inventors: Charles A. TAYLOR, Hyun Jin KIM, Sophie KHEM, Sethuraman SANKARAN, David SPAIN, Nan XIAO
  • Patent number: 10973583
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: April 13, 2021
    Assignee: HeartFlow, Inc.
    Inventors: Charles A. Taylor, Hyun Jin Kim, Sophie Khem, Sethuraman Sankaran, David Spain, Nan Xiao
  • Patent number: 10939828
    Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: March 9, 2021
    Assignee: HeartFlow, Inc.
    Inventors: Timothy A. Fonte, Charles A. Taylor, Hyun Jin Kim, Sophie Khem
  • Publication number: 20200268451
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Application
    Filed: May 11, 2020
    Publication date: August 27, 2020
    Applicant: HeartFlow, Inc.
    Inventors: Leo GRADY, Michiel SCHAAP, Sophie KHEM, Sarah WILKES, Ying BAI
  • Patent number: 10682183
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: June 16, 2020
    Assignee: HeartFlow, Inc.
    Inventors: Leo Grady, Michiel Schaap, Sophie Khem, Sarah Wilkes, Ying Bai
  • Publication number: 20200085502
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Charles A. TAYLOR, Hyun Jin KIM, Sophie KHEM, Sethuraman SANKARAN, David Spain, Nan XIAO
  • Patent number: 10517678
    Abstract: Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: December 31, 2019
    Assignee: HeartFlow, Inc.
    Inventors: Charles A. Taylor, Hyun Jin Kim, Sophie Khem, Sethuraman Sankaran, David Spain, Nan Xiao
  • Publication number: 20180140258
    Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 24, 2018
    Inventors: Timothy A. FONTE, Charles A. TAYLOR, Hyun Jin KIM, Sophie KHEM
  • Patent number: 9974616
    Abstract: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: May 22, 2018
    Assignee: HeartFlow, Inc.
    Inventors: Leo Grady, Michiel Schaap, Sophie Khem, Sarah Wilkes, Ying Bai
  • Patent number: 9913616
    Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: March 13, 2018
    Assignee: HeartFlow, Inc.
    Inventors: Timothy A. Fonte, Charles A. Taylor, Hyun Jin Kim, Sophie Khem