Patents by Inventor Sophie Mehier-Humbert

Sophie Mehier-Humbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising gas-filled microcapsules for ultrasound mediated delivery
    Patent number: 9375397
    Abstract: Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: June 28, 2016
    Assignee: BRACCO SUISSE S.A.
    Inventors: Thierry Bettinger, Feng Yan, Sophie Mehier-Humbert, Peter Frinking
  • Composition Comprising Gas-Filled Microcapsules For Ultrasound Mediated Delivery
    Publication number: 20110208115
    Abstract: Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.
    Type: Application
    Filed: April 28, 2011
    Publication date: August 25, 2011
    Applicant: BRACCO RESEARCH S.A.
    Inventors: Thierry BETTINGER, Feng YAN, Sophie MEHIER-HUMBERT, Peter FRINKING
  • Composition comprising gas-filled microcapsules for ultrasound mediated delivery
    Publication number: 20090041833
    Abstract: Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.
    Type: Application
    Filed: April 11, 2006
    Publication date: February 12, 2009
    Applicant: Bracco Research S.A.
    Inventors: Thierry Bettinger, Feng Yan, Sophie Mehier-Humbert, Peter Frinking