Patents by Inventor Sophie PETROPOULOS

Sophie PETROPOULOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA METHYLATION SIGNATURES OF CANCER IN HOST PERIPHERAL BLOOD MONONUCLEAR CELLS AND T CELLS
    Publication number: 20220267862
    Abstract: A cancer has a DNA methylation signature in host T cells and Peripheral Blood Mononuclear Cells (PBMC) DNA. The present disclosure provides CG IDs derived from PBMC DNA for predicting hepatocellular carcinoma (HCC) stages and chronic hepatitis. Also disclosed are kits for predicting HCC using identified CG IDs and pyrosequencing DNA methylation assays, receiver operating characteristics (ROC) assays, penalized regression assays and hierarchical clustering analysis assays. The present disclosure provides DNA methylation signatures (CG IDs) that can be used for diagnosis, prognosis, and treatment of a cancer.
    Type: Application
    Filed: March 22, 2022
    Publication date: August 25, 2022
    Inventors: Moshe SZYF, Ning LI, Yonghong ZHANG, Sophie PETROPOULOS
  • DNA METHYLATION SIGNATURES OF CANCER IN HOST PERIPHERAL BLOOD MONONUCLEAR CELLS AND T CELLS
    Publication number: 20190345559
    Abstract: Disclosed is a DNA methylation signature in Peripheral Blood Mononuclear cells (PBMC) for predicting hepatocellular carcinoma (HCC) stages and chronic hepatitis, which is CG IDs. This invention also disclosed kits and uses for the DNA methylation signature.
    Type: Application
    Filed: June 23, 2016
    Publication date: November 14, 2019
    Applicants: Beijing Youan Hospital, Captical Medical University
    Inventors: Moshe SZYF, Ning LI, Yonghong ZHANG, Sophie PETROPOULOS