Patents by Inventor Sophie Poty

Sophie Poty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody-drug conjugates based on gold compounds
    Patent number: 11141490
    Abstract: Antibody-drug-conjugates (ADC) are provided having a structure of: wherein L is PR3 ligand. The ADC has n drug moieties bound to the Trastuzumab antibody such that the ADC has a drug-to-antibody ratio (DAR) between 2 and 4 and the drug moieties are bound to the Trastuzumab antibody through cysteine (S) or lystine (Lys) residues. The disclosed ADCs are particularly useful in treating breast cancer.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: October 12, 2021
    Assignees: Research Foundation of the City University of New York, Memorial Sloan Kettering Cancer Center
    Inventors: Maria Contel, Natalia Curado, Jason Lewis, Sophie Poty
  • ANTIBODY-DRUG CONJUGATES BASED ON GOLD COMPOUNDS
    Publication number: 20200016276
    Abstract: Antibody-drug-conjugates (ADC) are provided having a structure of: wherein L is PR3 ligand. The ADC has n drug moieties bound to the Trastuzumab antibody such that the ADC has a drug-to-antibody ratio (DAR) between 2 and 4 and the drug moieties are bound to the Trastuzumab antibody through cysteine (S) or lystine (Lys) residues. The disclosed ADCs are particularly useful in treating breast cancer.
    Type: Application
    Filed: July 5, 2019
    Publication date: January 16, 2020
    Inventors: Maria Contel, Natalia Curado, Jason Lewis, Sophie Poty