Patents by Inventor Sophie Robin

Sophie Robin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Unshrunken tissue equivalent and methods for producing such an unshrunken tissue equivalent
    Patent number: 8992613
    Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: March 31, 2015
    Assignees: Universite de Franche-Comte, Centre Hospitalier Universitaire de Besancon
    Inventors: Philippe Humbert, Delphine Binda, Celine Viennet-Steiner, Sophie Robin, Helene Tauzin, Gwenael Rolin, Lionel Pazart
  • UNSHRUNKEN TISSUE EQUIVALENT, SKIN EQUIVALENT COMPRISING SUCH AN UNSHRUNKEN TISSUE EQUIVALENT, AND METHODS FOR PRODUCING SUCH AN UNSHRUNKEN TISSUE EQUIVALENT AND SUCH A SKIN EQUIVALENT
    Publication number: 20120135520
    Abstract: The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular matrix; at least one pluridimensional medium is soaked with said mixture; from the components of the mixture, a lattice comprising at least one element of an extracellular matrix is produced, at least at the medium; at least part of the components of said mixture is attached to the structure of the medium; the shrinking of at least the lattice is prevented and at least said lattice is tensioned on said medium; fibroblasts are integrated into the lattice and at least one cell culture of said fibroblasts is carried out, at least in the lattice. The invention also relates to a method for producing a skin equivalent that comprises at least one dermal equivalent formed by an unshrunken tissue equivalent and at least one epidermal equivalent.
    Type: Application
    Filed: July 1, 2010
    Publication date: May 31, 2012
    Applicants: CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON, UNIVERSITE DE FRANCHE-COMTE
    Inventors: Philippe Humbert, Delphine Binda, Celine Viennet-Steiner, Sophie Robin, Helene Tauzin, Gwenael Rolin, Lionel Pazart
  • Polyalcoxyamines obtained from &bgr;-substituted nitroxides
    Patent number: 6657043
    Abstract: The invention relates to polyalcoxyamines obtained from beta-substituted nitroxides of formula (1) wherein A represents a di- or polyvalent structure, R1 represents a molar mass of more than 15 and is a monovalent radical, and n>2. The inventive compounds can be used as initiators for (co)polymerizations of at least one radically polymerizable monomer.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: December 2, 2003
    Assignee: Atofina
    Inventors: Olivier Guerret, Jean-Luc Couturier, Jean-Francois Lutz, Christophe Le Mercier, Sophie Robin, Bruno Vuillemin
  • Multimodal polymers by controlled radical polymerization in the presence of alkoxyamines
    Patent number: 6646079
    Abstract: For the preparation of a multimodal polymer at least one monomer is subjected to free radical polymerization in the presence of several alkoxyamines comprising the sequence of formula: in which RL is a monovalent radical exhibiting a molar mass of greater than 15, A represents the core of the alkoxyamine and n is a non-zero integer, the alkoxyamines exhibiting different values of n.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: November 11, 2003
    Assignee: Atofina
    Inventors: Olivier Guerret, Sophie Robin, Yves Gnanou
  • Radical polymerization in the presence of several stable free radicals
    Patent number: 6509428
    Abstract: The invention relates to a process for the radical polymerization of at least one monomer in the presence of at least two stable free radicals of different natures. The use of two different stable free radicals is reflected by a higher productivity than that which would be expected on calculating the arithmetic mean of the productivities obtained with each of the stable free radicals when they are used individually.
    Type: Grant
    Filed: October 6, 1999
    Date of Patent: January 21, 2003
    Assignee: Atofina
    Inventors: Thierry Senninger, Sophie Robin, Yves Gnanou
  • Multimodal polymers by controlled radical polymerization in the presence of alkoxyamines
    Publication number: 20020040117
    Abstract: For the preparation of a multimodal polymer at least one monomer is subjected to free radical polymerization in the presence of several alkoxyamines comprising the sequence of formula: 1
    Type: Application
    Filed: April 9, 2001
    Publication date: April 4, 2002
    Applicant: ATOFINA
    Inventors: Olivier Guerret, Sophie Robin, Yves Gnanou