Patents by Inventor Sophie Roy

Sophie Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COOLING OF BATTERY CELLS
    Publication number: 20240109458
    Abstract: A method of determines one or more voltage threshold values for controlling a cooling of battery cells. The method includes determining, during e.g. charging of the battery cells, a charging voltage threshold value for starting or increasing a battery cell cooling, corresponding to a voltage across a reference set of battery cells at which a rate of change of temperature with respect to voltage of the reference set goes above a charging temperature rate threshold value. A method for using such one or more voltage threshold values for controlling a cooling of the battery cells, by comparing a measured voltage across the battery cells against the voltage threshold value(s) is also provided.
    Type: Application
    Filed: September 26, 2023
    Publication date: April 4, 2024
    Applicant: VOLVO TRUCK CORPORATION
    Inventors: Istaq Ahmed, Alice Hamrin, Sophie Tintignac, Niladri Roy Chowdhury, Masood Tamadondar, Praveen Raju Hasbavi, Gustav Giske
  • ANTI-BCMA THERAPY IN AUTOIMMUNE DISORDERS
    Publication number: 20240052064
    Abstract: The present invention relates to the treatment or management of autoimmune disorders, such as autoimmune disorders caused by autoreactive B lineage cells, e.g. anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
    Type: Application
    Filed: February 11, 2021
    Publication date: February 15, 2024
    Inventors: Kofi MENSAH, Robert PLENGE, Sophie ROY, Dennis ZALLER, Jennifer DOVEY, Steven SAENZ, Jill HENAULT, Camille DOYKAN, Jenna CALVINO, Xi JIN, Joseph PAQUETTE
  • Irreversible caspase-3 inhibitors as active site probes
    Publication number: 20060069038
    Abstract: The present invention encompasses a compound of Formula (I) useful as caspase active site probes. These probes can be used to determine whether a caspase has been activated, in cells or in tissues of animal models of various pathologies. Furthermore, through competition based assays, these caspase active site probes can be used to calculate the percentage of occupancy of active caspases by other, unlabeled inhibitors.
    Type: Application
    Filed: February 5, 2004
    Publication date: March 30, 2006
    Inventors: John Colucci, Andre Giroux, Yongxin Han, Nathalie Methot, Donald Nicholson, Sophie Roy, John Vaillancourt, Paul Tawa
  • Autoantigenic fragments, methods and assays
    Publication number: 20050112137
    Abstract: The present invention provides a method of producing autoantigens, compositions comprising autoantigenic fragments and methods of using autoantigenic fragments in the treatment of a condition associated with an autoimmune response. Also provided are assays for the detection or assessment of an autoimmune response.
    Type: Application
    Filed: October 29, 2004
    Publication date: May 26, 2005
    Inventors: Antony Rosen, Donald Nicholson, Livia Casciola-Rosen, Felipe Andrade, Sophie Roy, Nancy Thornberry
  • Autoantigenic fragments, methods and assays
    Patent number: 6855515
    Abstract: The present invention provides a method of producing autoantigens, compositions comprising autoantigenic fragments and methods of using autoantigenic fragments in the treatment of a condition associated with an autoimmune response. Also provided are assays for the detection or assessment of an autoimmune response.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: February 15, 2005
    Assignees: Merck & Co., Inc., Johns Hopkins University
    Inventors: Anthony Rosen, Livia Casciola-Rosen, Donald W. Nicholson, Felipe A. Andrade, Sophie Roy, Nancy A. Thornberry
  • Anti-tumor agent assay using PKR
    Patent number: 5670330
    Abstract: A method of screening human tissue for the presence of neoplastic cells, by determining the activity of PKR, P58 of anti-P58 in test cells being screened, and identifying candidate neoplastic cells on the basis of subnormal PKR, P58, or anti-P58 activity. The activities may be determined directly by measuring protein kinase activity or its equivalent, or measured indirectly, by detecting functional mutations in the various proteins. Also disclosed are assay kits for carrying out the screening method.
    Type: Grant
    Filed: October 25, 1993
    Date of Patent: September 23, 1997
    Assignees: McGill University, University of Washington
    Inventors: Nahum Sonenberg, Michael G. Katze, Sophie Roy, Antonis E. Koromilas, Glen H. Barber