Abstract: A shoe care device includes an inner cabinet having an accommodation space configured to accommodate a shoe; a connection path configured to provide a flow path through which air from the accommodation space is introduced and then discharged back into the accommodation space; a nozzle duct having an upper discharge port that opens upward; a nozzle coupled to an end of the nozzle duct and having a lower discharge port that opens downward to spray air into the shoe; a blowing part; a dehumidifying part; a heating part; a regeneration path branching from the connection path to allow the air heated by the heating path to move therethrough; and a steam generator configured to supply steam to the inner cabinet. The steam supplied to the inner cabinet is sprayed to the shoe through the upper discharge port and the lower discharge port.

Abstract: A shoes care device includes an inner cabinet having an accommodation space; a connection path forming a flow path; a blower disposed in the connection path and configured to blow the air, a dehumidifier disposed in the connection path and configured to dehumidify the air, a heater disposed in the connection path and configured to heat the air, a regeneration path branched from the connection path and configured to move the air heated by the heating part therein; and a controller configured to perform control such that a drying stroke of drying the accommodation space and a regeneration stroke of regenerating the dehumidifying part before the drying stroke are selectively performed. The controller is configured to control air having passed through the dehumidifying part to be introduced into the accommodation space during a first regeneration stroke.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating skin diseases caused by radiation irradiation, comprising darapladib or a pharmaceutically acceptable salt thereof as an active ingredient, wherein darapladib improves damaged skin due to radiation irradiation, such as maintaining the water loss amount, water content level and pH level of damaged skin due to radiation irradiation, and recovering skin thickness and adipocyte area, and thus can be effectively used as a composition for preventing, treating or ameliorating skin diseases caused by radiation irradiation.

Abstract: A chimera protein according to the present application has a significantly increased in vivo half-life when administered because of a vWF domain coupled to FVIII, such that when used as a hemophilia A therapeutic agent, convenience for patients can be increased and medical expenses can be reduced.

Abstract: The present invention relates to a factor VIII or factor IX gene knockout rabbit, a method for preparing the same and a use thereof and, more particularly, to a transgenic rabbit whose factor VIII or factor IX gene has been knocked out through the CRISPR/Cas9 system, a method for preparing the same and a use thereof. According to the present invention, in the transgenic rabbit, whose factor VIII and/or factor IX gene has been knocked out, the functions of factor VIII and/or factor IX, which are proteins that perform critical functions for the development of hemophilia, are inhibited, such that the transgenic rabbit is useful for the development of hemophilia treatments.

Abstract: An electronic device is provided. The electronic device includes a processor configured to implement an execution screen area which is larger than a size of a display of the electronic device and comprises at least one object, and a display module configured to display, on a display of the electronic device, a display area which is at least a part of the implemented execution screen area. The processor determines a location of the at least one object based on a direction to which the electronic device faces and an attribute of the at least one object.

Abstract: A chimera protein according to the present application has a significantly increased in vivo half-life when administered because of a vWF domain coupled to FVIII, such that when used as a hemophilia A therapeutic agent, convenience for patients can be increased and medical expenses can be reduced.

Abstract: An electronic device and a display method thereof are provided. The electronic device includes a display; a rotary member configured to surround the display and to rotate around the display; and a control module configured to display a plurality of object groups on a plurality of layers of the display according to rotation of the rotary member.

Abstract: An electronic device and a display method thereof are provided. The electronic device includes a display; a rotary member configured to surround the display and to rotate around the display; and a control module configured to display a plurality of object groups on a plurality of layers of the display according to rotation of the rotary member.

Abstract: An electronic device is provided. The electronic device includes a processor configured to implement an execution screen area which is larger than a size of a display of the electronic device and comprises at least one object, and a display module configured to display, on a display of the electronic device, a display area which is at least a part of the implemented execution screen area. The processor determines a location of the at least one object based on a direction to which the electronic device faces and an attribute of the at least one object.

Abstract: An electronic device may include a communication interface for receiving a communication event and a processor that is configured to check a connected state or a mounted state of a body-mounted device and to differentially output at least one output interface related to the communication event corresponding to at least one of the connected state and the mounted state.

Abstract: Disclosed is the use of 2-oxoasiatic acid in the treatment of dementia or cognitive disorders.