Patents by Inventor Soren Bjorn

Soren Bjorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TF binding agent and use thereof
    Publication number: 20060018831
    Abstract: This invention relates to novel compounds, which bind to tissue factor and the use thereof for diagnostic and/or therapeutic purposes.
    Type: Application
    Filed: July 21, 2005
    Publication date: January 26, 2006
    Applicants: Novo Nordisk A/S, H:S RIGSHOSPITALET
    Inventors: Hesse Birger, Andreas Kjaer, Henning Stennicke, Soren Bjorn
  • Human spasmolytic polypeptide in glycosylated form
    Publication number: 20060019881
    Abstract: Human spasmolytic polypeptide (HSP) which has the amino acid sequence Glu Lys Pro Ser Pro Cys Gln Cys Ser Arg Leu Ser Pro His Asn Arg Thr Asn Cys Gly Phe Pro Gly Ile Thr Ser Asp Gln Cys Phe Asp Asn Gly Cys Cys Phe Asp Ser Ser Val Thr Gly Val Pro Trp Cys Phe His Pro Leu Pro Lys Gln Glu Ser Asp Gln Cys Val Met Glu Val Ser Asp Arg Arg Asn Cys Gly Tyr Pro Gly Ile Ser Pro Glu Glu Cys Ala Ser Arg Lys Cys Cys Phe Ser Asn Phe Ile Phe Glu Val Pro Trp Cys Phe Phe Pro Asn Ser Val Glu Asp Cys His Tyr or a functionally equivalent homologue thereof, characterized by being in glycosylated form.
    Type: Application
    Filed: July 19, 2005
    Publication date: January 26, 2006
    Inventors: Lars Thim, Kjeld Norris, Fanny Norris, Soren Bjorn, Mogens Christensen, Per Nielsen
  • Human spasmolytic polypeptide in glycosylated form
    Publication number: 20050287640
    Abstract: Human spasmolytic polypeptide (HSP) which has the amino acid sequence Glu Lys Pro Ser Pro Cys Gln Cys Ser Arg Leu Ser Pro His Asn Arg Thr Asn Cys Gly Phe Pro Gly Ile Thr Ser Asp Gln Cys Phe Asp Asn Gly Cys Cys Phe Asp Ser Ser Val Thr Gly Val Pro Trp Cys Phe His Pro Leu Pro Lys Gln Glu Ser Asp Gln Cys Val Met Glu Val Ser Asp Arg Arg Asn Cys Gly Tyr Pro Gly Ile Ser Pro Glu Glu Cys Ala Ser Arg Lys Cys Cys Phe Ser Asn Phe Ile Phe Glu Val Pro Trp Cys Phe Phe Pro Asn Ser Val Glu Asp Cys His Tyr or a functionally equivalent homologue thereof, characterized by being in glycosylated form.
    Type: Application
    Filed: May 27, 2005
    Publication date: December 29, 2005
    Inventors: Lars Thim, Kjeld Norris, Fanny Norris, Soren Bjorn, Mogens Christensen, Per Nielsen
  • Pegylated factor VII glycoforms
    Publication number: 20050113565
    Abstract: The invention concerns a preparation comprising a plurality of Factor VII polypeptides or Factor VII-related polypeptides, wherein the polypeptides comprise asparagine-linked and/or serine-linked oligosaccharide chains, and wherein at least one oligosaccharide group is covalently attached to at least one polymeric group.
    Type: Application
    Filed: June 30, 2003
    Publication date: May 26, 2005
    Inventors: Niels Klausen, Soren Bjorn, Carsten Behrens, Patrick Garibay
  • Pharmaceutical formulation
    Publication number: 20030162711
    Abstract: The invention relates to pharmaceutical formulations comprising growth hormone, an amino acid selected from the group of Asp, Ile, Val, Leu or His, or a derivative of histidine, or a peptide comprising at least one basic amino acid and at least one acidic amino acid, and a non-ionic detergent, eg. polysorbate or poloxamer.
    Type: Application
    Filed: January 22, 2003
    Publication date: August 28, 2003
    Inventors: Soren Bjorn, Hans Holmegaard Sorensen, Peter Langballe, Silke Moller Larsen, Kirsten Ebbehoj, Birthe Lykkegaard Hansen
  • Aprotinin variants having improved properties
    Publication number: 20030096752
    Abstract: The present invention relates to aprotinin variants having improved enzyme-inhibitory, immunological and pharmacokinetic properties and their preparation.
    Type: Application
    Filed: September 23, 2002
    Publication date: May 22, 2003
    Inventors: Werner Schroder, Soren Bjorn, Kjeld Norris, Viggo Diness, Leif Norkskov-Lauritsen, Niels Dyhr Christensen
  • Human spamolytic polypeptide in glycosylated form
    Publication number: 20030077696
    Abstract: A human spasmolytic polypeptide (HSP) having the amino acid SEQ ID NO:1, characterized by being in a glycosylated form.
    Type: Application
    Filed: March 20, 2000
    Publication date: April 24, 2003
    Inventors: Lars Thim, Kjeld Norris, Fanny Norris, Soren Bjorn, Mogens Christensen, Per Franklin Nielsen
  • Aprotinin variants having improved properties
    Patent number: 6482798
    Abstract: The present invention relates to aprotinin variants having improved enzyme-inhibitory, immunological and pharmacokinetic properties and their preparation.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: November 19, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Werner Schröder, Søren Bjørn, Kjeld Norris, Viggo Diness, Leif Nørkskov-Lauritsen, Niels Dyhr Christensen
  • Microparticle preparation
    Publication number: 20020102311
    Abstract: A parenterally administrable, biodegradable microparticle preparation containing a biologically active substance which, during the first 24 hours after injection, exhibits a release of the active substance that is less than 25% of the total release, determined from a concentration-time curve in the form of the ratio between the area under the curve during the said first 24 hours and the total area under the curve in question
    Type: Application
    Filed: January 10, 2002
    Publication date: August 1, 2002
    Inventors: Nils Ove Gustavsson, Monica Jonsson, Timo Laakso, Mats Reslow, Soren Bjorn, Jorn Drustrup
  • APROTININ VARIANTS HAVING IMPROVED PROPERTIES
    Publication number: 20020103334
    Abstract: The present invention relates to aprotinin variants having improved enzyme-inhibitory, immunological and pharmacokinetic properties and their preparation.
    Type: Application
    Filed: July 17, 1997
    Publication date: August 1, 2002
    Inventors: WERNER SCHRODER, SOREN BJORN, KJELD NORRIS, VIGGO DINESS, LEIF NORKSKOV-LAURITSEN, NIELS DYHR CHRISTENSEN
  • PHARMACEUTICAL FORMULATION
    Publication number: 20020077461
    Abstract: The invention relates to pharmaceutical formulations comprising growth hormone, an amino acid selected from the group of Asp, Ile, Val, Leu or His, or a derivative of histidine, or a peptide comprising at least one basic amino acid and at least one acidic amino acid, and a non-ionic detergent, eg. polysorbate or poloxamer.
    Type: Application
    Filed: April 23, 1997
    Publication date: June 20, 2002
    Inventors: SOREN BJORN, HANS HOLMEGAARD SORENSEN, PETER LANGBALLE, SILKE MOLLER LARSEN, KIRSTEN EBBEHOJ, BIRTHE LYKKEGAARD HANSEN
  • Yeast processing system
    Patent number: 5395922
    Abstract: A polypeptide for production in yeast comprises a fusion of a signal peptide, a leader peptide and a heterologous protein or polypeptide. The polypeptide is modified in its amino acid sequence adjacent to a yeast processing site positioned between the C-terminal end of the leader peptide and the N-terminal end of the heterologous protein so as to provide a presentation of the processing site which makes it accessible to proteolytic cleavage. Such a presentation is provided by adding one or more amino acids (at least one of which is negatively charged) to either the C-terminal end of the leader or the N-terminal end of the protein, or both. The heterologous protein may, for instance, be aprotinin or insulin precursor or an analogue thereof.
    Type: Grant
    Filed: February 15, 1994
    Date of Patent: March 7, 1995
    Assignee: Novo Nordisk A/S
    Inventors: Soren Bjorn, Kjeld Norris, Fanny Norris