Patents by Inventor Soren Flensted Lassen
Soren Flensted Lassen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120151633Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: ApplicationFiled: February 17, 2012Publication date: June 14, 2012Applicants: NOVOZYMES, INC., NOVOZYMES A/SInventors: Søren Flensted Lassen, Paul Harris, Elena Vlasenko, Kristian Bertel Romer Morkeberg Krogh
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Patent number: 8143482Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: GrantFiled: March 9, 2007Date of Patent: March 27, 2012Assignees: Novozymes, Inc., Novozymes AlsInventors: Søren Flensted Lassen, Paul Harris, Elena Vlasenko, Kristian Bertel Romer Morkeberg Krogh
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Patent number: 8119386Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: GrantFiled: January 26, 2011Date of Patent: February 21, 2012Assignee: Novozymes AlsInventors: Mads Norregaard-Madsen, Peter Rahbek Ostergaard, Claus Bo Voge Christensen, Soren Flensted Lassen
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Publication number: 20110135619Abstract: Isolated polypeptides are disclosed selected from the group consisting of: (a) polypeptides comprising an amino acid sequence which has at least 90% identity with a sequence of a mature polypeptide comprised in the group of SEQ ID NO: 26 to SEQ ID NO:50; (b) polypeptides which are encoded a nucleotide sequence which hybridize under high stringency conditions with a polynucleotide probe selected from the group consisting of (i) the complementary strand to a nucleotide sequence selected from the group of regions of SEQ ID NO: 1 to SEQ ID NO: 25 encoding a mature polypeptide.Type: ApplicationFiled: February 9, 2011Publication date: June 9, 2011Applicant: Novozymes A/SInventors: Reinhard Wilting, Soren Flensted Lassen, Peter Rahbek Ostergaard
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Publication number: 20110117624Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: ApplicationFiled: January 26, 2011Publication date: May 19, 2011Applicant: Novozymes A/SInventors: Mads Norregaard-Madsen, Peter Rabbek Østergaard, Claus Bo Voge Christensen, Søren Flensted Lassen
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Publication number: 20110097445Abstract: The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.Type: ApplicationFiled: January 5, 2011Publication date: April 28, 2011Applicant: Novozymes A/SInventors: Leonardo De Maria, Carsten Andersen, Lars Lehmann Hylling Christensen, Søren Flensted Lassen, Peter Rahbek Østergaard
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Patent number: 7910348Abstract: Disclosed are isolated polypeptides of Alicyclobacillus sp. having glutamic peptidase activity.Type: GrantFiled: August 4, 2008Date of Patent: March 22, 2011Assignee: Novozymes A/SInventors: Reinhard Wilting, Soren Flensted Lassen, Peter Rahbek Ostergaard
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Patent number: 7901918Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: GrantFiled: January 9, 2009Date of Patent: March 8, 2011Assignee: Novozymes A/SInventors: Mads Norregaard-Madsen, Peter Rahbek Ostergaard, Claus Bo Voge Christensen, Soren Flensted Lassen
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Publication number: 20110047652Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: ApplicationFiled: March 9, 2007Publication date: February 24, 2011Applicants: Novozymes, Inc., Novozymes A/SInventors: Søren Flensted Lassen, Paul Harris, Elena Vlasenko, Kristian Bertel Romer Morkeberg Krogh
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Patent number: 7892808Abstract: The invention relates to a novel 3D structure determined for a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an altered temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention further relates to methods of generating and preparing protease variants having different properties.Type: GrantFiled: October 8, 2004Date of Patent: February 22, 2011Assignee: Norozymes A/SInventors: Leonardo De Maria, Carsten Andersen, Lars Lehmann Hylling Christensen, Soren Flensted Lassen, Peter Rahbek Ostergaard
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Publication number: 20100107342Abstract: The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity and comprises a first amino acid sequence having the following sequence (SEQ ID NO: 79) Thr Arg Xaa Xaa Asp Cys Cys Xaa Xaa Xaa Cys Xaa 1???2???3???4???5???6???7???8???9???10??11??12 Trp Xaa 13??14 and a second amino acid sequence having the following sequence Trp Cys Cys Xaa Cys (SEQ ID NO: 80) 1???2???3???4???5 wherein, at position 3 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 4 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 8 of the first sequence, the amino acid is Arg, Lys or His; at positions 9, 10, 12 and 14, respectively, of the first sequence, and at position 4 of the second sequence, the amino acid is any of the 20 naturally occurring amino acid residues with the provisos that, in the first amino acid sequence, (i) when the amino residue at position 12 is Ser, then the amino acid residType: ApplicationFiled: September 25, 2009Publication date: May 6, 2010Applicant: NOVOZYMES A/SInventors: MARTIN SCHULEIN, TORBEN HENRIKSEN, LENE NONBOE ANDERSEN, SOREN FLENSTED LASSEN, MARKUS SAKARI KAUPPINEN, LENE LANGE, RUBY IIUM NIELSEN, SHINOBU TAKAGI, MICHIKO IHARA
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Publication number: 20090148924Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: ApplicationFiled: January 9, 2009Publication date: June 11, 2009Applicant: Novozymes A/SInventors: Mads Norregaard-Madsen, Peter Rahbek Ostergaard, Claus Bo Voge Christensen, Soren Flensted Lassen
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Patent number: 7537922Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: GrantFiled: February 27, 2007Date of Patent: May 26, 2009Assignee: Novozymes A/SInventors: Mads Norregaard-Madsen, Peter Rahbek Østergaard, Claus Bo Voge Christensen, Søren Flensted Lassen
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Publication number: 20090092707Abstract: Isolated polypeptides are disclosed selected from the group consisting of: (a) polypeptides comprising an amino acid sequence which has at least 90% identity with a sequence of a mature polypeptide comprised in the group of SEQ ID NO: 26 to SEQ ID NO:50; (b) polypeptides which are encoded a nucleotide sequence which hybridize under high stringency conditions with a polynucleotide probe selected from the group consisting of (i) the complementary strand to a nucleotide sequence selected from the group of regions of SEQ ID NO: 1 to SEQ ID NO: 25 encoding a mature polypeptide.Type: ApplicationFiled: August 4, 2008Publication date: April 9, 2009Applicant: Novozymes A/SInventors: Reinhard Wilting, Soren Flensted Lassen, Peter Rahbek Ostergaard
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Publication number: 20090047387Abstract: The invention relates to a novel 3D structure encoding a Nocardiopsis protease, as well as to variants of parent protease homologous to Nocardiopsis proteases, preferably of improved thermostability and/or with an amended temperature activity profile. The invention also relates to DNA sequences encoding such variants, their production in a recombinant host cell, as well as methods of using the variants, in particular within the field of animal feed and detergents. The invention furthermore relates to methods of generating and preparing protease variants of amended properties.Type: ApplicationFiled: October 8, 2004Publication date: February 19, 2009Applicant: Novozymes A/SInventors: Leonardo De Maria, Carsten Andersen, Lars Lehmann Hylling Christensen, Soren Flensted Lassen, Peter Rahbek Ostergaard
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Patent number: 7485447Abstract: A secreted proteolytic polypeptide comprising at least three non-polar or uncharged polar amino acids within the last four amino acids of the C-terminus of the polypeptide, encoding polynucleotides, expression vectors comprising the polynucleotides, host cell comprising the polynucleotides, methods for producing said polypeptide, and methods for using the polypeptide.Type: GrantFiled: June 21, 2004Date of Patent: February 3, 2009Assignee: Novozymes A/SInventor: Soren Flensted Lassen
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Publication number: 20080293104Abstract: A secreted mature polypeptide derived from an S2A or S1E protease which after maturation has protease activity, which polypeptide when expressed and before maturation comprises a heterologous pro-region.Type: ApplicationFiled: June 27, 2008Publication date: November 27, 2008Applicant: Novozymes A/SInventor: Soren Flensted Lassen
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Publication number: 20080286415Abstract: Proteases derived from Nocardiopsis dassonvillei subsp. dassonvillei DSM 43235, Nocardiopsis prasina DSM 15649, Nocardiopsis prasina (previously alba) DSM 14010 Nocardiopsis sp. DSM 16424, Nocardiopsis alkaliphila DSM 44657 and Nocardiopsis lucentensis DSM 44048, as well as homologous proteases; their recombinant production in various hosts, including transgenic plants and non-human animals, and their use in animal feed and detergents. The proteases are acid-stable, alkali-stable, and/or thermostable.Type: ApplicationFiled: June 17, 2005Publication date: November 20, 2008Applicant: Novozymes A/SInventors: Soren Flensted Lassen, Carsten Sjoeholm, Peter Rahbek Oestergaard, Morten Fischer
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Publication number: 20080220118Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: November 19, 2007Publication date: September 11, 2008Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehman, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss
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Publication number: 20080219965Abstract: The present invention relates to phytase variants, their preparation and uses, which phytase variants, when aligned according to FIG. 1, are amended as compared to a model phytase in at least one of a number of positions. Preferred model phytases are basidiomycete and ascomycete phytases, such as Peniophora phytase and Aspergillus phytases. Preferred phytase variants exhibits amended activity characteristics, such as improved specific activity and/or improved thermostability.Type: ApplicationFiled: November 19, 2007Publication date: September 11, 2008Applicant: Novozymes A/SInventors: Allan Svendsen, Soren Flensted Lassen, Dirk Kostrewa, Luis Pasamontes, Martin Lehmann, Andrea Tomschy, Adolphus Van Loon, Kurt Vogel, Markus Wyss