Patents by Inventor Sorin Istrail

Sorin Istrail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060046256
    Abstract: The present teachings describe methods for selecting informative genetic markers including single nucleotide polymorphisms (SNPs) that may be used in the design and execution of genome wide association studies. These methods are distinguished from other methods relying on a predefined haplotype block structure and may be configured to make use of correlations that occur across neighboring haplotype blocks. The disclosed methods may further be implemented across chromosomal regions having both high and low local linkage disequilibrium. Informative genetic marker selection, as described, provides an alternative and potentially more efficient mechanism to select genetic markers such as SNPs using block-based and random approaches.
    Type: Application
    Filed: January 21, 2005
    Publication date: March 2, 2006
    Applicant: Applera Corporation
    Inventors: Bjarni Halldorsson, Vineet Bafna, Ross Lippert, Russell Schwartz, Francisco De La Vega, Andrew Clark, Sorin Istrail
  • Publication number: 20040072249
    Abstract: The present teachings are related to methods for predicting the binding affinity of peptides for proteins. Individual methods for creating predictions and methods for combining predictions are also related. Some embodiments of the present teachings include methods for manufacturing a vaccine and a computer system for implementing the methods of the present teachings.
    Type: Application
    Filed: June 27, 2003
    Publication date: April 15, 2004
    Inventors: Stephen L. Hoffman, Sorin Istrail, Liliana Florea, Bjarni V. Halldorsson, Oliver Kohlbacher, Russell S. Schwartz