Patents by Inventor Sorina MORAR-MITRICA

Sorina MORAR-MITRICA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low concentration antibody formulations
    Patent number: 10537638
    Abstract: The present invention is directed formulations for low concentrations of therapeutic proteins and methods of making the same. In one aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) a surfactant; wherein the molar ratio of surfactant to therapeutic protein is at least 100. In another aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) an antioxidant, wherein the molar ratio of antioxidant to therapeutic protein is at least 750.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 21, 2020
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
    Inventors: George Crotts, Sorina Morar-Mitrica
  • LOW CONCENTRATION ANTIBODY FORMULATIONS
    Publication number: 20160000916
    Abstract: The present invention is directed formulations for low concentrations of therapeutic proteins and methods of making the same. In one aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) a surfactant; wherein the molar ratio of surfactant to therapeutic protein is at least 100. In another aspect the present invention is directed to a formulation for a therapeutic protein comprising: a) the therapeutic protein; and b) an antioxidant, wherein the molar ratio of antioxidant to therapeutic protein is at least 750.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 7, 2016
    Inventors: George CROTTS, Sorina MORAR-MITRICA
  • TNF-ALPHA ANTIGEN-BINDING PROTEINS
    Publication number: 20150368333
    Abstract: The present invention provides antigen binding proteins which bind specifically to TNF-alpha. For example novel variants of anti-TNF antibodies such as adalimumab which show increased binding to the FcRn receptor or increased half life compared to adalimumab. Also provided are compositions comprising the antigen binding proteins and uses of such compositions in treatment of disorders and disease.
    Type: Application
    Filed: January 22, 2014
    Publication date: December 24, 2015
    Inventors: George H. CROTTS, Sorina MORAR-MITRICA