Patents by Inventor Soumi Gupta

Soumi Gupta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8637252
    Abstract: This invention relates, in part, to methods and compositions for determining altered susceptibility of a human immunodeficiency virus (“HIV”) to the non-nucleoside reverse transcriptase inhibitors (“NNRTIs”) efavirenz (“EFV”), nevirapine (“NVP”), and delavirdine (“DLV”), the nucleoside reverse transcriptase inhibitor AZT, and the integrase strand transfer inhibitors diketo acid 1, diketo acid 2, and L-870,810 by detecting the presence of a mutation or combinations of mutations in the gene encoding HIV reverse transcriptase that are associated with altered susceptibility to the anti-HIV drugs.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: January 28, 2014
    Assignee: Monogram Biosciences, Inc.
    Inventors: Soumi Gupta, Signe Fransen, Ellen Paxinos, Neil T. Parkin
  • Publication number: 20120135395
    Abstract: This invention relates, in part, to methods and compositions for determining altered susceptibility of a human immunodeficiency virus (“HIV”) to the non-nucleoside reverse transcriptase inhibitors (“NNRTIs”) efavirenz (“EFV”), nevirapine (“NVP”), and delavirdine (“DLV”), the nucleoside reverse transcriptase inhibitor AZT, and the integrase strand transfer inhibitors diketo acid 1, diketo acid 2, and L-870,810 by detecting the presence of a mutation or combinations of mutations in the gene encoding HIV reverse transcriptase that are associated with altered susceptibility to the anti-HIV drugs.
    Type: Application
    Filed: November 15, 2011
    Publication date: May 31, 2012
    Applicant: MONOGRAM BIOSCIENCES, INC.
    Inventors: SOUMI GUPTA, SIGNE FRANSEN, ELLEN PAXINOS, NEIL T. PARKIN
  • Publication number: 20120003667
    Abstract: Methods for measuring hetero- and homodimerization of HIV reverse transcriptase (HIV RT) are provided using pairs of tagged probes and cleaving probes. The methods can be used, for example, to screen for modulators of HIV RT dimerization. Also provided are methods of determining whether a compound modulates HIV RT. Further provided are methods of determining whether a compound modulates formation of a complex between a p66 and p51, p66 and p66, or p51 and p55 subunits polypeptides of HIV RT.
    Type: Application
    Filed: June 16, 2008
    Publication date: January 5, 2012
    Inventors: Soumi Gupta, Rajiv Dua, Douglas McCann
  • Patent number: 8071284
    Abstract: This invention relates, in part, to methods and compositions for determining altered susceptibility of a human immunodeficiency virus (“HIV”) to the non-nucleoside reverse transcriptase inhibitors (“NNRTIs”) efavirenz (“EFV”), nevirapine (“NVP”), and delavirdine (“DLV”), the nucleoside reverse transcriptase inhibitor AZT, and the integrase strand transfer inhibitors diketo acid 1, diketo acid 2, and L-870,810 by detecting the presence of a mutation or combinations of mutations in the gene encoding HIV reverse transcriptase that are associated with altered susceptibility to the anti-HIV drugs.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: December 6, 2011
    Assignee: Monogram Biosciences, Inc.
    Inventors: Soumi Gupta, Signe Fransen, Ellen Paxinos, Neil T. Parkin
  • Publication number: 20090136915
    Abstract: This invention relates, in part, to methods and compositions for determining altered susceptibility of a human immunodeficiency virus (“HIV”) to the non-nucleoside reverse transcriptase inhibitors (“NNRTIs”) efavirenz (“EFV”), nevirapine (“NVP”), and delavirdine (“DLV”), the nucleoside reverse transcriptase inhibitor AZT, and the integrase strand transfer inhibitors diketo acid 1, diketo acid 2, and L-870,810 by detecting the presence of a mutation or combinations of mutations in the gene encoding HIV reverse transcriptase that are associated with altered susceptibility to the anti-HIV drugs.
    Type: Application
    Filed: June 6, 2006
    Publication date: May 28, 2009
    Applicant: Monogram Biosciences, Inc.
    Inventors: Soumi Gupta, Signe Fransen, Ellen Paxinos, Neil T. Parkin