Patents by Inventor Soumitra Roy

Soumitra Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENOVIRAL GENE THERAPY VECTORS
    Publication number: 20240108752
    Abstract: The present disclosure includes adenoviral vectors characterized by efficient transduction of HSCs, e.g., for in vivo gene therapy. The present disclosure includes, among other things, Ad3, Ad7, Ad11, Ad14, Adpatentdocket@choate.com16, Ad21, Ad34, Ad37, and Ad50 vectors and genomes. Ad3, Ad7, Ad11, Ad14, Ad16, Ad21, Ad34, Ad37, and Ad50 vectors and genomes of the present disclosure can include therapeutic payloads.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 4, 2024
    Inventors: Soumitra Roy, Ashvin Reddy Bashyam
  • Adenovirus and uses thereof
    Patent number: 11872281
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: January 16, 2024
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • Simian adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50, and uses thereof
    Patent number: 11807866
    Abstract: A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 7, 2023
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Soumitra Roy, James M. Wilson, Luc H. Vandenberghe
  • Hepatitis B virus (HBV) vaccines and uses thereof
    Patent number: 11725194
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: August 15, 2023
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy
  • Adenovirus vectors and uses thereof
    Patent number: 11459583
    Abstract: Provided herein are chimeric adenoviral vectors. The provided chimeric adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 4, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Jort Vellinga, Selina Khan, Jerome H. Hv. Custers
  • Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines
    Patent number: 11389531
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: July 19, 2022
    Assignees: Janssen Sciences Ireland Unlimited Company, Ichor Medical Systems, Inc.
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox, Dorien De Pooter
  • Adenovirus and uses thereof
    Patent number: 11236361
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: February 1, 2022
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • Adenovirus and uses thereof
    Patent number: 11142551
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 12, 2021
    Assignee: Janssen Vaccines & Prevention B.V.
    Inventors: Taco Gilles Uil, Soumitra Roy, Selina Khan, Jerôme H. H. V. Custers
  • HEPATITIS B VIRUS (HBV) VACCINES AND USES THEREOF
    Publication number: 20210269778
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 2, 2021
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY
  • Methods and Compositions for Inducing an Immune Response Against Hepatitis B Virus (HBV)
    Publication number: 20210268104
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Application
    Filed: May 18, 2021
    Publication date: September 2, 2021
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY, Jerôme Hubertina Henricus Victor CUSTERS, Roland Christian ZAHN, Markus KALLA
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20210214398
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: July 15, 2021
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H, H, V, CUSTERS
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20210198690
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: July 1, 2021
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H, H, V, CUSTERS
  • Hepatitis B virus (HBV) vaccines and uses thereof
    Patent number: 11021692
    Abstract: Polynucleotides encoding hepatitis B virus (HBV) core antigen and polymerase antigen, and related combinations are described. Also described are vectors, such as DNA plasmids or viral vectors, expressing the HBV core and polymerase antigens, and immunogenic compositions containing the expression vectors. Methods of inducing an immune response against HBV or treating a HBV-induced disease, particularly in individuals having chronic HBV infection, using the immunogenic compositions are also described.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: June 1, 2021
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Dorien De Pooter
  • Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV)
    Patent number: 11020476
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: June 1, 2021
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Jerôme Hubertina Henricus Victor Custers, Roland Christian Zahn, Markus Kalla
  • ADENOVIRUS VECTORS AND USES THEREOF
    Publication number: 20200347405
    Abstract: Provided herein are chimeric adenoviral vectors. The provided chimeric adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: November 5, 2020
    Inventors: Taco Gilles UIL, Soumitra ROY, Jort VELLINGA, Selina KHAN, Jerome H.HV. Custers
  • ADENOVIRUS AND USES THEREOF
    Publication number: 20200323977
    Abstract: Provided herein are adenoviral nucleic acid sequences and adenoviral vectors comprising said nucleic acid sequences. The provided adenoviral vectors can be used to induce a protective immune response in a subject.
    Type: Application
    Filed: October 30, 2018
    Publication date: October 15, 2020
    Inventors: Taco Gilles UIL, Soumitra ROY, Selina KHAN, Jerôme H.H.V. CUSTERS
  • Simian Adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50, and Uses Thereof
    Publication number: 20200263201
    Abstract: A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
    Type: Application
    Filed: October 29, 2019
    Publication date: August 20, 2020
    Inventors: Soumitra Roy, James M. Wilson, Luc H. Vandenberghe
  • Simian adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50, and uses thereof
    Patent number: 10501757
    Abstract: A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: December 10, 2019
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Soumitra Roy, James M. Wilson, Luc H. Vandenberghe
  • METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE AGAINST HEPATITIS B VIRUS (HBV)
    Publication number: 20190184011
    Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel BODEN, Helen HORTON, Jean-Marc Edmond Fernand Marie NEEFS, Soumitra ROY, Jerôme Hubertina Henricus Victor CUSTERS, Roland Christian ZAHN, Markus KALLA
  • METHODS AND APPARATUS FOR THE DELIVERY OF HEPATITIS B VIRUS (HBV) VACCINES
    Publication number: 20190184010
    Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.
    Type: Application
    Filed: December 18, 2018
    Publication date: June 20, 2019
    Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox