Abstract: A method including generating, by a navigation service, a route for navigating from a route origin to a route destination using a private roads repository. The method includes identifying a ghost origin and a ghost destination of a ghost road along the route. The method includes sending, using an application programming interface of a base roads engine, a first request for a route from the ghost origin to the ghost destination. The method includes receiving, from the base roads engine in response to the first request, a replacement section from the ghost origin to the ghost destination. The method includes replacing, in the route, the ghost road with the replacement section to create an updated route including segments. The method includes generating an estimated travel time from the route origin to the route destination over the segments of the updated route. The method includes presenting the estimated travel time.

Abstract: The present disclosure relates to the generation and uses of an improved set of biomarkers that are aryl hydrocarbon receptor (AHR) target genes, designated as “AHR biomarkers.” The AHR biomarkers described herein allow one to efficiently determine AHR activation groups and sub-groups, in particular for an improved classification of tumors. As used herein, AHR activation groups are called “AHR activation signatures”. The AHR biomarkers comprise markers that are important in diagnosis and therapy, for example for selecting patients for treatment with AHR activation modulating interventions, and monitoring of therapy response.

Abstract: The present invention relates to a newly identified AHR-activating enzyme and uses thereof as marker in the diagnosis and therapy, for example for selecting patients for treatment with IL4I1-modulating interventions, and monitoring of therapy response.

Abstract: Provided is a system and method for implementing remote trust services for blockchain. In one example, the method may include one or more of retrieving block content from a portion of a blockchain via an application programming interface (API), in response to a triggering event being detected, calling an off-chain trust service to sign the retrieved block content, receiving accreditation results of the retrieved block content from the off-chain trust service, the accreditation results comprising an indication of whether the retrieved block content has been successfully signed, and writing the received accreditation results to a block within the blockchain.

Abstract: Provided is a system and method for implementing remote trust services for blockchain. In one example, the method may include one or more of retrieving block content from a portion of a blockchain via an application programming interface (API), in response to a triggering event being detected, calling an off-chain trust service to sign the retrieved block content, receiving accreditation results of the retrieved block content from the off-chain trust service, the accreditation results comprising an indication of whether the retrieved block content has been successfully signed, and writing the received accreditation results to a block within the blockchain.