Patents by Inventor Sourabh Shukla

Sourabh Shukla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeting cancer cells and tissue using filamentous plant virus particles
    Patent number: 11896676
    Abstract: A pepino mosaic virus (PepMV) carrier comprising a PepMV particle that has been modified to carry an imaging agent or anticancer agent is described. The PepMV carrier can be used in a method of targeting cancer cells and tissue by administering it to a subject. Cancer tissue targeted by the PepMV carrier can be imaged using an imaging agent, or treated using an anticancer agent.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: February 13, 2024
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • FLOW METER CALIBRATION
    Publication number: 20240044691
    Abstract: A method can include receiving flow rate estimates from a computational, virtual flow meter at a wellsite; receiving flow rate measurements from a physical flow meter at the wellsite; and calling for calibration of the physical flow meter based on the flow rate estimates and the flow rate measurements.
    Type: Application
    Filed: August 4, 2023
    Publication date: February 8, 2024
    Inventors: Sourabh Shukla, Garud Sridhar
  • CANCER IMMUNOTHERAPY
    Publication number: 20220145316
    Abstract: Provided herein is a chimeric Potato virus X (PVX) filament conjugated to a therapeutic agent, a fusogenic peptide or a nucleolin-specific peptide ligand. In one aspect, they additionally comprise encapsulating a nucleic acid. Also provided are methods for use of the compositions diagnostically and therapeutically.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 12, 2022
    Inventors: Nicole Steinmetz, Sourabh Shukla
  • ANTI-CANCER PLANT VIRUS PARTICLES LINKED TO HER2 ANTIGENS
    Publication number: 20210060147
    Abstract: An anti-cancer virus composition including an icosahedral-shaped plant virus or virus-like particle linked to a HER2 antigen is described. The anti-cancer virus composition can be used for methods of treating or decreasing the risk of developing a HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the anti-cancer virus composition.
    Type: Application
    Filed: September 30, 2020
    Publication date: March 4, 2021
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • TARGETING CANCER CELLS AND TISSUE USING FILAMENTOUS PLANT VIRUS PARTICLES
    Publication number: 20210038741
    Abstract: A pepino mosaic virus (PepMV) carrier comprising a PepMV particle that has been modified to carry an imaging agent or anticancer agent is described. The PepMV carrier can be used in a method of targeting cancer cells and tissue by administering it to a subject. Cancer tissue targeted by the PepMV carrier can be imaged using an imaging agent, or treated using an anticancer agent.
    Type: Application
    Filed: August 7, 2020
    Publication date: February 11, 2021
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • Vaccination using plant virus particles linked to HER2 antigens
    Patent number: 10660949
    Abstract: A vaccine composition including a plant virus particle linked to an HER2 antigen is described. The vaccine composition can be used for methods of treating or preventing an HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the vaccine composition.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: May 26, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • VACCINATION USING PLANT VIRUS PARTICLES LINKED TO HER2 ANTIGENS
    Publication number: 20190030148
    Abstract: A vaccine composition including a plant virus particle linked to an HER2 antigen is described. The vaccine composition can be used for methods of treating or preventing an HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the vaccine composition.
    Type: Application
    Filed: October 16, 2018
    Publication date: January 31, 2019
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • Vaccination using plant virus particles linked to HER2 antigens
    Patent number: 10098936
    Abstract: A vaccine composition including a plant virus particle linked to an HER2 antigen is described. The vaccine composition can be used for methods of treating or preventing an HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the vaccine composition.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: October 16, 2018
    Assignee: Case Western Reserve University
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • Formation tester interval pressure transient test and apparatus
    Patent number: 10036245
    Abstract: A methodology for IPTT (interval pressure transient testing) design which allows estimation of the reliability of the transient tests. A normally distributed random noise is superimposed on analytical pressure profile computed for a given formation, PVT, and gauge metrology. The IPTT success in a particular environment is estimated based on the theoretical pressure derivative and noise superimposed pressure derivative. This approach is repeated for a range of rock, fluid properties, and practical limits, for a successful IPTT.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: July 31, 2018
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Prasanna Kumar Tellapaneni, Richard Jackson, Sourabh Shukla, Harshad Dixit
  • VACCINATION USING PLANT VIRUS PARTICLES LINKED TO HER2 ANTIGENS
    Publication number: 20170021003
    Abstract: A vaccine composition including a plant virus particle linked to an HER2 antigen is described. The vaccine composition can be used for methods of treating or preventing an HER2-expressing cancer in a subject by administering to a subject in need thereof an effective amount of the vaccine composition.
    Type: Application
    Filed: April 2, 2015
    Publication date: January 26, 2017
    Inventors: Nicole F. Steinmetz, Sourabh Shukla
  • Formation Tester Interval Pressure Transient Test And Apparatus
    Publication number: 20140316707
    Abstract: A methodology for IPTT (interval pressure transient testing) design which allows estimation of the reliability of the transient tests. A normally distributed random noise is superimposed on analytical pressure profile computed for a given formation, PVT, and gauge metrology. The IPTT success in a particular environment is estimated based on the theoretical pressure derivative and noise superimposed pressure derivative. This approach is repeated for a range of rock, fluid properties, and practical limits, for a successful IPTT.
    Type: Application
    Filed: November 5, 2012
    Publication date: October 23, 2014
    Inventors: Prasanna Kumar Tellapaneni, Richard Jackson, Sourabh Shukla, Harshad Dixit