Abstract: The present disclosure relates to field of quantum cryptography that discloses method of optimizing performance of Quantum Key Distribution (QKD) protocol. Computing system (101) extracts one or more coincidence distribution sets generated from one or more timestamps detected during communication by one or more detector pairs associated with sender and receiver of communication. Further, computing system identifies one or more reference lines indicating signal value and noise value in each of one or more coincidence distribution sets. Thereafter, computing system determines time window in one or more coincidence distribution sets by iteratively adjusting one or more reference lines in incremental steps until at least one of, performance parameters, signal value and noise value within time window complies with predefined requirements. Finally, computing system optimizes performance of QKD protocol based on determined time window.

Abstract: The present disclosure relates to field of quantum cryptography that discloses method of optimizing performance of Quantum Key Distribution (QKD) protocol. Computing system (101) extracts one or more coincidence distribution sets generated from one or more timestamps detected during communication by one or more detector pairs associated with sender and receiver of communication. Further, computing system identifies one or more reference lines indicating signal value and noise value in each of one or more coincidence distribution sets. Thereafter, computing system determines time window in one or more coincidence distribution sets by iteratively adjusting one or more reference lines in incremental steps until at least one of, performance parameters, signal value and noise value within time window complies with predefined requirements. Finally, computing system optimizes performance of QKD protocol based on determined time window.

Abstract: The present invention relates to substituted benzophenones of structural Formula I employed as small molecule inhibitor for controlling obesity. The present invention further relates to screening of small molecule inhibitors against p300 which selectively targets histone butyrylation thereby specifically inhibiting adipogenesis further aiding to prevention of weight gain. The present invention reveals that histone butyrylation increases during adipogenesis. Hence, inhibition of histone butyrylation by a small molecule inhibitor would be a promising therapeutic strategy to control obesity. Significantly, besides inhibiting adipogenesis in cellular model, it also prevents weight gain in high fat diet based mouse model system, indicating the possible use of the scaffold for obesity control.

Abstract: Disclosed herein are methods to inhibit a metalloprotein and methods to treat diseases and crop infections with a compound of formula I: X-L-Y ??I or a salt thereof. Also disclosed are novel compounds of formula I or a salt thereof and compositions comprising a compound of formula I.

Abstract: The invention refers to a modular continuous flow device for automated chemical multistep synthesis under continuous flow conditions. The device comprises a plurality of different types of continuous flow modules and a valve assembly for connecting the continuous flow modules to each other in a parallel or radial manner. This arrangement allows conducting chemical reaction sequences by pre-synthesizing and intermediately storing or simultaneously synthesizing at least one intermediate product which is needed in the main synthetic reaction sequence in order to obtain the final product.

Abstract: Disclosed herein are reactions, methods, reagents and compositions that utilize a nonheme iron halogenase enzyme to prepare compounds.

Abstract: A device may receive, from a source system, data in a first format, data in a second format, or a combination of data in the first format and data in the second format. The device may identify a data format type, a hierarchy depth, levels, and objects at each of the levels for the data and may generate a template based on the data format type, the hierarchy depth, the levels, and the objects at each of the levels. The device may generate a query, for the data in the first format, based on the template and may execute the query, on the data in the first format, to generate query results associated with a target system. The device may process the query results, with the template, to generate output data in a third format associated with the target system and may perform actions based on the output data.

Abstract: The disclosure provides a method for document management in a network. The method includes acquiring, by an electronic device, a source document as an image, extracting, by the electronic device, a plurality of multi-modal information from the source document by parsing the source document, automatically determining, by the electronic device, a category of the source document based on a comparison of the extracted plurality of multi-modal information with a plurality of pre-defined features, extracting, by the electronic device, a plurality of data fields corresponding to the determined category from the source document, determining, by the electronic device, a priority for each of the plurality of data fields and storing, by the electronic device, the plurality of data fields in at least one of a secure information source and an unsecure information source based on the determined priority.

Abstract: The invention refers to a modular continuous flow device for automated chemical multistep synthesis under continuous flow conditions. The device comprises a plurality of different types of continuous flow modules and a valve assembly for connecting the continuous flow modules to each other in a parallel or radial manner. This arrangement allows conducting chemical reaction sequences by pre-synthesizing and intermediately storing or simultaneously synthesizing at least one intermediate product which is needed in the main synthetic reaction sequence in order to obtain the final product.

Abstract: A system and method for optimizing solution identification for a problem is provided. The invention comprises generating multiple solutions for the problem by selecting population of datasets from a search space. Further, fitness of each generated solution is determined by utilizing a fitness approximation model for selecting solutions from the generated solutions for generating a next generation of solutions until the solutions converge based on a pre-determined convergence target. Further, solutions from the converged solutions are filtered by utilizing a filtering model for performing a concrete evaluation. The concrete evaluation is performed for identifying productive solutions and unproductive solutions from the solutions filtered from the converged solutions. Further, a feedback based on the concrete evaluation is provided. Furthermore, the solution identification for a problem is carried out iteratively until a termination condition is met.

Abstract: Disclosed are 3-indolyl furanoid compounds which are useful as potent anti-inflammatory agents and prevent gastric ulcer by inhibiting matrix metalloproteinase-9 (MMP-9) expression in gastric mucosal layer. For example, disclosed is a compound of formula 1, wherein: R1 to R6 is selected from H, OH, CH3, OCH3, Br, Cl, Ph or o-OHC6H4, OCH2—CH?CH2, or OCH2CH2CH3, and R1 to R6 is having at least one substituent with alkyl, aryl and heteroaryl groups other than H, wherein the carbon in alkyl, aryl and heteroaryl is in the range of C1 to C8. Various embodiments relate to representative compounds of Formula 1 and method of preparation thereof. Further embodiments relates to the use of representative compounds of Formula 1 in treating diseases associated with gastric ulcer and other inflammatory diseases. A noted feature of an embodiment is the IC50 value of 50 ?M of one of the 3-indolyl furanoids.

Abstract: A method and a device for providing contextual information. The method includes detecting an invocation of a camera application via a user-input while executing a non-camera application by a device. The method further includes identifying content from one or more of a preview of the camera application and multi-media captured by the camera application. Further, the method includes identifying contextual information based on one or more of the identified content and information available from the non-camera application. Further, the method includes allowing the identified contextual information to be shared between the camera application and the non-camera application.

Abstract: Disclosed are 3-indolyl furanoid compounds which are useful as potent anti-inflammatory agents and prevent gastric ulcer by inhibiting matrix metalloproteinase-9 (MMP-9) expression in gastric mucosal layer. For example, disclosed is a compound of formula 1, wherein: R1 to R6 is selected from H, OH, CH3, OCH3, Br, Cl, Ph or o-OHC6H4, OCH2—CH?CH2, or OCH2CH2CH3, and R1 to R6 is having at least one substituent with alkyl, aryl and heteroaryl groups other than H, wherein the carbon in alkyl, aryl and heteroaryl is in the range of C1 to C8. Various embodiments relate to representative compounds of Formula 1 and method of preparation thereof. Further embodiments relates to the use of representative compounds of Formula 1 in treating diseases associated with gastric ulcer and other inflammatory diseases. A noted feature of an embodiment is the IC50 value of 50 ?M of one of the 3-indolyl furanoids.