Abstract: A system and method for analyzing a data store of de-identified patient data to generate one or more dynamic user interfaces usable to predict an expected response of a particular patient population or cohort when provided with a certain treatment. The automated analysis of patterns occurring in patient clinical, molecular, phenotypic, and response data, as facilitated by the various user interfaces, provides an efficient, intuitive way for clinicians to evaluate large data sets to aid in the potential discovery of insights of therapeutic significance.

Abstract: A system for non-invasively creating a surgical lesion in subcutaneous tissue including an ultrasound generator, an ultrasound transducer operably connected to the ultrasound generator; an ultrasound enhancing target including at least two ultrasound reflecting filaments held in a spaced-apart relationship; said ultrasound generator supplying ultrasound at a pressure and frequency which will heat subcutaneous tissue and create a surgical lesion proximate the ultrasound enhancing target and will not create thermally mediated necrosis in the absence of the ultrasound enhancing target.