Patents by Inventor Sowmya Pattabhi

Sowmya Pattabhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HOMOLOGY DIRECTED REPAIR COMPOSITIONS FOR THE TREATMENT OF HEMOGLOBINOPATHIES
    Publication number: 20240124896
    Abstract: The present disclosure provides improved compositions for the homology directed repair of the human globin locus for the prevention, treatment, or amelioration of at least one symptom of a hemoglobinopathy.
    Type: Application
    Filed: June 29, 2023
    Publication date: April 18, 2024
    Applicants: Seattle Children's Hospital (d/b/a Seattle Children's Research Institute), Fred Hutchinson Cancer Center
    Inventors: Andrew Scharenberg, Kyle Jacoby, Hans-Peter Kiem, David J. Rawlings, Christopher Lux, Sowmya Pattabhi, Olivier M. Humbert
  • HOMOLOGY-DIRECTED REPAIR TEMPLATE DESIGN AND DELIVERY TO EDIT HEMOGLOBIN-RELATED MUTATIONS
    Publication number: 20210309995
    Abstract: Some embodiments of the methods and compositions provided herein relate to modifying hemoglobin loci, such as hemoglobin-related mutations including sickle cell mutations. Some embodiments relate to modification of a sickle cell mutation through introduction of a phosphodiester DNA strand break at the site of the sickle cell mutation.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 7, 2021
    Inventors: David J. Rawlings, Sowmya Pattabhi, Andrew M. Scharenberg, Kyle Jacoby
  • HOMOLOGY DIRECTED REPAIR COMPOSITIONS FOR THE TREATMENT OF HEMOGLOBINOPATHIES
    Publication number: 20210222201
    Abstract: The present disclosure provides improved compositions for the homology directed repair of the human globin locus for the prevention, treatment, or amelioration of at least one symptom of a hemoglobinopathy.
    Type: Application
    Filed: April 24, 2018
    Publication date: July 22, 2021
    Inventors: Andrew Scharenberg, Kyle Jacoby, Hans-Peter Kiem, David J. Rawlings, Christopher Lux, Sowmya Pattabhi, Olivier M. Humbert
  • T24 antigen for immunodiagnosis of cysticercosis
    Patent number: 7972606
    Abstract: The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences disclosed herein can be formulated into a pharmaceutical composition for administration to a subject. For example, the disclosed T24 polypeptides can also be administered to a subject to stimulate an immune response in the subject, thereby protecting the subject against T. solium infection.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: July 5, 2011
    Assignee: The United States of America as respresented by the Department of Health and Human Services
    Inventors: Kathy Hancock, Fatima Williams Whitfield, Melinda L. Yushak, Sowmya Pattabhi, Victor C.W. Tsang
  • T24 ANTIGEN FOR IMMUNODIAGNOSIS OF TAENIA SOLIUM CYSTICERCOSIS
    Publication number: 20090209470
    Abstract: The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences disclosed herein can be formulated into a pharmaceutical composition for administration to a subject. For example, the disclosed T24 polypeptides can also be administered to a subject to stimulate an immune response in the subject, thereby protecting the subject against T. solium infection.
    Type: Application
    Filed: April 29, 2009
    Publication date: August 20, 2009
    Inventors: Kathy Hancock, Fatima Williams Whitfield, Melinda L. Yushak, Sowmya Pattabhi, Victor C.W. Tsang
  • T24 antigen for immunodiagnosis of cysticercosis
    Patent number: 7547762
    Abstract: The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences disclosed herein can be formulated into a pharmaceutical composition for administration to a subject. For example, the disclosed T24 polypeptides can also be administered to a subject to stimulate an immune response in the subject, thereby protecting the subject against T. solium infection.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: June 16, 2009
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Kathy Hancock, Fatima Williams Whitfield, Melinda L. Yushak, Sowmya Pattabhi, Victor C. W. Tsang
  • T24 antigen for immunodiagnosis of taenia solium cysticercosis
    Publication number: 20060264614
    Abstract: The present disclosure relates to T24 nucleic acid sequences, amino acid sequences, and antibodies. Methods for detecting and diagnosing Taenia solium infection in a subject using the T24 sequences and specific binding agents are also disclosed. The T24 sequences disclosed herein can be formulated into a pharmaceutical composition for administration to a subject. For example, the disclosed T24 polypeptides can also be administered to a subject to stimulate an immune response in the subject, thereby protecting the subject against T. solium infection.
    Type: Application
    Filed: May 13, 2004
    Publication date: November 23, 2006
    Inventors: Kathy Hancock, Fatima Whitfield, Melinda Yushak, Sowmya Pattabhi, Victor Tsang