Patents by Inventor Spencer D. Dreher

Spencer D. Dreher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making N-sulfonated-amino acid derivatives
    Patent number: 7579487
    Abstract: This invention relates to a process for preparing optically active ?-amino acid substrates which are used to make potent lethal factor (LF) inhibitors for the treatment of anthrax. This invention further relates to a process for synthesis of potent LF-inhibitors for the treatment of anthrax. Specifically, the invention concerns a novel, high-yielding and highly enantioselective asymmetric hydrogenation reaction of a tetrasubstituted ene-sulfonamide acid or ester.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: August 25, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Spencer D. Dreher, Norihiro Ikemoto, C. Scott Shultz, J. Michael Williams
  • Process for the synthesis of trifluorophenylacetic acids
    Patent number: 6870067
    Abstract: The present invention is concerned with a process for the preparation of trifluorophenylacetic acids using a Grignard reagent and an allylating agent, such as allyl bromide.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: March 22, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Norihiro Ikemoto, Spencer D. Dreher
  • Process for the synthesis of trifluorophenylacetic acids
    Publication number: 20040077901
    Abstract: The present invention is concerned with a process for the preparation of trifluorophenylacetic acids using a Grignard reagent and an allylating agent, such as allyl bromide.
    Type: Application
    Filed: October 7, 2003
    Publication date: April 22, 2004
    Inventors: Norihiro Ikemoto, Spencer D. Dreher
  • Process for the synthesis of trifluorophenylacetic acids
    Publication number: 20040068141
    Abstract: The present invention addresses a process for the preparation of 2,4,5-trifluorophenylacetic acid using a Cu(I) salt as a catalyst.
    Type: Application
    Filed: October 7, 2003
    Publication date: April 8, 2004
    Inventors: Joseph D. Armstrong, Spencer D. Dreher, Norihiro Ikemoto