Patents by Inventor Spencer Knapp

Spencer Knapp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING MALARIA
    Publication number: 20230139910
    Abstract: Disclosed are methods of treating malaria with tetrahydrobenzonaphtyridine carboxanilide (TBN) derivatives and related pyrrolinones and hydrolysis products thereof. These compounds are active against Plasmodium falciparum strains that are resistant to multiple drugs currently on the market. The present invention further relates to novel compounds and pharmaceutical compositions comprising such compounds.
    Type: Application
    Filed: February 16, 2021
    Publication date: May 4, 2023
    Inventors: Spencer Knapp, Robert D. Barrows, R. Kiplin Guy, Jared Hammill, Christopher Davis
  • Abuse deterrent opioid agonist transdermal compositions and methods for their use
    Patent number: 9895384
    Abstract: The present disclosure is directed to abuse-resistant transdermal delivery compositions comprising opioid agonists.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: February 20, 2018
    Assignee: InteguRx Therapeutics, LLC
    Inventors: Agis Kydonieus, Spencer Knapp
  • Substituted 2-alkyl-1-OXO-N-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides for antimalarial therapies
    Patent number: 9416124
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl -1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: August 16, 2016
    Assignees: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, MMV MEDICINES FOR MALARIA VENTURE, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro
  • METHOD AND SYSTEM FOR NAVIGATING THROUGH A DATACENTER HIERARCHY IN A MOBILE COMPUTER DEVICE
    Publication number: 20160179798
    Abstract: A graphical user interface system is provided. The system includes a display configured to provide a plurality of panels, each panel associated with a document in a datacenter, wherein the datacenter comprises an architecture having a plurality of hierarchy layers, each hierarchy layer storing at least a document; a memory storing commands; and a processor coupled to the display and configured to execute the commands to cause the graphical user interface to navigate through the datacenter architecture by: receiving a first user gesture to access a first hierarchy layer in the datacenter; receiving a second user gesture to access a second hierarchy layer in the datacenter; and displaying in the display a visual effect when at least one of the first hierarchy layer and the second hierarchy layers are accessed. An apparatus including a graphical user interface system as above and a method for its use are also provided.
    Type: Application
    Filed: December 19, 2014
    Publication date: June 23, 2016
    Inventors: Matthew Peter Franks, Patrick Fabian Marsh, JR., Charles Martin Fisher, Philip Spencer Knapp, Justin Edward Boyce, Lauren Briana Mazzio, Eric Alan Boggs, Jonathan Kolko
  • SUBSTITUTED 2-ALKYL-1-OXO-N-PHENYL-3-HETEROARYL-1,2,3,4-TETRAHYDROISOQUINOLINE-4-CARBOXAMIDES FOR ANTIMALARIAL THERAPIES
    Publication number: 20140235593
    Abstract: In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl-1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 24, 2012
    Publication date: August 21, 2014
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Rodney Kiplin Guy, Fangyi Zhu, Wendyam Armand Guiguemde, David Floyd, Spencer Knapp, Philip Stein, Steve Castro