Abstract: The invention provides arylthioether acetamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as bacterial infections, and in inhibiting LpxA activity.

Abstract: A method may include pressing a mat including a blend of paper and plastic fragments by applying a pressure to the mat using a heated press such that the mat is compressed to a first thickness, where the pressure is greater than a critical pressure threshold such that at least a portion of a moisture content of the mat is in a super-heated liquid state. The method may include maintaining the pressure on the mat above the critical pressure threshold until at least a portion of the plastic fragments of the mat are melted. The method may include decreasing the pressure on the mat below the critical pressure threshold such that the mat expands to a second thickness greater than or equal to a target thickness, and such that the portion of the moisture content of the mat in the super-heated liquid state is converted to steam.

Abstract: Computer-implemented method for providing corrected plant-related index data, comprising the steps of: providing initial plant-related index data for an agricultural field, preferably based on at least one satellite image; and correcting the initial plant-related index data for the agricultural field at least based on historical plant-related index data for the agricultural field and providing corrected plant-related index data.

Abstract: A gastroenterologic sleeve is anchored within the digestive tract, without tissue-puncturing mechanisms, by providing anchoring mechanisms that utilize the inherent shape of the stomach to prevent sleeve migration. In at least two embodiments, the anchoring mechanism expands to conform to the interior stomach walls. In other embodiments, internal pessary rings are held in place at the gastroesophageal junction by an external band. A delivery device is provided for implanting the various device transesophageally.

Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.

Abstract: A method for generating a crop phenology prediction (7) is provided. The method comprises the steps of providing crop phenology training data (1) for a plurality of crops and a plurality of locations (17); training a machine learning system (6) using the crop phenology training data (1); providing a selection of the plurality of crops and a specific location (18); and generating a crop phenology prediction (7) for a selection of the plurality of crops at a specific location (18) using the trained machine learning system (6). Further, a system (21) for generating a crop phenology prediction (7) is provided.

Abstract: A system for predicting a resting position of a golf ball may use ball tracking sensor data to identify an impact location of the ball. Modeling of ball movement following impact may be performed that incorporates measured ball impact physics, impact coordinates, and material properties of ground or objects to which the impact coordinates correspond and, together with historical shot data corresponding to the impact coordinates or an encompassing zone, bounce and roll behavior and/or final resting position predictions may be generated.

Abstract: The present disclosure is generally directed to Siglec-9 ECDs and Siglec-9 ECD fusion molecules, and methods of treatment using Siglec-9 ECDs and Siglec-9 ECD fusion molecules.

Abstract: The present embodiments relate to a secure boot partition for a cloud computing device of a cloud computing system. The computing device of the cloud computing system can transmit a first request for a pre-boot execution environment executable from a smart network interface card (SmartNIC). The computing device can receive the pre-boot environment executable from the SmartNIC and verify the pre-boot execution environment executable. The computing device can execute the pre-boot execution environment executable. Executing the pre-boot execution environment executable can include transmitting a second request secure boot metadata from the SmartNIC and receiving the secure boot metadata. Executing the pre-boot execution environment executable can further include mounting a boot partition, loading a boot loader obtained from the boot partition, verifying the boot loader based at least in part on the secure boot metadata, and executing the boot loader in response to verifying the boot loader.

Abstract: A method includes: receiving, by a processor set, user input defining parameters of a project; receiving, by the processor set, opt-in input from team members defined in the parameters of the project; retrieving, by the processor set and from electronic data sources, data that corresponds to performance of tasks of the project by each of the team members; generating, by the processor set and based on the retrieved data, a respective contribution score of each of the team members; generating, by the processor set and based on the respective contribution scores of each of the team members, a respective allocation score of each of the team members; allocating, by the processor set, an award to the team members based on the respective allocation scores of each of the team members.

Abstract: A method of medical treatment for transecting a ring trapped on an appendage of a patient is described. The method of medical treatment includes inserting a safety guard between the appendage and a portion of the ring, activating a blade motor to rotate a rotary blade aligned with the safety guard, sensing status readings, and transecting the portion of the ring including automatically directing a safety guard actuator to move the safety guard, based at least in part on the status readings, toward the rotary blade thereby urging the ring into contact with the rotary blade.

Abstract: An apparatus to facilitate increasing processing resources in processing cores of a graphics environment is disclosed. The apparatus includes a plurality of processing resources to execute one or more execution threads; a plurality of message arbiter-processing resource (MA-PR) routers, wherein a respective MA-PR router of the plurality of MA-PR routers corresponds to a pair of processing resources of the plurality of processing resources and is to arbitrate routing of a thread control message from a message arbiter between the pair of processing resources; a plurality of local shared cache (LSC) sequencers to provide an interface between at least one LSC of the processing core and the plurality of processing resources; and a plurality of instruction caches (ICs) to store instructions of the one or more execution threads, wherein a respective IC of the plurality of ICs interfaces with a portion of the plurality of processing resources.

Abstract: The present disclosure provides a method of modifying a mutant dystrophin gene in the genome of a cell. The present disclosure further provides compositions and kits for modifying a mutant dystrophin gene in the genome of a cell.

Abstract: A flow cytometer of a blood analyzer including a transverse-electric (TE) laser diode, a flow cell, a quarter wave plate (QWP), a plurality of lenses, and a side scatter detector. The TE laser diode is configured to output a laser beam along an optical axis and has a fast axis full width at half maximum (FWHM) divergence of from about 16 degrees to about 25 degrees. The QWP is disposed along the optical axis between the TE laser diode and the flow cell and configured to circularly polarize the laser beam. The plurality of lenses is disposed between the TE laser diode and the flow cell and configured to focus the laser beam at the flow cell.

Abstract: The invention relates to a medical implant (1) comprising a patch (2). The implant is adapted to close a defect (3), preferably a an opening in a ventricular or atrial septum (4). The medical implant (1) comprises at least one mechanical anchor (5). The anchor may comprise a barb (6) and is adapted to pierce the patch (2) and/or biological tissue (4) such as to fix the medical implant (1) to said tissue (4). The medical implant can be deployed by a delivery device (7). The delivery device (7) may comprise a balloon (8?, 8?), preferably at least two balloons (8?, 8?).

Abstract: A method of impedance flow cytometry comprises: flowing a fluid along a flow channel; applying electrical signals to current paths through the fluid, the current paths comprising at least first and second current paths, and further first and second current paths, wherein the electrical signals applied to the first and further first current paths have a frequency, magnitude and phase, and the electrical signals applied to the second and further second current paths have substantially equal frequency and magnitude and opposite phase to the electrical signals applied to the first and first further current path; detecting current flow in the current paths; producing a first summed signal representing the sum of the current flows detected in the current paths, and a second summed signal representing the sum of the current flows detected in the further current paths; and obtaining a differential signal representing the difference between the summed signals.

Abstract: A method, computer system, and a computer program product is indicated to provide a solution to a user problem. In one embodiment, this comprises receiving a request from a user for a resolution to a user problem and obtaining a solution to a problem like the user problem from a knowledge-based repository and identifying a source associated with the similar problem. Other solutions are obtained from additional sources like the user problem. A final solution is provided to the user problem by incorporating information from the solutions from the repository and other sources. Information is incorporated to provide a complete resolution to the user problem through the final solutions. A search for any related updates is provided to determines when a similar update needs to be incorporated into the final solution in a future date based on information from the related updates.

Abstract: An osteotomy gap filling implants and related methods. In one example, the implant may include several implant segments, at least some of which include a porous body, in combination with a non-porous flexible spine extending through the implant segments.

Abstract: The present invention relates to the use of certain ?-lactamase inhibitors in conjunction with one or more ?-lactam antibiotics for the treatment of Strenotrophomonas maltophilia, tuberculosis or Pseudomonas species infections.