Patents by Inventor Spyros Stylianou

Spyros Stylianou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of determining cancer cell responsiveness to a notch inhibitory agent
    Patent number: 8748112
    Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: June 10, 2014
    Assignee: Trojan Technologies, Ltd.
    Inventor: Spyros Stylianou
  • Methods of Treating Cancer Using Notch Pathway Inhibitors
    Publication number: 20130022966
    Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
    Type: Application
    Filed: February 17, 2012
    Publication date: January 24, 2013
    Inventor: Spyros Stylianou
  • Antennapedia-dominant negative mastermind-like construct
    Patent number: 8119366
    Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: February 21, 2012
    Assignee: Trojan Technologies, Ltd.
    Inventor: Spyros Stylianou
  • METHODS OF TREATING CANCER USING NOTCH PATHWAY INHIBITORS
    Publication number: 20090137470
    Abstract: The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
    Type: Application
    Filed: October 3, 2008
    Publication date: May 28, 2009
    Inventor: Spyros Stylianou