Abstract: This disclosure relates generally to methods and systems for building an intelligent analytical platform to enable a device fabrication in material science. Material engineers and design engineers may face various challenges with existing knowledge, as more time and efforts are required in finding a relevant knowledge from the existing knowledge, mainly due to the unstructured form, for fabricating new devices. The present disclosure solves the technical problem of finding the relevant knowledge out of the existing knowledge, in a structured form by building an analytical platform. The unstructured format of the existing knowledge of the fabrication process is transformed into a structured format in terms of operation sequence knowledge graphs, using a set of artificial intelligence (AI) and machine learning models, and a knowledge representation model of the fabrication process. The structured format of the existing knowledge is hierarchically arranged to build the analytical platform.

Abstract: An air sanitizer unit that includes a housing, a substrate, and a light source. The substrate is provided in an interior space of the housing and includes at least one photocatalytic coating on at least one surface that extends along a flow path of airflow through the air sanitizer unit. The light source is disposed within the interior space of the housing in a way such that light produced by the light source activates the at least one photocatalytic coating to purify the airflow. Further, the substrate includes channels for allowing airflow there through, in which a substrate structure defining the channels include the photocatalytic coating and the substrate structure defining the channels is configured such that microbes in the airflow are captured on the least one photocatalytic coating at low airflow rates, in which the low airflow rates are airflow rates less than 20 air changes per hour.

Abstract: This disclosure relates generally to methods and systems for building an intelligent analytical platform to enable a device fabrication in material science. Material engineers and design engineers may face various challenges with existing knowledge, as more time and efforts are required in finding a relevant knowledge from the existing knowledge, mainly due to the unstructured form, for fabricating new devices. The present disclosure solves the technical problem of finding the relevant knowledge out of the existing knowledge, in a structured form by building an analytical platform. The unstructured format of the existing knowledge of the fabrication process is transformed into a structured format in terms of operation sequence knowledge graphs, using a set of artificial intelligence (AI) and machine learning models, and a knowledge representation model of the fabrication process. The structured format of the existing knowledge is hierarchically arranged to build the analytical platform.

Abstract: The present invention provides a process for the preparation of Docosanol (I). The process comprises reducing cis-13-Docosenoic acid (V) to obtain Docosanoic acid (III), which is further reduced to obtain Docosanol (I).

Abstract: The present invention relates to a process for the preparation of Tipiracil hydrochloride crystal III, which comprises reaction of Tipiracil with hydrochloric acid in presence of solvent is selected from alcohol and/or water. Further, the present invention relates to pure Tipiracil base having purity greater than about 99.0% by HPLC.

Abstract: A fluid distributing device that can be utilized in a refrigerated transport unit, an air duct for an HVAC system in a building, a heat exchanger, etc. The fluid distributing device includes a body having an outlet that directs fluid from the fluid distributing device and a positive fluid displacement device configured to draw fluid into an interior of the body. A method for a fluid distributing device to distribute air within an interior space of the refrigerated transport unit includes drawing air into the fluid distributing device and discharging air out of the fluid distributing device via an outlet.

Abstract: The present invention provides a process for the preparation of Docosanol (I). The process comprises reducing cis-13-Docosenoic acid (V) to obtain Docosanoic acid (III), which is further reduced to obtain Docosanol (I).

Abstract: The invention provides conjugate-based antifungal or antibacterial prodrugs formed by coupling at least one antifungal agent or antibacterial agent with at least one linker and/or carrier. The prodrugs are of formula: (i) (AFA)m-X-(L)n; (ii) [(AFA)m?-X]p-L; (iii) AFA-[X-(L)n?]q; or (iv) (AFA)m?-X, wherein: AFA is an antifungal agent or an antibacterial agent; L is a carrier; X is a linker; m ranges from 1 to 10; n ranges from 2 to 10; m? is 1 to 10; p is 1 to 10; n? is 1 to 10; and q is 1 to 10, provided that q? and n are not both 1; and m? is 1 to 10. The invention also provides nonaparticles comprising the conjugate-based prodrugs. Additionally, the invention also provides non-conjugated antifungal and antibacterial agents in the form of nanoparticles.

Abstract: The invention provides conjugate-based antifungal or antibacterial prodrugs formed by coupling at least one anti-fungal agent or antibacterial agent with at least one linker and/or carrier. The prodrugs are of formula: (i) (AFA)m-X-(L)n; (ii) [(AFA)m?-X]p-L; (iii) AFA-[X-(L)n?]q; or (iv) (AFA)m?-X, wherein: AFA is an antifungal agent or an antibacterial agent; L is a carrier; X is a linker; m ranges from 1 to 10; n ranges from 2 to 10; m? is 1 to 10; p is 1 to 10; n? is 1 to 10; and q is 1 to 10, provided that q? and n are not both 1; and m? is 1 to 10. The invention also provides nanoparticles comprising the conjugate-based prodrugs. Additionally, the invention also provides non-conjugated antifungal and antibacterial agents in the form of nanoparticles.

Abstract: A server. The server comprises a processor, a memory, and an application that receives an alert message corresponding to an error and a performance metric value in a messaging server, wherein the messaging server is one of a plurality of servers in a rotation that supports a front-end application in a system, identifies a course of action for repair, determines that the number of active servers in the rotation is above a predefined threshold number of active servers, removes the messaging server from the rotation, notifies a system administrator of the removal, the identified error, and the performance metric value, repairs the messaging server by implementing the identified course of action, validates the messaging server by running application programming interface (API) calls, places the repaired messaging server in the rotation, and notifies the system administrator of repair details and API call results.

Abstract: Systems, apparatus, and computer program products provide for a comprehensive quality assurance platform for automatically assessing the quality of work performance of associates. The described quality assurance system/module that can be implemented in conjunction with the work allocation system described herein or the system can operate as a standalone quality assurance system/module. The quality assurance system provides for automated collection and tracking of quality metrics and automated quality calibrations (i.e., automated and random selection of work assignment/transactions for comparison to standards). Additionally, the quality assurance system provides for validating the quality assurance work by random sampling and quality assurance assessment of the auditor's work and an associate improvement plan, whereby quality assurance metrics may be systematically adjusted and/or sampling sizes increased for associates with quality scores that dictate a need for improvement.

Abstract: An end-to-end, centralized and globally-accessible platform for work assignment input, allocation, performance and tracking is herein described. The platform is configured to improve operational and quality assurance effectiveness and efficiency through automated work allocation, performance tracking and reporting. The end-to-end approach accounts for work assignment input, work assignment allocation, work assignment processing and quality assessment and assurance of the completed work assignments. In addition, both automated and manual work assignment allocations from both an operation (i.e., work input and allocation) perspective, as well as, a quality assurance perspective are possible.

Abstract: The invention provides conjugate-based antifungal or antibacterial prodrugs formed by coupling at least one anti-fungal agent or antibacterial agent with at least one linker and/or carrier. The prodrugs are of formula: (i) (AFA)m-X-(L)n; (ii) [(AFA)m?-X]p-L; (iii) AFA-[X-(L)n?]q; or (iv) (AFA)m?-X, wherein: AFA is an antifungal agent or an antibacterial agent; L is a carrier; X is a linker; m ranges from 1 to 10; n ranges from 2 to 10; m? is 1 to 10; p is 1 to 10; n? is 1 to 10; and q is 1 to 10, provided that q? and n are not both 1; and m? is 1 to 10. The invention also provides nanoparticles comprising the conjugate-based prodrugs. Additionally, the invention also provides non-conjugated antifungal and antibacterial agents in the form of nanoparticles.

Abstract: Compositions, systems and methods of sequencing are disclosed, where the compositions and systems include polymerase enzymes that have been genetically modified to more efficiently incorporate nucleotides including labels having a detectable properties that are released during incorporation, to augment a rate of labeled nucleotide incorporation, to augment a rate of pyrophosphate release, or to augment two or more of these properties and rates. Also disclosed are terminally labeled and dual labeled nucleotides, and click-chemistry based methods of synthesizing the same.

Abstract: In a system for bridging one or more legacy systems with one or more component systems for data communication, a method for integrating application processes with one another includes steps for (a) expressing all application behavior using a modeling language; (b) transforming those expressions into process automata; (c) organizing composition settings comprising the process automata; and (d) analyzing process automata for integration safety and for integration completeness properties of the process automata using a deterministic finite automata library and leveraging its base functions.

Abstract: An apparatus and method of mapping a file name to a computer system in a network of computer systems are provided. In a first embodiment, a list of names of the computer systems starting with a root name is created. The filename itself starts with a root name and consists of an aggregation of names. When the filename is obtained, each name is matched one at a time and in the order of appearance to the names in the list. In order for a match, the order of appearance of the names in the list of names and that of the names in the filename must be the same. The last name in the list of names to be matched with a name in the filename represents a computer system within which the file is contained. In a second embodiment, the list of names is in the form of a tree of names. Matching the names of the tree to the names in the filename includes traversing a branch of that tree to a leaf node, the leaf node being the last node in the tree.

Abstract: A separate window is provided for each of multiple OpenDoc Canvas objects, thereby effecting a multiple Canvas-per-compound document design. Possibility of one OpenDoc object drawing in another object's screen area is eliminated by clipping imposed by the graphics engine on a per-window basis. Multiple different rendering libraries may be employed for screen imaging. The raw window may be used for direct platform-specific drawing functions and other rendering toolkits. User interface elements associated with alternative graphical user interfaces may be used as the root of a window hierarchy. A PlatformCanvas represents a handle to platform-dependent data types which are passed directly to native drawing routines and which provides a generic entity for specifically handling platform-specific architectures, providing a generic representation of platform-specific structures.