Patents by Inventor Sreejayan Nair

Sreejayan Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating wounds using cathepsin K inhibitors
    Patent number: 11766467
    Abstract: Diabetic wounds have elevated levels of cathepsin K, a protease enzyme, which degrades proteins, such as collagen, causing delayed wound healing. By targeting cathepsin K, diabetic wound healing is ameliorated. Methods and devices for treatment include intradermal injection of odanacatib at or adjacent a wound. Methods and devices for treatment include topical application of pharmacological inhibitors of cathepsin K, for example, in the form of gel, powder, or bandage. Other methods and systems include localized genetic knock out of the cathepsin K gene by topical application of a small interfering RNA (siRNA) or antisense oligonucleotide to aid in wound healing.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: September 26, 2023
    Assignee: University of Wyoming
    Inventor: Sreejayan Nair
  • Methods of Treating Wounds Using Cathepsin K Inhibitors
    Publication number: 20200390848
    Abstract: Diabetic wounds have elevated levels of cathepsin K, a protease enzyme, which degrades proteins, such as collagen, causing delayed wound healing. By targeting cathepsin K, diabetic wound healing is ameliorated. Methods and devices for treatment include intradermal injection of odanacatib at or adjacent a wound. Methods and devices for treatment include topical application of pharmacological inhibitors of cathepsin K, for example, in the form of gel, powder, or bandage. Other methods and systems include localized genetic knock out of the cathepsin K gene by topical application of a small interfering RNA (siRNA) or antisense oligonucleotide to aid in wound healing.
    Type: Application
    Filed: August 28, 2020
    Publication date: December 17, 2020
    Applicant: University of Wyoming
    Inventor: Sreejayan Nair
  • Targeting cathepsin K to facilitate wound healing
    Patent number: 10758559
    Abstract: Diabetic wounds have elevated levels of cathepsin K, a protease enzyme, which degrades proteins, such as collagen, causing delayed wound healing. By targeting cathepsin K, diabetic wound healing is ameliorated. Methods and devices for treatment include topical application of pharmacological inhibitors of cathepsin K, for example, in the form of gel, powder, or bandage. Other methods and systems include localized genetic knock out of the cathepsin K gene by topical application of a small interfering RNA (siRNA) or antisense oligonucleotide to aid in wound healing.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: September 1, 2020
    Assignee: University of Wyoming
    Inventor: Sreejayan Nair