Patents by Inventor Sridaran Natesan

Sridaran Natesan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR MEASURING RESISTANCE OR SENSITIVITY TO DOCETAXEL
    Publication number: 20130252837
    Abstract: The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient's response to a molecule of the taxoid family by measuring nucleic acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 26, 2013
    Applicant: Sanofi US
    Inventors: Dorre GRUENEBERG, Xi HUANG, Sridaran NATESAN, Paul AUGUST
  • Composition and method for treatment of tumors
    Patent number: 8329669
    Abstract: The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: December 11, 2012
    Assignee: Sanofi
    Inventors: Paul August, Waan Jeng Huang, Sridaran Natesan, Soyan Lieberman
  • COMPOSITION AND METHOD FOR TREATMENT OF TUMORS
    Publication number: 20100035807
    Abstract: The present invention relates to a composition which is useful in the treatment of a tumor, a method for making such a composition, and a method for using such a composition. The invention relates also to a method for assaying for inhibitors of the activity of Core 1 protein and/or other proteins of the respiratory complex III of mitochondria.
    Type: Application
    Filed: July 25, 2007
    Publication date: February 11, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Paul August, Waan Jeng Huang, Sridaran Natesan, Soyan Lieberman
  • METHOD FOR MEASURING RESISTANCE OR SENSITIVITY TO DOCETAXEL
    Publication number: 20090226894
    Abstract: The present invention relates to novel and useful methods that predict or monitor a patient's response to a molecule of the taxoid family by measuring the increase or decrease of specific genetic markers as compared to controls. The present invention also provides kits that predict of monitor patient's response to a molecule of the taxoid family by measuring nucleid acid or protein levels of particular genetic markers and comparing their levels to controls or reference markers.
    Type: Application
    Filed: December 1, 2005
    Publication date: September 10, 2009
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Dorre Grueneberg, Xi Huang, Sridaran Natesan, Paul August
  • Mitotic Progression Genes and Methods of Modulating Mitosis
    Publication number: 20090215876
    Abstract: The invention features methods of identifying candidate therapeutic compounds for the treatment of proliferative disorder. The invention also features methods for treating a proliferative disorder.
    Type: Application
    Filed: February 14, 2007
    Publication date: August 27, 2009
    Inventors: Randall W. King, Susan K. Lyman, Eunah Chung, Sridaran Natesan, Charles B. Epstein
  • Methods Of Treating Demyelinating Disorders
    Publication number: 20070280885
    Abstract: Methods of identifying and using compounds capable of treating demyelinating disorders such as multiple sclerosis by inhibiting EphB1-mediated cell repulsion of CNS and PNS glial cells (oligodendrocytes and Schwann cells and progenitor cells within these lineages).
    Type: Application
    Filed: May 4, 2005
    Publication date: December 6, 2007
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Karen Chandross, Jean Merrill, Sridaran Natesan
  • Use of heterologous transcription factors in gene therapy
    Publication number: 20030143731
    Abstract: This invention provides novel materials and methods involving the heterologous expression of transcription factors which are useful for effecting transcription of target genes in genetically engineered cells or organisms containing them. Target gene constructs and other materials useful for practicing the invention are also disclosed.
    Type: Application
    Filed: October 23, 2001
    Publication date: July 31, 2003
    Applicant: ARIAD Gene Therapeutics, Inc.
    Inventors: Michael Z. Gilman, Sridaran Natesan
  • Compositions and method for regulation of transcription
    Patent number: 6479653
    Abstract: The present invention relates to novel fusion proteins which activate transcription, to nucleic acid constructs encoding the proteins and their use in the genetic engineering of cells.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: November 12, 2002
    Assignee: ARIAD Gene Therapeutics, Inc.
    Inventors: Sridaran Natesan, Michael Z. Gilman
  • Methods and materials for regulated production of proteins
    Publication number: 20020048792
    Abstract: This invention provides methods and materials for regulated production of proteins.
    Type: Application
    Filed: July 16, 2001
    Publication date: April 25, 2002
    Applicant: ARIAD Gene Therapeutics, Inc.
    Inventors: Sridaran Natesan, Timothy P. Clackson, Roy M. Pollock
  • Heterologous transcription factors
    Patent number: 6306649
    Abstract: This invention provides novel materials and methods involving the heterologous expression of transcription factors which are useful for effecting transcription of target genes in genetically engineered cells or organisms containing them. Target gene constructs and other materials useful for practicing the invention are also disclosed.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: October 23, 2001
    Assignee: ARIAD Gene Therapeutics, Inc.
    Inventors: Michael Z. Gilman, Sridaran Natesan
  • Compositions and methods for regulation of transcription
    Patent number: 6117680
    Abstract: The present invention relates to novel fusion proteins which activate transcription, to nucleic acid constructs encoding the proteins and their use in the genetic engineering of cells.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: September 12, 2000
    Assignee: ARIAD Gene Therapeutics, Inc.
    Inventors: Sridaran Natesan, Michael Z. Gilman
  • Transcriptional activators, and compositions and uses related thereto
    Patent number: 6015709
    Abstract: The present invention relates to chimeric transcriptional activators.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: January 18, 2000
    Assignee: ARIAD Pharmaceuticals, Inc.
    Inventor: Sridaran Natesan