Patents by Inventor Sridhar Peddi

Sridhar Peddi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyanoamidine P2Xantagonists for the treatment of pain
    Patent number: 7241776
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: July 10, 2007
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan S. Florjancic
  • P2X7 receptor antagonists and methods of use
    Publication number: 20070105842
    Abstract: The invention is directed to compounds that are P2X7 antagonist and have the formula (I) or (II) or a pharmaceutically acceptable salt, prodrug, salt of a prodrug or a combination thereof, wherein R1, R2, and R3 are defined in the specification. The invention is also directed to a method of selectively inhibiting P2X7 activity comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound of formula (III), (IV) or (V) wherein R6, R7, R8, R9, R10, and R11 are defined in the specification.
    Type: Application
    Filed: November 6, 2006
    Publication date: May 10, 2007
    Inventors: William Carroll, Alan Florjancic, Arturo Perez-Medrano, Sridhar Peddi
  • Amino-tetrazoles analogues and methods of use
    Publication number: 20070049584
    Abstract: A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: April 29, 2005
    Publication date: March 1, 2007
    Inventors: William Carroll, Arturo Perez-Medrano, Alan Florjancic, Derek Nelson, Sridhar Peddi, Tongmei Li, Eric Bunnelle, Gavin Hirst, Biquin Li
  • Amino-tetrazole analogues and methods of use
    Publication number: 20060052374
    Abstract: A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: September 7, 2005
    Publication date: March 9, 2006
    Inventors: William Carroll, Arturo Perez-Medrano, Alan Florjancic, Derek Nelson, Sridhar Peddi, Tongmei Li, Eric Bunnelle, Gavin Hirst, Biquin Li
  • Cyanoamidine P2X7 antagonists for the treatment of pain
    Publication number: 20060025614
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Application
    Filed: August 2, 2004
    Publication date: February 2, 2006
    Inventors: William Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan Florjancic
  • P2X7 antagonists for treating neuropathic pain
    Publication number: 20050171195
    Abstract: The present invention discloses a method for treating neuropathic pain using compounds of formula I or compositions containing compounds of formula I.
    Type: Application
    Filed: November 3, 2004
    Publication date: August 4, 2005
    Inventors: William Carroll, Arturo Medrano, Michael Jarvis, Ying Wang, Sridhar Peddi