Abstract: A redriver system adapted for coupling to a first device and to a second device includes first and second transmitter drivers and a snoop circuit. The first transmitter driver has a first enable input. The second transmitter driver has a second enable input. The snoop circuit is coupled to the first and second enable inputs. The snoop circuit is configured to determine whether the first device and the second device are to operate according to a first protocol. Responsive to the snoop circuit determining that the first and second devices are to operate according to the first protocol, the snoop circuit enables the first transmitter driver and disables the second transmitter driver. Responsive to the snoop circuit determining that the first and second devices are not to operate according to the first protocol, the snoop circuit disables the first transmitter driver and enables the second transmitter driver.

Abstract: An example apparatus includes an account information circuit structured to interpret identifying information for a seller blockchain account and for each one of at least one buyer blockchain account, the identifying information for each one of the at least one buyer blockchain account including an attribute interest value. An apparatus further includes an asset attribute circuit structured to interpret an asset attribute value for an asset associated with the seller blockchain account. An apparatus further includes a buyer interest circuit structured to determine a buyer interest value for each one of the at least one buyer blockchain account in response to each corresponding attribute interest value and the asset attribute value. An apparatus includes a buyer identification execution circuit structured to perform a buyer identification operation in response to the buyer interest value.

Abstract: An example apparatus includes an account information circuit structured to interpret first identifying information for a first blockchain account and second identifying information for a second blockchain account, the first identifying information including a trust rating value, and the second identifying information including a transaction confirmation value corresponding to a transaction between the first blockchain account and the second blockchain account. An apparatus includes a trust value adjustment circuit structured to interpret a transaction rating value from a user associated with the second blockchain account, and to adjust the trust rating value in response to the transaction rating value and the transaction confirmation value. An apparatus includes an account trust matching execution circuit structured to perform an account trust operation in response to the adjusted trust rating value.

Abstract: An example apparatus includes a blockchain monitoring circuit structured to interpret a blockchain index data structure comprising a plurality of attribute values for each of a plurality of assets associated with a blockchain. An apparatus includes a blockchain asset ranking circuit structured to determine an asset rank value for each asset of the plurality of assets and includes a blockchain transaction assistant circuit structured to, in response to the asset rank value for each asset, perform at least one operation selected from: provide an asset ranking communication to a user interface for transactions associated with the blockchain; or store the asset rank value for each asset of the plurality of assets on the blockchain index data structure.

Abstract: An example apparatus includes a blockchain data circuit that interprets a blockchain description value, a blockchain index circuit that provides a blockchain index data structure in response to the blockchain description value, the blockchain index data structure including a number of attribute values for each of a number of entities associated with the blockchain description value, and a blockchain search circuit that exercises a user interface. The user interface allows for interpreting a user search value, and the blockchain search circuit provides a search description to the user interface in response to the user search value and the blockchain index data structure.

Abstract: A method for forecasting part sales, including collecting sales data for a part over a series of sales time periods and collecting activity data for a plurality of activity types over a series of activity time periods for a plurality of machines including the part. A mean activity time can be calculated for each activity type for each time period in the series of activity time periods based on the collected activity data. An activity probability density function of the mean activity times for each activity type is created and a machine learning model is trained using an expectation of activity derived from the probability density functions for each activity type and the collected sales data. Machine activity data for a set of machines can be fed into the trained model to derive a part sales probability density function for the set of machines.

Abstract: A redriver system adapted for coupling to a first device and to a second device includes first and second transmitter drivers and a snoop circuit. The first transmitter driver has a first enable input. The second transmitter driver has a second enable input. The snoop circuit is coupled to the first and second enable inputs. The snoop circuit is configured to determine whether the first device and the second device are to operate according to a first protocol. Responsive to the snoop circuit determining that the first and second devices are to operate according to the first protocol, the snoop circuit enables the first transmitter driver and disables the second transmitter driver. Responsive to the snoop circuit determining that the first and second devices are not to operate according to the first protocol, the snoop circuit disables the first transmitter driver and enables the second transmitter driver.

Abstract: The present invention provides methods of treatment of cancer patients having deficiency in at least one non-BRCA1/2 gene involved in the homologous recombination repair (HRR) pathway with a poly(ADP-ribose) polymerase (PARP) inhibitor such as niraparib. In particular, cancer patients having a deficiency in at least one gene selected from the group consisting of BRCA1, BRCA2, ATM, ATR, BAP1, BARD1, BLM, BRIP1, MRE11A, NBN, PALB2, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, XRCC2, TP53, or RBI can benefit from treatment with niraparib.

Abstract: Aspects of the disclosure relate to enabling independent storage and processing of data with centralized event control. An event control computing platform may receive an indicator of a processing task associated with processing a dataset. Subsequently, the event control computing platform may authenticate the indicator of the processing task. Then the event control computing platform may identify and allocate resources for executing the processing task and storing the dataset. Finally, the event control computing platform may generate and transmit a series of commands to cause the dataset to be accessed by the processing platform, cause the processing task associated with the dataset to be executed, and cause the processed dataset to be stored on the storage platform.

Abstract: Methods, systems, and apparatus include computer programs encoded on a computer-readable storage medium, including a system including a search engine server that provides a search user interface. The search user interface includes a search field that enables a user to submit a search request as well as a set of contextual labels that enable a user to specify, through interaction with one of multiple different presented contextual labels, a topical context for the search request. The search engine server identifies a set of search results using the search request and the topical context for the search request. The system also includes a content server that identifies additional content related to both the search request and the topical context and provides the identified additional content for presentation with the set of search results in the search user interface.

Abstract: Aspects of the disclosure relate to enabling independent storage and processing of data with centralized event control. An event control computing platform may receive an indicator of a processing task associated with processing a dataset. Subsequently, the event control computing platform may authenticate the indicator of the processing task. Then the event control computing platform may identify and allocate resources for executing the processing task and storing the dataset. Finally, the event control computing platform may generate and transmit a series of commands to cause the dataset to be accessed by the processing platform, cause the processing task associated with the dataset to be executed, and cause the processed dataset to be stored on the storage platform.

Abstract: Aspects of the disclosure relate to enabling independent storage and processing of data with centralized event control. An event control computing platform may receive an indicator of a processing task associated with processing a dataset. Subsequently, the event control computing platform may authenticate the indicator of the processing task. Then the event control computing platform may identify and allocate resources for executing the processing task and storing the dataset. Finally, the event control computing platform may generate and transmit a series of commands to cause the dataset to be accessed by the processing platform, cause the processing task associated with the dataset to be executed, and cause the processed dataset to be stored on the storage platform.

Abstract: Aspects of the disclosure relate to enabling independent storage and processing of data with centralized event control. An event control computing platform may receive an indicator of a processing task associated with processing a dataset. Subsequently, the event control computing platform may authenticate the indicator of the processing task. Then the event control computing platform may identify and allocate resources for executing the processing task and storing the dataset. Finally, the event control computing platform may generate and transmit a series of commands to cause the dataset to be accessed by the processing platform, cause the processing task associated with the dataset to be executed, and cause the processed dataset to be stored on the storage platform.

Abstract: Provided herein are methods and compositions related to modulation of the rate of asymmetric proliferation of cancer cells. In some embodiments, the methods described herein relate to the treatment of cancer, at least in part, via the modulation of the rate of asymmetric proliferation of cancer cells.

Abstract: Provided herein are methods and assays that can be used to predict whether a subject will or will not respond to a cancer treatment comprising a PARP inhibitor and a DNA damage-inducing chemotherapeutic.

Abstract: A phase detector and retimer circuit that includes a retimer circuit, a phase shift circuit coupled to the retimer circuit, and an error signal generation circuit coupled to the retimer circuit and the phase shift circuit. The retimer circuit is configured to receive a data signal and generate a first retimed data signal based on a first phase of a clock signal and a second retimed data signal based on a second phase of the clock signal. The phase shift circuit is configured to receive the data signal and phase shift the data signal to generate first, second, third, and fourth phase shifted data signals. The error signal generation circuit is configured to generate a first error signal and a second error signal based on the first and second retimed data signals and the first, second, third, and fourth phase shifted data signals.

Abstract: The usefulness, and consequently the performance, of advertisements are improved by allowing businesses to better target their ads to a responsive audience. Location information is determined (or simply accepted) and used. For example, location information may be used in a relevancy determination of an ad. As another example, location information may be used in an attribute (e.g., position) arbitration. Such location information may be associated with price information, such as a maximum price bid. Such location information may be associated with ad performance information. Ad performance information may be tracked on the basis of location information. The content of an ad creative, and/or of a landing page may be selected and/or modified using location information. Tools, such as user interfaces, may be provided to allow a business to enter and/or modify location information. The location information used to target and/or score ads may be, include, or define an area.

Abstract: A loss of lock detector that includes a logic gate, a voltage-to-current converter coupled to the logic gate, a capacitor coupled to the converter, and a comparator coupled to the capacitor. The logic gate is configured to receive a first error signal and a second error signal from a phase detector, perform an AND function of the first and second error signals, and generate a gate output signal. The converter is configured to receive the gate output signal and generate a stream of current pulses representative of the gate output signal. The capacitor is configured to receive the stream of current pulses and generate a DC signal representative of the stream of current pulses. The comparator is configured to compare the DC signal to a reference signal and output a lock signal.

Abstract: Methods, systems, and apparatus include computer programs encoded on a computer-readable storage medium, including a system including a search engine server that provides a search user interface. The search user interface includes a search field that enables a user to submit a search request as well as a set of contextual labels that enable a user to specify, through interaction with one of multiple different presented contextual labels, a topical context for the search request. The search engine server identifies a set of search results using the search request and the topical context for the search request. The system also includes a content server that identifies additional content related to both the search request and the topical context and provides the identified additional content for presentation with the set of search results in the search user interface.

Abstract: A phase-frequency detector (PFD) circuit that includes a binary phase detector and a ternary phase detector coupled to the binary phase detector. The binary phase detector is configured to, based on the PFD circuit being in a frequency acquisition state, compare a clock signal with a data signal and output up and down signals based on the comparison. The binary phase detector is also configured to be disabled based on the PFD circuit being in a frequency locked state. The ternary phase detector is configured to compare the clock signal with the data signal and output up, down, and hold signals based on the comparison.