Patents by Inventor Sridharan Rajamani

Sridharan Rajamani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound and methods for treating long QT syndrome
    Patent number: 9126989
    Abstract: Described herein is a method of treating long QT syndrome by administration of an effective amount of a potent and selective late sodium ion channel blocker.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: September 8, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Sridharan Rajamani, Dewan Zeng
  • COMBINATION THERAPIES USING LATE SODIUM ION CHANNEL BLOCKERS AND POTASSIUM ION CHANNEL BLOCKERS
    Publication number: 20150045305
    Abstract: Described herein is a method for the treatment or prevention of atrial fibrillation and/or atrial flutter comprising administration of an effective amount of one or more of a potassium channel blocker and an effective amount of one or more of a late sodium channel blocker. Also provided are methods for modulating ventricular and atrial rhythm and rate. Also provided are pharmaceutical formulations that are suitable for such combined administration.
    Type: Application
    Filed: January 25, 2013
    Publication date: February 12, 2015
    Inventors: Luiz Belardinelli, Sridharan Rajamani
  • COMPOUND AND METHODS FOR TREATING LONG QT SYNDROME
    Publication number: 20150038489
    Abstract: Described herein is a method of treating long QT syndrome by administration of an effective amount of a potent and selective late sodium ion channel blocker
    Type: Application
    Filed: July 31, 2014
    Publication date: February 5, 2015
    Applicant: Gilead Sciences, Inc.
    Inventors: Luiz Belardinelli, Sridharan Rajamani, Dewan Zeng
  • RANOLAZINE FOR THE TREATMENT OF CNS DISORDERS
    Publication number: 20100292217
    Abstract: The present invention relates to a method for CNS disorders such as epilepsy and migraine comprising the administration of a therapeutically effective amount of ranolazine.
    Type: Application
    Filed: May 13, 2010
    Publication date: November 18, 2010
    Applicant: Gilead Palo Alto, Inc.
    Inventors: Luiz Belardinelli, Alfred George, Kristopher Kahlig, Sridharan Rajamani
  • METHOD OF TREATING ATRIAL FIBRILLATION
    Publication number: 20100056536
    Abstract: The present invention relates to a method for the treatment of atrial fibrillation comprising the coadministration of a synergistic therapeutically effective amount of amiodarone and synergistic therapeutically effective amount ranolazine. This invention also relates to pharmaceutical formulations that are suitable for such combined administration.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 4, 2010
    Inventors: Charles Antzelevitch, Alexander Burashnikov, John Shryock, Sridharan Rajamani, Luiz Belardinelli
  • METHODS FOR TREATING PAIN
    Publication number: 20090203707
    Abstract: This invention relates to methods for treating a patient suffering from neuropathic or nociceptive pain which may be mechanical, visceral, and/or inflammatory in nature, comprising administering a therapeutically effective amount of Ranolazine to a patient in need thereof.
    Type: Application
    Filed: February 6, 2009
    Publication date: August 13, 2009
    Inventors: Sridharan Rajamani, John Shryock, Ivan Diamond, Luiz Belardinelli
  • REDUCTION OF CARDIOVASCULAR SYMPTOMS
    Publication number: 20080153840
    Abstract: The present application discloses methods for treating patients with a dysfunction of the ion channels of the heart suffering from one or more cardiovascular diseases to reduce the proarrhythmic effect of drugs and/or conditions that reduce or inhibit IKr.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 26, 2008
    Inventors: Luiz Belardinelli, Lin Wu, Sridharan Rajamani, Arvinder Dhalla