Patents by Inventor Srigiridhar Kotamraju

Srigiridhar Kotamraju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-INFLAMMATORY COMPOUNDS FOR USE IN THE TREATMENT OF DERMAL DISORDERS
    Publication number: 20220296618
    Abstract: The present invention relates to the use of a compound of Formula (I) for the treatment of a wound, impaired healing of a wound, hair loss on and around a wound, scars and/or wrinkles on and around a wound, psoriasis, and any combination thereof. The present inventions also relates to methods of using such compounds, and to compositions and kits containing the compound. (I) X? is any halogen.
    Type: Application
    Filed: November 23, 2020
    Publication date: September 22, 2022
    Inventors: Srigiridhar KOTAMRAJU, Surendar Reddy BATHULA, Ramakrishna SISTLA, Anthony ADDLAGATTA, Rajamannar THENNATI, Altab SHAIKH, Aruna JANGUM, Rajendra SANGARAJU, Praveen Kumar NEELI, Kuncha MADHUSUDANA, Singuru GAJALAKSHMI
  • Indole (sulfomyl) n-hydroxy benzamide derivatives as selective HDAC inhibitors
    Patent number: 11072583
    Abstract: Sulfonyl hydroxamic acid compounds have the following general formula: Ring A and B are aryl, heteroaryl, cycloalkyl, fused aryl or fused alkyl group, and R1, R2, R3, R4, R5, and R6 are hydrogen, alkoxy, aryloxy, hydroxy, ester, amide, amino, alkyl, aryl, heteroaryl, halogen, hydroxy, alkoxy, aryloxy, nitro, cyano, ester, or aldehyde. The compounds are HDAC inhibitors. Processes can be used for preparation of these indole-based sulfonyl hydroxamic acid derivatives.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: July 27, 2021
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Chandrasekhar Srivari, Prathama Satyendra Mainkar, Chada Raji Reddy, Srigiridhar Kotamraju, Pavan Kumar Togapur, Subbarao Mohan Venkata Muppidi, Somesh Sharma, Ashok Kumar Jha, Prem Kumar Arumugam
  • INDOLE (SULFOMYL) N-HYDROXY BENZAMIDE DERIVATIVES AS SELECTIVE HDAC INHIBITORS
    Publication number: 20200385349
    Abstract: Sulfonyl hydroxamic acid compounds have the following general formula: Ring A and B are aryl, heteroaryl, cycloalkyl, fused aryl or fused alkyl group, and R1, R2, R3, R4, R5, and R6 are hydrogen, alkoxy, aryloxy, hydroxy, ester, amide, amino, alkyl, aryl, heteroaryl, halogen, hydroxy, alkoxy, aryloxy, nitro, cyano, ester, or aldehyde. The compounds are HDAC inhibitors. Processes can be used for preparation of these indole-based sulfonyl hydroxamic acid derivatives.
    Type: Application
    Filed: August 6, 2018
    Publication date: December 10, 2020
    Inventors: Chandrasekhar SRIVARI, Prathama Satyendra MAINKAR, Chada Raji REDDY, Srigiridhar KOTAMRAJU, Pavan Kumar TOGAPUR, Subbarao Mohan Venkata MUPPIDI, Somesh SHARMA, Ashok Kumar JHA, Prem Kumar ARUMUGAM
  • C5, C6 substituted and/or fused oxindoles as anti-cancer agents and process for preparation thereof
    Patent number: 10343991
    Abstract: The present invention describes the C5,C6 Substituted and/or fused oxindole compounds useful as anti-cancer agents and process for preparation thereof. Particularly the present invention relates to C5,C6 Substituted and/or fused oxindole compounds of formula I.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: July 9, 2019
    Assignee: Council of Scientific & Industrial Research
    Inventors: Raji Reddy Chada, Srigiridhar Kotamraju, Santosh Karnewar, Nagendra Babu Bathini, Nagarsenkar Atulya, Anuradha Singampalli
  • C5, C6 SUBSTITUTED AND/OR FUSED OXINDOLES AS ANTI-CANCER AGENTS AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20180127365
    Abstract: The present invention describes the C5,C6 Substituted and/or fused oxindole compounds useful as anti-cancer agents and process for preparation thereof. Particularly the present invention relates to C5,C6 Substituted and/or fused oxindole compounds of formula I.
    Type: Application
    Filed: November 2, 2017
    Publication date: May 10, 2018
    Inventors: Raji Reddy CHADA, Srigiridhar Kotamraju, Santosh Karnewar, Nagendra Babu Bathini, Nagarsenkar Atulya, Anuradha Singampalli
  • Methods for Treating Cancer
    Publication number: 20070219208
    Abstract: It is disclosed here that HMG-CoA reductase inhibitors inhibit the proliferation and cause the death of breast cancer cells by inducing the expression of inducible nitric oxide synthase (iNOS) to promote intracellular nitric oxide formation, which the inventors found to be accomplished through the inhibition of protein geranylgeranylation. The disclosure here enables a new breast cancer treatment strategy that combines the inhibition HMG-CoA reductase or protein geranylgeranylation and the promotion of nitric oxide formation by iNOS.
    Type: Application
    Filed: February 22, 2007
    Publication date: September 20, 2007
    Inventors: Balaraman Kalyanaraman, Srigiridhar Kotamraju