Patents by Inventor SRINATH BALAJI

SRINATH BALAJI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystallization process of tricyclic indole derivatives
    Patent number: 10709798
    Abstract: A composition comprising a tricyclic indole compound. The composition has a higher purity and better impurity profile than known compositions comprising said tricyclic indole compound and as a consequence has superior properties, particularly when said compound is destined for use in vivo as a therapeutic or diagnostic agent.
    Type: Grant
    Filed: November 28, 2013
    Date of Patent: July 14, 2020
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Sondre Nilsen, Srinath Balaji Aralikatti Prahladachar Balaji, Umamaheshwar P. Mokkapati, Afsal Mohammed Kadavilpparampu Mohamed
  • CRYSTALLIZATION PROCESS OF TRICYCLIC INDOLE DERIVATIVES
    Publication number: 20150335766
    Abstract: A composition comprising a tricyclic indole compound. The composition has a higher purity and better impurity profile than known compositions comprising said tricyclic indole compound and as a consequence has superior properties, particularly when said compound is destined for use in vivo as a therapeutic or diagnostic agent.
    Type: Application
    Filed: November 28, 2013
    Publication date: November 26, 2015
    Inventors: Sondre NILSEN, Srinath Balaji Aralikatti Prahladachar Balaji, Umamaheshwar P. MOKKAPATI, Afsal, Mohammed KADAVILPPARAMPU, MOHAMED
  • NOVEL SYNTHESIS METHOD
    Publication number: 20150133663
    Abstract: The present invention relates to a method of making compounds having affinity for the 1 A subtype of the serotonin receptor, i.e. 5HT1A. The method of the present invention provides advantages over the known methods of synthesis. The compounds obtained by the method of the invention have use in therapeutic methods. The compounds of the invention may also optionally compose a moiety suitable for detection by an in vivo imaging procedure and as such these compounds have use in in vivo imaging methods. The compounds have particular use in the treatment and diagnosis of various neurological and/or psychiatric disorders.
    Type: Application
    Filed: September 21, 2012
    Publication date: May 14, 2015
    Inventors: Radha Achanath, Jinto Jose, Chitralekha Rangaswamy, Subrata Mandal, Afsal Mohammed Kadivilpparampu Mohamed, Ian Martin Newington, Srinath Balaji
  • Precursor compounds and methods for making same
    Patent number: 8946483
    Abstract: The present invention relates to a method of obtaining radiopharmaceutical precursors, and in particular precursors to protected amino acid derivatives, which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging procedures, such as positron emission tomography (PET).
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: February 3, 2015
    Assignee: GE Healthcare Limited
    Inventors: Radha Achhanath, Srinath Balaji, Asfal Mohammed Kadavilpparampu Mohamed, Sondre Nilsen, Steven Michael Fairway
  • PRECURSOR COMPOUNDS AND METHODS FOR MAKING SAME
    Publication number: 20140135531
    Abstract: The present invention relates to a method of obtaining radiopharmaceutical precursors, and in particular precursors to protected amino acid derivatives, which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging procedures, such as positron emission tomography (PET).
    Type: Application
    Filed: July 20, 2012
    Publication date: May 15, 2014
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Radha Achhanath, Srinath Balaji, Asfal Mohammed Kadavilpparampu Mohamed, Sondre Nilsen, Steven Michael Fairway
  • Active enantiomer
    Patent number: 8501153
    Abstract: The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: August 6, 2013
    Assignee: GE Healthcare Limited
    Inventors: Radha Achanath, Srinath Balaji, Afsal M. Kadavilpparampu Mohamed, Umamaheshwar Mokkapati, Steven Fairway, Dimitrios Mantzilas, Dennis O'Shea, William John Trigg, Harry John Wadsworth, Joanna Marie Passmore, Bo Shan
  • DYE COMPOSITIONS AND DYE SYNTHESES
    Publication number: 20130121926
    Abstract: The present invention relates to sulfonated optical dye compositions, especially dyes suitable for biological applications in vitro, and for in vivo imaging. Improved dye compositions and intermediates are provided, which enable the suppression of undesirable newly-identified impurities. Also provided is the use of the improved dye compositions in the preparation of conjugates with biological targeting molecules.
    Type: Application
    Filed: June 29, 2011
    Publication date: May 16, 2013
    Applicant: GE HEALTHCARE AS
    Inventors: Radha Achanath, Srinath Balaji, John Henrik Johansen
  • ACTIVE ENANTIOMER
    Publication number: 20110070161
    Abstract: The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 24, 2011
    Applicant: GE HEALTHCARE LIMITED
    Inventors: RADHA ACHANATH, SRINATH BALAJI, STEVEN FAIRWAY, AFSAL M. KADAVILPPARAMPU MOHAMED, DIMITRIOS MANTZILAS, UMAMAHESHWAR MOKKAPATI, DENNIS O'SHEA, JOANNA MARIE PASSMORE, BO SHAN, WILLIAM JOHN TRIGG, HARRY JOHN WADSWORTH