Patents by Inventor Srini RAMANATHAN

Srini RAMANATHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE TREATMENT OF THYROID EYE DISEASE
    Publication number: 20260217838
    Abstract: Provided herein are methods of treating or reducing the severity of thyroid eye disease (TED), also known as thyroid-associated ophthalmopathy (TAO), or Graves' ophthalmopathy or orbitopathy (GO), as well as antibodies, or antigen binding fragments thereof, and pharmaceutical compositions comprising them, useful in the methods.
    Type: Application
    Filed: April 6, 2026
    Publication date: July 30, 2026
    Applicant: Horizon Therapeutics Ireland DAC
    Inventors: Jeffrey W. SHERMAN, Dennis A. BENNETT, Srini RAMANATHAN, Yan XIN, Elizabeth THOMPSON, Elizabeth O'NEILL
  • Methods for the treatment of thyroid eye disease
    Patent number: 12600787
    Abstract: Provided herein are methods of treating or reducing the severity of thyroid eye disease (TED), also known as thyroid-associated ophthalmopathy (TAO), or Graves' ophthalmopathy or orbitopathy (GO), as well as antibodies, or antigen binding fragments thereof, and pharmaceutical compositions comprising them, useful in the methods.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: April 14, 2026
    Assignee: Horizon Therapeutics Ireland DAC
    Inventors: Jeffrey W. Sherman, Dennis A. Bennett, Srini Ramanathan, Yan Xin, Elizabeth Thompson, Elizabeth O'Neill
  • ANTI-TL1A ANTIBODY THERAPEUTIC METHODS
    Publication number: 20260078194
    Abstract: The present disclosure provides methods and compositions for determining the risk of a patient being non-responsive to a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody and methods and compositions for treating inflammatory bowel disease (IBD) with a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody.
    Type: Application
    Filed: November 14, 2025
    Publication date: March 19, 2026
    Inventors: Sudhir PENUGONDA, Srini RAMANATHAN, Jason CHAMBERLAIN, Keith HAAN, Mayukh SUKHATME, Frank TORTI, Christopher Ricardo BANFIELD, Deepa E. CHANDRA, Mina HASSAN-ZAHRAEE, Xinli HU, Kenneth HUNG, Craig L. HYDE, Steven W. MARTIN, Srividya NEELAKANTAN, Elena PEEVA, Michael S. VINCENT, Ying WU, Zhan YE
  • METHODS FOR THE TREATMENT OF SCLERODERMA AND RELATED CONDITIONS
    Publication number: 20240279323
    Abstract: Provided herein are antibodies against insulin-like growth factor 1 receptor (IGF-1R) and their use in methods of treatment of, and achievement of clinical outcomes in, scleroderma and forms thereof, including diffuse cutaneous systemic sclerosis.
    Type: Application
    Filed: February 8, 2024
    Publication date: August 22, 2024
    Inventors: Elizabeth THOMPSON, Srini RAMANATHAN
  • METHODS FOR THE TREATMENT OF THYROID EYE DISEASE
    Publication number: 20220356257
    Abstract: Provided herein are methods of treating or reducing the severity of thyroid eye disease (TED), also known as thyroid-associated ophthalmopathy (TAO), or Graves' ophthalmopathy or orbitopathy (GO), as well as antibodies, or antigen binding fragments thereof, and pharmaceutical compositions comprising them, useful in the methods.
    Type: Application
    Filed: March 10, 2022
    Publication date: November 10, 2022
    Inventors: Jeffrey W. SHERMAN, Dennis A. BENNETT, Srini RAMANATHAN, Yan XIN, Elizabeth THOMPSON, Elizabeth O'NEILL
  • METHODS FOR THE TREATMENT OF SCLERODERMA AND RELATED CONDITIONS
    Publication number: 20210253686
    Abstract: Provided herein are antibodies against insulin-like growth factor 1 receptor (IGF-1R) and their use in methods of treatment of, and achievement of clinical outcomes in, scleroderma and forms thereof, including diffuse cutaneous systemic sclerosis.
    Type: Application
    Filed: February 4, 2021
    Publication date: August 19, 2021
    Inventors: Elizabeth THOMPSON, Srini RAMANATHAN
  • METHODS FOR THE TREATMENT OF THYROID EYE DISEASE
    Publication number: 20210253719
    Abstract: Provided herein are methods of treating or reducing the severity of thyroid eye disease (TED), also known as thyroid-associated ophthalmopathy (TAO), or Graves' ophthalmopathy or orbitopathy (GO), as well as antibodies, or antigen binding fragments thereof, and pharmaceutical compositions comprising them, useful in the methods.
    Type: Application
    Filed: March 3, 2021
    Publication date: August 19, 2021
    Inventors: Jeffrey W. SHERMAN, Dennis A. BENNETT, Srini RAMANATHAN, Yan XIN, Elizabeth THOMPSON, Elizabeth O'NEILL