Patents by Inventor Srinivas Murali

Srinivas Murali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of pulmonary arterial endothelial cells from patients with pulmonary vascular disease and uses thereof
    Patent number: 10481151
    Abstract: The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: November 19, 2019
    Assignee: Allegheny-Singer Research Institute
    Inventors: Michael J. Passineau, Srinivas Murali, Raymond L. Benza, Jonathan B. Pollett
  • ISOLATION OF PULMONARY ARTERIAL ENDOTHELIAL CELLS FROM PATIENTS WITH PULMONARY VASCULAR DISEASE AND USES THEREOF
    Publication number: 20180067104
    Abstract: The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.
    Type: Application
    Filed: November 8, 2017
    Publication date: March 8, 2018
    Inventors: Michael J. Passineau, Srinivas Murali, Raymond L. Benza, Jonathan B. Pollett
  • Isolation of pulmonary arterial endothelial cells from patients with pulmonary vascular disease and uses thereof
    Patent number: 9835617
    Abstract: The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient, subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: December 5, 2017
    Assignee: Allegheny-Singer Research Institute
    Inventors: Michael J. Passineau, Srinivas Murali, Raymond L. Benza, Jonathan B. Pollett
  • ISOLATION OF PULMONARY ARTERIAL ENDOTHELIAL CELLS FROM PATIENTS WITH PULMONARY VASCULAR DISEASE AND USES THEREOF
    Publication number: 20150219631
    Abstract: The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient, subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.
    Type: Application
    Filed: September 10, 2013
    Publication date: August 6, 2015
    Inventors: Michael J. Passineau, Srinivas Murali, Raymond L. Benza, Jonathan B. Pollett