Patents by Inventor Srinivas R Viswanathan

Srinivas R Viswanathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to regulate miRNA processing by targeting Lin-28
    Patent number: 8283331
    Abstract: The present invention relates generally to methods to regulate microRNA (miRNA) biogenesis, in particular the regulation of the processing of pri-miRNA to mature miRNA by Lin-28 and/or variants such as Lin28B. In particular, the present invention relates to methods and compositions comprising at least one agent which inhibits Lin-28 function or activity and/or expression to increase the processing of pri-mRNA to mature miRNA. More specifically, one aspect of the invention is directed to treating and/or preventing cancer in a subject by administering an agent that inhibits Lin-28 activity or expression to a subject, preferably a human subject.
    Type: Grant
    Filed: October 8, 2008
    Date of Patent: October 9, 2012
    Assignee: Children's Medical Center Corporation
    Inventors: Richard I Gregory, George Q Daley, Srinivas R Viswanathan
  • METHODS TO REGULATE MIRNA PROCESSING BY TARGETING LIN-28
    Publication number: 20100221266
    Abstract: The present invention relates generally to methods to regulate microRNA (miRNA) biogenesis, in particular the regulation of the processing of pri-miRNA to mature miRNA by Lin-28 and/or variants such as Lin28B. In particular, the present invention relates to methods and compositions comprising at least one agent which inhibits Lin-28 function or activity and/or expression to increase the processing of pri-mRNA to mature miRNA. More specifically, one aspect of the invention is directed to treating and/or preventing cancer in a subject by administering an agent that inhibits Lin-28 activity or expression to a subject, preferably a human subject.
    Type: Application
    Filed: October 8, 2008
    Publication date: September 2, 2010
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Richard I. Gregory, George Q Daley, Srinivas R Viswanathan