Patents by Inventor Srinivas Rapireddy

Srinivas Rapireddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND DEVICES FOR DETECTING AND IDENTIFYING MICROORGANISMS
    Publication number: 20230183820
    Abstract: Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample are disclosed herein.
    Type: Application
    Filed: July 21, 2022
    Publication date: June 15, 2023
    Applicant: HELIXBIND, INC.
    Inventors: Alon Singer, Ranjit Prakash, Srinivas Rapireddy, Jork Nolling
  • Methods and devices for detecting and identifying microorganisms
    Patent number: 11414712
    Abstract: Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample are disclosed herein.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: August 16, 2022
    Assignee: HELIXBIND, INC.
    Inventors: Alon Singer, Ranjit Prakash, Srinivas Rapireddy, Jork Nolling
  • Template-directed PNA synthesis process and PNA targeting compounds
    Patent number: 11319349
    Abstract: Described herein are recognition modules that bind specifically to a template nucleic acid and which ligate together in a reducing environment to produce a gamma peptide nucleic acid (?PNA) oligomer. Also provided are methods of synthesizing a ?PNA oligomer on a template using the recognition modules.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: May 3, 2022
    Assignee: Carnegie Mellon University
    Inventors: Danith H. Ly, Raman Bahal, Dinesh Chandra Bhunia, Yidan Cong, Arunava Manna, Srinivas Rapireddy
  • Conformationally-preorganized, MiniPEG-containing gamma-peptide nucleic acids
    Patent number: 11279736
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: March 22, 2022
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20210214397
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Application
    Filed: August 26, 2020
    Publication date: July 15, 2021
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. LY, Srinivas RAPIREDDY, Bichismita SAHU
  • Conformationally-preorganized, miniPEG-containing ?-peptide nucleic acids
    Patent number: 10793605
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: October 6, 2020
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • Template-Directed PNA Synthesis Process and PNA Targeting Compounds
    Publication number: 20190337986
    Abstract: Described herein are recognition modules that bind specifically to a template nucleic acid and which ligate together in a reducing environment to produce a gamma peptide nucleic acid (?PNA) oligomer. Also provided are methods of synthesizing a ?PNA oligomer on a template using the recognition modules.
    Type: Application
    Filed: January 17, 2019
    Publication date: November 7, 2019
    Inventors: Danith H. Ly, Raman Bahal, Dinesh Chandra Bhunia, Yidan Cong, Arunava Manna, Srinivas Rapireddy
  • CONFORMATIONALLY-PREORGANIZED, MINIPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20190292227
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • Conformationally-preorganized, miniPEG-containing gamma-peptide nucleic acids
    Patent number: 10364272
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: July 30, 2019
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20190062378
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Application
    Filed: September 27, 2018
    Publication date: February 28, 2019
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • Conformationally-preorganized, miniPEG-containing gamma-peptide nucleic acids
    Patent number: 10160787
    Abstract: Described are ?-PNA monomers, methodology for synthesizing them, and methodology for synthesizing PNA oligomers that incorporate them.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: December 25, 2018
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20180291065
    Abstract: Described are ?-PNA monomers, methodology for synthesizing them, and methodology for synthesizing PNA oligomers that incorporate them.
    Type: Application
    Filed: May 7, 2018
    Publication date: October 11, 2018
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. LY, Srinivas RAPIREDDY, Bichismita SAHU
  • Conformationally-preorganized, MiniPEG-containing gamma-peptide nucleic acids
    Patent number: 10093700
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: October 9, 2018
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • METHODS AND DEVICES FOR DETECTING AND IDENTIFYING MICROORGANISMS
    Publication number: 20170292146
    Abstract: Methods and devices for isolating microbial cells from a sample, extracting eukaryotic DNA from a sample, and identifying the microbial species in the sample are disclosed herein.
    Type: Application
    Filed: September 17, 2015
    Publication date: October 12, 2017
    Inventors: Alon Singer, Ranjit Prakash, Srinivas Rapireddy, Jork Nolling
  • CONFORMATIONALLY-PREORGANIZED, MiniPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20160096867
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 7, 2016
    Applicant: CARNEGIE MELLON UNIVERSITY CENTER FOR TECHNOLOGY TRANSFER & ENTERPRISE
    Inventors: Danith H. LY, Srinivas RAPIREDDY, Bichismita SAHU
  • TEMPLATE-DIRECTED GAMMAPNA SYNTHESIS PROCESS AND GAMMAPNA TARGETING COMPOUNDS
    Publication number: 20160083433
    Abstract: Described herein are recognition modules that bind specifically to a template nucleic acid and which ligate together in a reducing environment to produce a gamma peptide nucleic acid (?PNA) oligomer. Also provided are methods of synthesizing a ?PNA oligomer on a template using the recognition modules.
    Type: Application
    Filed: April 11, 2014
    Publication date: March 24, 2016
    Applicant: Carnegie Mellon University
    Inventors: Danith H. Ly, Raman Bahal, Arunava Manna, Dinesh Chandra Bhunia, Srinivas Rapireddy, Yidan Cong
  • Conformationally-preorganized, miniPEG-containing ?-peptide nucleic acids
    Patent number: 9193758
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: November 24, 2015
    Assignee: Carnegie Mellon University Center for Technology Transfer & Enterprise
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu
  • CONFORMATIONALLY-PREORGANIZED, MINIPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS
    Publication number: 20140128570
    Abstract: The present invention relates to ?-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
    Type: Application
    Filed: April 6, 2012
    Publication date: May 8, 2014
    Inventors: Danith H. Ly, Srinivas Rapireddy, Bichismita Sahu