Patents by Inventor Srinivas Simhadri

Srinivas Simhadri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of montelukast sodium
    Patent number: 9487487
    Abstract: Disclosed is a process for the preparation of montelukast sodium. The process comprises a) reacting 2-(2-(3(S)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-hydroxypropyl)phenyl)-2-propanol with methane sulfonyl chloride and coupling the resultant mesylate compound with 1-(mercaptomethyl)cyclopropane acetic acid in presence of a base and free alkali source followed by saltification with an amine in a single step reaction and b) converting the montelukast amine salt to montelukast sodium salt.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: November 8, 2016
    Assignee: LAURUS LABS PRIVATE LIMITED
    Inventors: Srinivas Simhadri, Yaseen Mohammad, Venkata S. Indukuri, Seeta R. Gorantla, Satyanarayana Chava
  • Process for the preparation of atazanavir bisulfate
    Patent number: 9382207
    Abstract: The present invention relates to an improved process for the preparation of Atazanavir bisulfate Form A. The present invention also relates to a pharmaceutical composition using the Atazanavir bisulfate Form A of the invention.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: July 5, 2016
    Assignee: Laurus Labs Private Limited
    Inventors: Srinivas Simhadri, Yaseen Mohammad, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla
  • PROCESS FOR THE PREPARATION OF ATAZANAVIR BISULFATE
    Publication number: 20150183742
    Abstract: The present invention relates to an improved process for the preparation of Atazanavir bisulfate Form A. The present invention also relates to a pharmaceutical composition using the Atazanavir bisulfate Form A of the invention.
    Type: Application
    Filed: August 22, 2013
    Publication date: July 2, 2015
    Inventors: Srinivas Simhadri, Yaseen Mohammad, Venkata Sunil Kumar Indukuri, Seeta Ramanjaneyulu Gorantla
  • Process for preparing Montelukast and salts thereof
    Patent number: 8367834
    Abstract: A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercaptomethyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: February 5, 2013
    Assignee: Laurus Labs Private Limited
    Inventors: Venkata Sunil Kumar Indukuri, Srinivas Simhadri, Satyanarayana Chava
  • PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
    Publication number: 20120232276
    Abstract: A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyliphenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 13, 2012
    Inventors: Venkata Sunil Kumar INDUKURI, Srinivas SIMHADRI, Satyanarayana CHAVA
  • Process for preparing montelukast and salts thereof
    Patent number: 8207343
    Abstract: A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-isopropenylphenyl)propyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.
    Type: Grant
    Filed: May 25, 2009
    Date of Patent: June 26, 2012
    Assignee: Laurus Labs Private Limited
    Inventors: Venkata Sunil Kumar Indukuri, Srinivas Simhadri, Satyanarayana Chava
  • IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF
    Publication number: 20110112300
    Abstract: A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercapto methyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.
    Type: Application
    Filed: May 25, 2009
    Publication date: May 12, 2011
    Applicant: Aptuit Laurus Pvt. Ltd.
    Inventors: Venkata Sunil Kumar Indukuri, Srinivas Simhadri, Satyanarayana Chava
  • PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS THEREOF
    Publication number: 20110092708
    Abstract: The present invention relates to the alkyl amine salts of Montelukast and methods for their preparation and conversion of Montelukast amine salts to Montelukast or Montelukast alkali/alkaline salt.
    Type: Application
    Filed: July 31, 2007
    Publication date: April 21, 2011
    Inventors: Seeta Ramanjaneyulu Gorantla, Mohan Bandari, Venkata Sunil Kumar Indukuri, Srinivas Simhadri, Narasimha Rao Ketavarapu, Venkata Krishna Kishore Jammulaveera, Yaseen Mohammed
  • Process for the Preparation of Montelukast and its Salts
    Publication number: 20090143590
    Abstract: The present invention relates to an improved process for the preparation of 1-[[[(1R)-1-[3[(1E)-2-(7chloro-2-quinolinyl) ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic acid (Formula-1) and its salts using Methyl 2-[(3S)-[3-[(2E)-(7-chloro quinolin-2-yl) ethenyl] phenyl]-3-halopropyl] benzoate (Formula-2)
    Type: Application
    Filed: July 19, 2004
    Publication date: June 4, 2009
    Applicant: MATRIX LABORATORIES LTD.
    Inventors: Satyanarayana Chava, Seeta Ramanjaneyulu Gorantla, Venkata Sunil Kumar Indukuri, Srinivas Simhadri, Vera Venkata Krishna Kishore Jammula