Patents by Inventor Srinivasa Raju Sammeta

Srinivasa Raju Sammeta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRAZOLYL COMPOUNDS AS MALT-1 INHIBITORS
    Publication number: 20240132475
    Abstract: The present invention is directed to compound of formula (I) and, a pharmaceutically acceptable salt or a stereoisomer thereof that useful as MALT-1 inhibitors for the treatment of diseases or disorders dependent on MALT-1. The present invention also relates to a method of preparation of the said compounds and pharmaceutical compositions comprising the said compounds.
    Type: Application
    Filed: February 3, 2022
    Publication date: April 25, 2024
    Applicant: AURIGENE ONCOLOGY LIMITED
    Inventors: Dinesh CHIKKANNA, Susanta SAMAJDAR, Srinivasa Raju SAMMETA, Sunil Kumar PANIGRAHI
  • Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors
    Patent number: 11542275
    Abstract: The present invention relates to substituted imidazolidin-2-one derivatives of formula (I) or pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and utility as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions and disorders mediated by PRMT5, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: January 3, 2023
    Assignee: AURIGENE DISCOVERY TECHNOLOGIES LIMITED
    Inventors: Dinesh Chikkanna, Sunil Kumar Panigrahi, Srinivasa Raju Sammeta
  • IMIDAZOLIDIN-2-ONE COMPOUNDS AS PRMT5 MODULATORS
    Publication number: 20220324878
    Abstract: The present invention relates to the derivatives of compound of formula (I) and pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and use thereof as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions where PRMT5 inhibition is desired, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 13, 2022
    Inventors: Dinesh CHIKKANNA, Sunil Kumar PANIGRAHI, Srinivasa Raju SAMMETA, Wohlfahrt GERD, Myllymaki MIKKO
  • Imidazolidin-2-one compounds as PRMT5 modulators
    Patent number: 11365205
    Abstract: The present invention relates to the derivatives of compound of formula (I) and pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and use thereof as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions where PRMT5 inhibition is desired, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: June 21, 2022
    Assignee: AURIGENE DISCOVERY TECHNOLOGIES LIMITED
    Inventors: Dinesh Chikkanna, Sunil Kumar Panigrahi, Srinivasa Raju Sammeta, Wohlfahrt Gerd, Myllymaki Mikko
  • IMIDAZOLIDIN-2-ONE COMPOUNDS AS PRMT5 MODULATORS
    Publication number: 20210002299
    Abstract: The present invention relates to the derivatives of compound of formula (I) and pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and use thereof as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions where PRMT5 inhibition is desired, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.
    Type: Application
    Filed: March 20, 2019
    Publication date: January 7, 2021
    Inventors: Dinesh CHIKKANNA, Sunil Kumar PANIGRAHI, Srinivasa Raju SAMMETA, Wohlfahrt GERD, Myllymaki MIKKO
  • SUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES AS PRMT5 INHIBITORS
    Publication number: 20210002298
    Abstract: The present invention relates to substituted imidazolidin-2-one derivatives of formula (I) or pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and utility as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions and disorders mediated by PRMT5, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.
    Type: Application
    Filed: March 20, 2019
    Publication date: January 7, 2021
    Inventors: Dinesh CHIKKANNA, Sunil Kumar PANIGRAHI, Srinivasa Raju SAMMETA
  • NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE
    Publication number: 20120004213
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Application
    Filed: September 15, 2011
    Publication date: January 5, 2012
    Applicant: FOREST LABORATORIES HOLDINGS LIMITED
    Inventors: Kumar SUNDARESAN, Sandeep N. RAIKAR, Srinivasa Raju SAMMETA, Ganesh PRABHU, Hosahalli SUBRAMANYA, Alexander BISCHOFF
  • Piperazine derivatives as inhibitors of stearoyl-CoA desaturase
    Patent number: 8039463
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: October 18, 2011
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Kumar Sundaresan, Sandeep N. Raikar, Srinivasa Raju Sammeta, Ganesh Prabhu, Hosahalli Subramanya, Alexander Bischoff
  • NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE
    Publication number: 20110046134
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Application
    Filed: October 29, 2010
    Publication date: February 24, 2011
    Inventors: Alexander Bischoff, Hosahalli Subramanya, Kumar Sundaresan, Srinivasa Raju Sammeta, Anil Kumar Vaka
  • Piperazine derivatives as inhibitors of stearoyl-CoA desaturase
    Patent number: 7842696
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: November 30, 2010
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Alexander Bischoff, Hosahalli Subramanya, Kumar Sundaresan, Srinivasa Raju Sammeta, Anil Kumar Vaka
  • NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE
    Publication number: 20100160323
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 24, 2010
    Inventors: Alexander Bischoff, Hosahalli Subramanya, Kumar Sundaresan, Srinivasa Raju Sammeta, Anil Kumar Vaka
  • NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE
    Publication number: 20090239848
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Application
    Filed: March 20, 2009
    Publication date: September 24, 2009
    Applicant: FOREST LABORATORIES HOLDINGS LIMITED
    Inventors: Kumar Sundaresan, Sandeep N. Raikar, Srinivasa Raju Sammeta, Ganesh Prabhu, Hosahalli S. Subramanya, Alexander Bischoff
  • NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE
    Publication number: 20090221583
    Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
    Type: Application
    Filed: June 23, 2008
    Publication date: September 3, 2009
    Applicants: FOREST LABORATORIES HOLDINGS LIMITED, AURIGENE DISCOVERY TECHNOLOGIES LIMITED
    Inventors: Alexander BISCHOFF, Hosahalli SUBRAMANYA, Kumar SUNDARESAN, Srinivasa Raju SAMMETA, Anil Kumar VAKA