Patents by Inventor Srinivasa Reddy Natala

Srinivasa Reddy Natala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING
    Publication number: 20240043395
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Application
    Filed: September 24, 2021
    Publication date: February 8, 2024
    Inventors: Srinivasa Reddy NATALA, Wolfgang J. WRASIDLO, Emily M. STOCKING
  • SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF
    Publication number: 20230391734
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: June 5, 2023
    Publication date: December 7, 2023
    Applicant: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. WRASIDLO, Emily M. STOCKING, Srinivasa Reddy NATALA, Diana Luz PRICE
  • Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
    Patent number: 11708338
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: July 25, 2023
    Assignee: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. Wrasidlo, Emily M. Stocking, Srinivasa Reddy Natala, Diana Luz Price
  • COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS
    Publication number: 20230112980
    Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
    Type: Application
    Filed: October 19, 2022
    Publication date: April 13, 2023
    Inventors: Ha-Soon Choi, James Paul Lajiness, Srinivasa Reddy Natala, Bao Nguyen, Hank Michael James Petrassi, Zhicheng Wang
  • COMPOUNDS AS MODULATORS OF TLR2 SIGNALING
    Publication number: 20220396583
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Application
    Filed: April 25, 2022
    Publication date: December 15, 2022
    Applicant: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy NATALA, Wolfgang Wrasidlo
  • Compounds and compositions for inducing chondrogenesis
    Patent number: 11510912
    Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: November 29, 2022
    Assignee: Novartis AG
    Inventors: Ha-Soon Choi, James Paul Lajiness, Srinivasa Reddy Natala, Bao Nguyen, Hank Michael James Petrassi, Zhicheng Wang
  • COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING
    Publication number: 20220298155
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Application
    Filed: February 10, 2022
    Publication date: September 22, 2022
    Applicant: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy NATALA, Wolfgang J. WRASIDLO, Emily M. STOCKING
  • Compounds as modulators of TLR2 signaling
    Patent number: 11345713
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: May 31, 2022
    Assignee: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy Natala, Wolfgang Wrasidlo
  • Compounds and compositions as modulators of TLR signaling
    Patent number: 11299487
    Abstract: The present disclosure relates to substituted aryl and heteroaryl compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: April 12, 2022
    Assignee: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy Natala, Wolfgang J. Wrasidlo, Emily M. Stocking
  • SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF
    Publication number: 20210300881
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: April 6, 2021
    Publication date: September 30, 2021
    Applicant: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. WRASIDLO, Emily M. STOCKING, Srinivasa Reddy NATALA, Diana Luz PRICE
  • METHOD OF TREATING A CONDITION ASSOCIATED WITH NEURODEGENERATION USING INHIBITORS OF OAT3
    Publication number: 20210290597
    Abstract: The present disclosure relates to therapeutic agents that may be useful intreatment and prophylaxis of neurodegenerative disorders and/or neural inflammation.
    Type: Application
    Filed: June 20, 2019
    Publication date: September 23, 2021
    Applicant: Neuropore Therapies, Inc.
    Inventors: Douglas W. BONHAUS, Wolfgang J. WRASIDLO, Emily M. STOCKING, Srinivasa Reddy NATALA
  • Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
    Patent number: 11008294
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: May 18, 2021
    Assignee: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. Wrasidlo, Emily M. Stocking, Srinivasa Reddy Natala, Diana Luz Price
  • COMPOUNDS AS MODULATORS OF TLR2 SIGNALING
    Publication number: 20210024539
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Application
    Filed: March 27, 2019
    Publication date: January 28, 2021
    Applicant: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy NATALA, Wolfgang WRASIDLO
  • COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING
    Publication number: 20200308163
    Abstract: The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.
    Type: Application
    Filed: March 25, 2020
    Publication date: October 1, 2020
    Applicant: Neuropore Therapies, Inc.
    Inventors: Srinivasa Reddy NATALA, Wolfgang J. WRASIDLO, Emily M. STOCKING
  • COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS
    Publication number: 20200237737
    Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
    Type: Application
    Filed: April 14, 2020
    Publication date: July 30, 2020
    Inventors: Ha-Soon Choi, James Paul Lajiness, Srinivasa Reddy Natala, Bao Nguyen, Hank Michael James Petrassi, Zhicheng Wang
  • Compounds and compositions for inducing chondrogenesis
    Patent number: 10660881
    Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: May 26, 2020
    Assignee: Novartis AG
    Inventors: Ha-Soon Choi, James Paul Lajiness, Srinivasa Reddy Natala, Bao Nguyen, Hank Michael James Petrassi, Zhicheng Wang
  • SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF
    Publication number: 20200123116
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: October 24, 2019
    Publication date: April 23, 2020
    Applicant: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. WRASIDLO, Emily M. STOCKING, Srinivasa Reddy NATALA, Diana Luz PRICE
  • Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof
    Patent number: 10501423
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: December 10, 2019
    Assignee: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. Wrasidlo, Emily M. Stocking, Srinivasa Reddy Natala, Diana Luz Price
  • COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS
    Publication number: 20190314348
    Abstract: The present invention provides compounds of formula I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds, and methods of using such compounds for treatment of joint damage or joint injury in a mammal, and for inducing differentiation of mesenchymal stem cells into chondrocytes.
    Type: Application
    Filed: June 21, 2019
    Publication date: October 17, 2019
    Inventors: Ha-Soon Choi, James Paul Lajiness, Srinivasa Reddy Natala, Bao Nguyen, Hank Michael James Petrassi, Zhicheng Wang
  • SUBSTITUTED PHENYL SULFONYL PHENYL TRIAZOLE THIONES AND USES THEREOF
    Publication number: 20190292158
    Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.
    Type: Application
    Filed: March 27, 2019
    Publication date: September 26, 2019
    Applicant: Neuropore Therapies, Inc.
    Inventors: Wolfgang J. WRASIDLO, Emily M. STOCKING, Srinivasa Reddy NATALA, Diana Luz PRICE