Patents by Inventor Srinivasu Pothukanuri

Srinivasu Pothukanuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isoquinolines as potassium ion channel inhibitors
    Patent number: 9458133
    Abstract: A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 4, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Naveen Kumar Dhondi, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Pyrrolopyridazines as potassium ion channel inhibitors
    Patent number: 9458164
    Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 4, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • Pyrrolotriazines as potassium ion channel inhibitors
    Patent number: 9403834
    Abstract: A compound of formula (I), wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: August 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160016961
    Abstract: A compound of formula (I) wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • ISOQUINOLINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160016933
    Abstract: A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Naveen Kumar Dhondi, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • PYRROLOTRIAZINES AS POTASSIUM ION CHANNEL INHIBITORS
    Publication number: 20160009719
    Abstract: A compound of formula (I), wherein A, R1, R3, and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 14, 2016
    Inventors: Heather Finlay, Ashok Kumar Adisechan, Prashantha Gunaga, John Lloyd, Srinivasu Pothukanuri
  • CYCLITOLS AND THEIR DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20140171394
    Abstract: The present invention is directed to polyphosphorylated and pyrophosphate derivatives of cyclitols. More particularly, the invention relates to polyphosphorylated and pyrophosphate derivatives of inositols. The invention also relates to compositions of the polyphosphorylated and pyrophosphate derivatives of inositol and other similar, more lipophilic derivatives, and their use as allosteric effectors, cell-signaling molecule analogs, and therapeutic agents.
    Type: Application
    Filed: December 9, 2013
    Publication date: June 19, 2014
    Applicants: Universite de Strasbourg, NormOxys, Inc.
    Inventors: Jean-Marie Lehn, Srinivasu Pothukanuri, Alexandros Koumbis, Carolina Duarte, Claude Nicolau
  • PHOSPHORYLATED POLYOLS, PYROPHOSPHATES, AND DERIVATIVES THEREOF HAVING BIOLOGICAL ACTIVITY
    Publication number: 20140142052
    Abstract: The present invention provides phosphorylated and pyrophosphate derivatives of polyols, and structural derivatives of these compounds, and provides pharmaceutical compositions comprising the same. The compounds and compositions disclosed herein have various biological activities, including for example, as allosteric effectors of hemoglobin and/or as kinase inhibitors. The present invention further provides methods for therapy in human or mammalian patients, and methods for synthesis of biologically active compounds and their intermediates.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 22, 2014
    Applicant: NormOxys, Inc.
    Inventors: Jean-Marie Lehn, Yves Claude Nicolau, Srinivasu Pothukanuri, Adam Brockman, John Hey, Jeremy Yu
  • CYCLITOLS AND THEIR DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20130190524
    Abstract: The present invention is directed to polyphosphorylated and pyrophosphate derivatives of cyclitols. More particularly, the invention relates to polyphosphorylated and pyrophosphate derivatives of inositols. The invention also relates to compositions of the polyphosphorylated and pyrophosphate derivatives of inositol and other similar, more lipophilic derivatives, and their use as allosteric effectors, cell-signaling molecule analogs, and therapeutic agents.
    Type: Application
    Filed: August 22, 2012
    Publication date: July 25, 2013
    Applicants: UNIVERSITE DE STRASBOURG, NORMOXYS, INC.
    Inventors: Jean-Marie Lehn, Srinivasu Pothukanuri, Alexandros Koumbis, Carolina Duarte, Claude Nicolau
  • Cyclitols and Their Derivatives and Their Therapeutic Applications
    Publication number: 20080200437
    Abstract: The present invention is directed to polyphosphorylated and pyrophosphate derivatives of cyclitols. More particularly, the invention relates to polyphosphorylated and pyrophosphate derivatives of inositols. The invention also relates to compositions of the polyphosphorylated and pyrophosphate derivatives of inositol and other similar, more lipophilic derivatives, and their use as allosteric effectors, cell-signaling molecule analogs, and therapeutic agents.
    Type: Application
    Filed: December 31, 2007
    Publication date: August 21, 2008
    Inventors: Jean-Marie Lehn, Srinivasu Pothukanuri, Alexandros Koumbis, Carolina Duarte, Claude Nicolau