Patents by Inventor Sripathy Venkatraman

Sripathy Venkatraman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LFA-1 inhibitor and methods of preparation and polymorph thereof
    Patent number: 10906892
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: February 2, 2021
    Assignee: NOVARTIS PHARMACEUTICALS CORPORATION
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C. A. Brot, Subashree Iyer, Michael Hall
  • Continuous flow carboxylation reaction
    Patent number: 10899715
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: January 26, 2021
    Assignee: NOVARTIS AG
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF
    Publication number: 20190382389
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Application
    Filed: January 15, 2019
    Publication date: December 19, 2019
    Applicant: SARcode Bioscience Inc.
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C.A. Brot, Subashree Iyer, Michael Hall
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20190300485
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 3, 2019
    Applicant: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • Continuous flow carboxylation reaction
    Patent number: 10273212
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 30, 2019
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • LFA-1 inhibitor and methods of preparation and polymorph thereof
    Patent number: 10214517
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: February 26, 2019
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C. A. Brot, Subashree Iyer, Michael Hall
  • LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF
    Publication number: 20180118726
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Application
    Filed: June 13, 2017
    Publication date: May 3, 2018
    Applicant: SARcode Bioscience Inc.
    Inventors: James Robert ZELLER, Sripathy VENKATRAMAN, Elisabeth C. A. BROT, Subashree IYER, Michael HALL
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20180118689
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: June 28, 2017
    Publication date: May 3, 2018
    Applicant: SARCODE BIOSCIENCE INC.
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • Continuous flow carboxylation reaction
    Patent number: 9725413
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 8, 2017
    Inventors: Scott Tweedie, Sripathy Venkatraman, James Zeller
  • LFA-1 inhibitor and methods of preparation and polymorph thereof
    Patent number: 9708303
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: July 18, 2017
    Assignee: SARCODE BIOSCIENCE INC.
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C. A. Brot, Subashree Iyer, Michael Hall
  • Synthesis of a neurostimulative piperazine
    Patent number: 9481649
    Abstract: The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: November 1, 2016
    Assignee: NEURALSTEM, INC.
    Inventors: Sripathy Venkatraman, Syed Mahmood, Bingidimi I. Mobele, Olga Lapina, Kellie Vercoe, Ying Li, Jonathan Salsbury, Mark McLaws
  • SYNTHESIS OF A NEUROSTIMULATIVE PIPERAZINE
    Publication number: 20160090358
    Abstract: The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Applicant: NEURALSTEM, INC.
    Inventors: Sripathy VENKATRAMAN, Syed MAHMOOD, Bingidimi I. MOBELE, Olga LAPINA, Kellie VERCOE, Ying LI, Jonathan SALSBURY, Mark MCLAWS
  • CONTINUOUS FLOW CARBOXYLATION REACTION
    Publication number: 20160090361
    Abstract: The present invention is related to a two-step carboxylation reaction of an aryl group using continuous flow reaction conditions. This process permits large scale synthesis of useful reaction products in high yield.
    Type: Application
    Filed: September 25, 2015
    Publication date: March 31, 2016
    Inventors: Scott Tweedie, Sripathy Venkatraman, Shuhong Liu, James Zeller, Elisabeth Brot, Michael Hamlin, Mary Newman, Mark McLaws, John Rosenberg, David Lathbury
  • Synthesis of a neurostimulative piperazine
    Patent number: 9278933
    Abstract: The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: March 8, 2016
    Assignee: NEURALSTEM, INC.
    Inventors: Sripathy Venkatraman, Syed Mahmood, Bingidimi I. Mobele, Olga Lapina, Kellie Vercoe, Ying Li, Jonathan Salsbury, Mark McLaws
  • LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF
    Publication number: 20150336939
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Application
    Filed: June 23, 2015
    Publication date: November 26, 2015
    Applicant: SARCODE BIOSCIENCE INC.
    Inventors: James Robert ZELLER, Sripathy VENKATRAMAN, Elisabeth C. A. BROT, Subashree IYER, Michael HALL
  • LFA-1 inhibitor and methods of preparation and polymorph thereof
    Patent number: 9085553
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: July 21, 2015
    Assignee: SARCODE BIOSCIENCE, INC.
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C. A. Brot, Subashree Iyer, Michael Hall
  • LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF
    Publication number: 20140031387
    Abstract: Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed.
    Type: Application
    Filed: July 25, 2013
    Publication date: January 30, 2014
    Applicant: SARcode Bioscience Inc.
    Inventors: James Robert Zeller, Sripathy Venkatraman, Elisabeth C. A. Brot, Subashree Iyer, Michael Hall
  • SYNTHESIS OF A NEUROSTIMULATIVE PIPERAZINE
    Publication number: 20130005974
    Abstract: The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.
    Type: Application
    Filed: August 24, 2010
    Publication date: January 3, 2013
    Applicant: NEURALSTEM, INC.
    Inventors: Sripathy Venkatraman, Syed Mahmood, Bingidimi I. Mobele, Olga Lapina, Kellie Vercoe, Ying Li, Jonathan Salsbury, Mark McLaws
  • Dipeptidyl peptidase inhibitors
    Patent number: 8222411
    Abstract: Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: July 17, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Paul R. Brodfuahrer, Bruce Elder, Paul Isbester, Richard S. Fornicola, Philip B. Kisanga, Bingidimi I. Mobele, Grant J. Palmer, Maxwell M. Reeve, Jonathon S. Salsbury, Luckner Ulysse, Sripathy Venkatraman
  • DIPEPTIDYL PEPTIDASE INHIBITORS
    Publication number: 20090275750
    Abstract: Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.
    Type: Application
    Filed: September 15, 2006
    Publication date: November 5, 2009
    Inventors: Jun Feng, Stephen L. Gwaltney, Jeffrey A. Stafford, Zhiyuan Zhang, Paul R. Brodluahrer, Bruce Elder, Paul Isbester, Richard S. Fornicola, Philip B. Kisanga, Bingidimi I. Mobele, Grant J. Palmer, Maxwell M. Reeve, Jonathon S. Salsbury, Luckner Ulysse, Sripathy Venkatraman