Patents by Inventor Sripriya Ravindra Kumar

Sripriya Ravindra Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AAV VARIANTS WITH ENHANCED TROPISM
    Publication number: 20220281922
    Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.
    Type: Application
    Filed: July 31, 2020
    Publication date: September 8, 2022
    Inventors: Dinah Wen-Yee SAH, Jinzhao HOU, Kei ADACHI, Wei WANG, Qingmin CHEN, Jenna CARROLL SOPER, Amy REN, Xiao-Qin REN, Benjamin E. DEVERMAN, Viviana GRADINARU, Qin HUANG, Sripriya RAVINDRA KUMAR
  • VIRUS COMPOSITIONS WITH ENHANCED SPECIFICITY IN THE BRAIN
    Publication number: 20220220502
    Abstract: Provided are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with tropisms showing increased specificity and efficiency of viral transduction in targeted cell-types, for e.g., the brain and the liver. Therapeutic and bio-medical research applications of the rAAVs are also described, including without limitation methods of discovering rAAVs using a multiplexed Cre recombination-based AAV targeted evolution (M-CREATE) method, and methods of treating various diseases and conditions by rAAV-mediated transgene therapy.
    Type: Application
    Filed: April 10, 2020
    Publication date: July 14, 2022
    Inventors: Viviana Gradinaru, Sripriya Ravindra Kumar, Benjamin Deverman